Comparison of the abundance of several species between the I/R-injured and the sham-operated mice at pre-I/R and days 2 and 10. Credit: Kanazawa University Gut microbiota-derived metabolites play important roles in health and disease. In this study, we show the pathophysiological role of D-serine in association with the gut microbiota in humans and mice with […]Continue Reading ...
For the first time, scientists have described the body’s natural mechanism for temporarily protecting the powerhouses of kidney cells when injury or disease means they aren’t getting enough blood or oxygen. Powerhouses, called mitochondria, which provide fuel for our cells, start to fragment, likely as one of the first steps in the kidney cell damage […]Continue Reading ...
Aerobic exercise may reduce the risk of diabetes-related kidney disease in some people, according to a new study. The findings are published ahead of print in the American Journal of Physiology–Renal Physiology and was chosen as an APS select article for December. Kidney (renal) disease is a common complication associated with type 2 diabetes, especially […]Continue Reading ...
Myriad biological and societal factors can impact the occurrence and accelerate progression of chronic kidney disease (CKD) for children of African descent – including preterm birth, exposure to toxins during gestation and lower socioeconomic status – and can complicate these children’s access to effective treatments, according to an invited commentary published in the November 2018 […]Continue Reading ...
For the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future. Experts at Newcastle University, UK, have shown in a cell model and in a mouse model that gene editing could be used for Joubert syndrome to stop […]Continue Reading ...
A new study in Clinical Kidney Journal indicates that the usage of marijuana by kidney donors has no measurable effect upon the outcomes of kidney transplants for donors or recipients. This study is the first to investigate the effect of marijuana use by live kidney donors. The use of marijuana in the United States has […]Continue Reading ...
Researchers at New York Institute of Technology (NYIT) have secured a grant for $391,041 from the National Institutes of Health (NIH) that may allow for improved understanding of vascular calcification and prevent heart disease in chronic kidney disease patients. Cardiovascular disease is the most common cause of death in patients with chronic kidney disease. With […]Continue Reading ...
Scientists in Japan have found a ‘skeleton key’ for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease. The protein nephrin is a constituent of the kidney filtration […]Continue Reading ...
Researchers at the University of Illinois at Chicago have found that men with chronic kidney disease, or CKD, are more likely to experience disease progression and death when compared with women suffering from the same condition. CKD affects more than 26 million people in the United States. People with the condition experience gradual loss of […]Continue Reading ...
Advances in treating cancer, heart disease and other major health conditions in recent decades have extended life spans for millions of people. However, chronic kidney disease is an outlier, with cases accelerating at a faster pace than all other noninfectious diseases, according to a study from Washington University School of Medicine in St. Louis and […]Continue Reading ...
Congenital anomalies of kidney and urinary tract (CAKUT) is a group of abnormalities affecting the kidneys or other structures of the . The additional parts of the urinary tract that may be affected include the bladder, the tubes that carry urine from each kidney to the bladder (the ureters), and the tube that carries urine […]Continue Reading ...
Researchers at the Washington University School of Medicine in St. Louis have discovered the presence of rogue cells inside kidney organoids. The rogue cells, which were identified as brain and muscle cells, constituted 10-20% of the cells making up the organoid. Humphreys lab | Shutterstock Organoids are 3D cell cultures that self-organize to replicate an […]Continue Reading ...
Scientists led by Duke-NUS Medical School have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy. Genetic analyses of the mice led to the surprising finding that expression of genes controlling immune and inflammatory responses may play a causal role in promoting kidney damage, and suggest […]Continue Reading ...
THURSDAY, Nov. 1, 2018 — Intensive blood pressure (BP) control and fenofibrate use in patients with type 2 diabetes who are at high risk for cardiovascular disease may increase the risk for adverse kidney events, according to a study published in the Clinical Journal of the American Society of Nephrology to coincide with its presentation […]Continue Reading ...
This image shows a cross section of a kidney. Credit: Holly Fischer/Wikipedia Although there have been considerable reductions in disparities in adult kidney transplant outcomes in the United States, a new study found that disparities in long-term patient survival among pediatric kidney transplant recipients have worsened. The findings will be presented at ASN Kidney Week […]Continue Reading ...
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