Feb 15 2019 MedUni Vienna study in the top journal “The Lancet” The conformance of genetic characteristics is essential for the long-term function after kidney transplantation. This is the central result of a recent study in the top journal “The Lancet” with more than 500 patients after kidney transplantation, conducted by a global consortium led […]Continue Reading ...
Feb 13 2019 Method for growing kidney organoids under flow enhances their vascularization and maturation, increasing their potential for drug testing and regenerative medicine In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the […]Continue Reading ...
Scientists have identified an enzyme that is a “master regulator” of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals. As reported in Nature Communications, a global research team led by the University of Bristol studied how the […]Continue Reading ...
TUESDAY, Jan. 22, 2019 — Whole-exome sequencing (WES) can identify a genetic cause for almost one-third of pediatric kidney transplant recipients, according to a study published online Jan. 17 in the Journal of the American Society of Nephrology. Nina Mann, M.D., from Boston Children’s Hospital, and colleagues examined the diagnostic yield of WES in pediatric […]Continue Reading ...
Sechenov University together with their German colleagues suggest a new highly sensitive, quick, and pain-free method for diagnosing kidney cancer. This method is based on measuring of the immune response to arrestin-1, a retina protein that is synthesized in the cancerous cells of kidneys. Tumors can be benign or malignant. The first ones are not […]Continue Reading ...
This image shows a cross section of a kidney. Credit: Holly Fischer/Wikipedia People with a certain type of advanced kidney cancer will not be able to have a combination of two immunotherapy drugs on the NHS in England. The National Institute for Health and Care Excellence (NICE) concluded that giving the immunotherapy drugs, called ipilimumab […]Continue Reading ...
DNA testing can identify a genetic culprit in about 10 percent of adults with chronic kidney disease and impacts treatment for most of them. A new study has found that genes cause about 1 in 10 cases of chronic kidney disease in adults, and identifying the responsible gene has a direct impact on treatment for […]Continue Reading ...
Dec 21 2018 CareDx, Inc., a leading molecular diagnostics company focused on the discovery, development and commercialization of clinically differentiated, high-value diagnostic solutions for transplant patients, today announces the publication of data demonstrating the clinical utility of measuring AlloSure in repeat kidney transplant recipients in the American Journal of Transplantation. AlloSure is the first donor-derived […]Continue Reading ...
Genetic changes can increase the risk of developing kidney stones, often acting in combination with a variety of environmental and lifestyle factors. Most genes involved in the condition are important for transmitting chemical signals from outside cells to inside cells or transporting materials in and out of cells. These processes help regulate the levels of […]Continue Reading ...
During development in the womb, immune cells called macrophages go to the kidneys, and they remain there for life. Understanding the possible healing role for these macrophages after kidney damage may be crucial to helping treat patients who suffer acute kidney injury. Acute kidney injury, or AKI, is a devastating condition that develops in two-thirds […]Continue Reading ...
The standard work-up of kidney transplant candidates is complex and includes many medical tests in part because most CKD patients are older and suffer from many comorbidities, for example, diabetes, hypertension or heart disease. According to the Annual Report of the ERA-EDTA Registry, the mean age of patients on renal replacement therapy is 61.5 years. […]Continue Reading ...
WEDNESDAY, Jan. 2, 2019 — Kidney stones are associated with an increased risk for renal cell carcinoma (RCC), specifically papillary RCC, and upper tract urothelial carcinoma (UTUC), according to a study published online Dec. 19 in the British Journal of Cancer. Jeroen A.A. van de Pol, from Maastricht University in the Netherlands, and colleagues examined […]Continue Reading ...
“There are multiple genetic causes of chronic kidney disease,” Ali Gharavi, chief of nephrology at the Vagelos College of Physicians and Surgeons, said in a news release.Continue Reading ...
DNA sequencing can be used to identify the underlying genetic cause of many rare types of chronic kidney disease, leading to better treatment, finds a new study from Columbia University.Continue Reading ...
COPENHAGEN, Denmark, Dec. 19, 2018 /PRNewswire/ — Veloxis Pharmaceuticals announced today that the U.S. Food & Drug Administration (FDA) approved a new indication for Envarsus XR (tacrolimus extended-release tablets) to prevent organ rejection in de novo kidney transplant patients in combination with other immunosuppressants. This indication is commonly referred to as the de novo indication. […]Continue Reading ...
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