leukemia – Medicalnewser.com

Researchers identify powerful inhibitor of epigenetic factors that promote acute myeloid leukemia

— November 28, 2018

Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit the dysregulated proteins. In the journal Angewandte Chemie, researchers report the discovery, design, and testing of potential drugs on the cellular level. The findings […]

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia
— November 16, 2018

While it has long been recognized that mutated gene NPM1 plays an important role in acute myeloid leukemia, no one has determined how the normal and the mutated forms of the protein NPM1 function. “It is one of the biggest enigmas in acute myeloid leukemia,” said Dr. Margaret Goodell, professor in the Center for Stem […]
Continue Reading ...
Low-fat diet increases cancer survival rate in mice, study finds
— November 10, 2018

Credit: CC0 Public Domain Something as simple as a change in diet can potentially help to increase the cancer survival rate of obese children with acute lymphoblastic leukemia, the most common childhood cancer, according to a new study by UCLA scientists. The research team, led by Dr. Steven Mittelman, chief of pediatric endocrinology at UCLA […]
Continue Reading ...
Scientists identify new target for battling deadly form of leukemia
— October 25, 2018

UT Southwestern scientists, working with colleagues at a sister institution in Houston, have identified a new target for battling a deadly form of leukemia. The findings raise the possibility of a novel treatment for this subtype of blood and bone marrow cancer – known as acute myeloid leukemia or AML – by attacking a harmful […]
Continue Reading ...
HU researchers develop new biological drug that may cure acute myeloid leukemia
— August 28, 2018

Acute myeloid leukemia is one of the most aggressive cancers. While other cancers have benefited from new treatments, there has been no encouraging news for most leukemia patients for the past 40 years. Until now. As published today in the scientific journal Cell, Professor Yinon Ben-Neriah and his research team at the Hebrew University of […]
Continue Reading ...
Scientists discover new way to predict healthy individuals at risk of developing AML
— July 11, 2018

July 10, 2018 An international team of leukemia scientists has discovered how to predict healthy individuals at risk of developing acute myeloid leukemia (AML), an aggressive and often deadly blood cancer. The findings, published today in Nature, illuminate the ‘black box of leukemia’ and answer the question of where, when and how the disease begins, […]
Continue Reading ...
Researchers complete genomic map of chronic lymphocytic leukemia
— May 23, 2018

By Sally Robertson, BScMay 23, 2018 Researchers from the University of Barcelona, August Pi i Sunyer Biomedical Research Institute and Hospital Clínic Barcelona have created a high-resolution map of the entire epigenome of chronic lymphocytic leukemia, the most common form of leukemia. Image Credit: Kateryna Kon/Shutterstock.com Comparing the map with one of healthy cells flagged […]
Continue Reading ...
Researchers discover new information related to rare form of leukemia
— April 20, 2018

April 20, 2018 International research consortium led by researchers from the University of Helsinki, Finland, discovered new information related to a rare form of leukemia called aggressive NK-cell leukemia. Potential new treatment options were found which are highly warranted as currently this disease usually leads to rapid death of patients. The study was published in […]
Continue Reading ...

St. Jude Hospital announces availability of largest collections of leukemia samples
— November 15, 2018

St. Jude Children’s Research Hospital today announced the availability of one of the world’s largest collections of leukemia samples from children and adults. The effort, called PROPEL (Public Resource of Patient-derived and Expanded Leukemias), aims to advance fundamental research on the biology of leukemia and to help develop cures by sharing unique patient-derived xenograft samples […]
Continue Reading ...
Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment
— November 1, 2018

A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins. Researchers found that when injected into mice that had […]
Continue Reading ...
FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia
— August 30, 2018

Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) accepted its supplemental Biologics License Application (sBLA) for Sprycel (dasatinib) in combination with chemotherapy for the treatment of pediatric patients with newly diagnosed Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL). The FDA action date is December 29, 2018. “Sprycel was […]
Continue Reading ...
Scientists discover key vulnerability of mixed lineage leukemia
— August 15, 2018

August 13, 2018 Childhood leukemia is a diagnosis that no family ever wants to endure. While the treatment of most types of leukemia has improved steadily over the years, a few specific types remain very difficult to treat. One of these is called “mixed lineage leukemia,” and for children affected by this cancer, their chance […]
Continue Reading ...
Moxetumomab Pasudotox Pivotal Data in Patients with Previously-Treated Hairy Cell Leukemia Presented at the 2018 ASCO Meeting
— June 11, 2018

June 2, 2018 — AstraZeneca and MedImmune, its global biologics research and development arm, today presented results from the Phase III (‘1053’) clinical trial (Abstract #7004) that evaluated moxetumomab pasudotox in 80 patients with relapsed or refractory hairy cell leukemia (HCL) who had received at least two prior lines of therapy.1 Moxetumomab pasudotox, an investigational […]
Continue Reading ...
Researchers identify protein crucial for leukemia’s aggressiveness
— April 28, 2018

April 27, 2018 Researchers have identified a protein critical for the aggressiveness of T-cell leukemia, a subtype of leukemia that afflicts children and adults. The identification of ubiquitin-fusion degradation 1 (UFD1) allows for better understanding what causes leukemia to progress and become highly aggressive and treatment-resistant, and may lead to a new treatment for this […]
Continue Reading ...
Scientists identify key genetic events responsible for initiating childhood leukemia
— April 7, 2018

April 6, 2018 The key genetic events responsible for initiating the early stages of a type of childhood leukemia have been identified by scientists at The Institute of Cancer Research, London. Insights into the ‘founder’ genetic mutation for this type of leukemia, present in all the cancer cells, could be used in the development of […]
Continue Reading ...

Researchers identify powerful inhibitor of epigenetic factors that promote acute myeloid leukemia

Researchers unravel mystery of NPM1 protein in acute myeloid leukemia

Low-fat diet increases cancer survival rate in mice, study finds

Scientists identify new target for battling deadly form of leukemia

HU researchers develop new biological drug that may cure acute myeloid leukemia

Scientists discover new way to predict healthy individuals at risk of developing AML

Researchers complete genomic map of chronic lymphocytic leukemia

Researchers discover new information related to rare form of leukemia

St. Jude Hospital announces availability of largest collections of leukemia samples

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

FDA accepts Bristol-Myers Squibb’s application for Sprycel for treating pediatric leukemia

Scientists discover key vulnerability of mixed lineage leukemia

Moxetumomab Pasudotox Pivotal Data in Patients with Previously-Treated Hairy Cell Leukemia Presented at the 2018 ASCO Meeting

Researchers identify protein crucial for leukemia’s aggressiveness

Scientists identify key genetic events responsible for initiating childhood leukemia

Categories

Recent Posts