Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualized serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely melanopsin. As a result, they were able to switch the receptor on and off using light; it also acted like a sensor indicating via […]Continue Reading ...
A team of scientists from the National University of Science and Technology “MISIS”, the Moscow Technological University (MIREA) and the Pirogov Russian National Research Medical University has experimentally proved the effectiveness of the formerly suggested “light” method in oncotherapy. In a series of laboratory preclinical tests, the tumor growth stopped in 70% of mice, treated […]Continue Reading ...
An interview with Dr Claudia Jaffe, conducted at SfN by Alina Shrourou, BSc. What are illuminators and how do they enhance microscopy and bioanalysis? Light plays a critical role in our ability to generate high resolution images and to detect in a quantitative manner. In terms of image quality, it defines the contrast, resolution and […]Continue Reading ...
Researchers from the Washington University School of Medicine have developed an implantable device that could one day help people with bladder problems, without the need for electronic stimulators or medication. Magic Mine | Shutterstock As reported in the journal Nature, the tiny soft device detects overactivity in the bladder and uses light from integrated LEDs […]Continue Reading ...
Dec 11 2018 At the 2018 American Society of Cell Biology Meeting (ASCB), Bruker today announced the launch of the new Luxendo InVi SPIM AIM next-generation lattice light-sheet microscope, which features an advanced illumination module (AIM) for lowest phototoxicity light-sheet fluorescence microscopy of live samples. Leveraging the general benefits of single-plane illumination microscopy (SPIM) with […]Continue Reading ...
Image of pyramidal neurons in mouse cerebral cortex expressing green fluorescent protein. The red staining indicates GABAergic interneurons. (Source PLoS Biology). Image via Wikimedia Commons. By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network—even an entire brain. Now one of the […]Continue Reading ...
By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network – even an entire brain. Now one of the pioneers of ‘optogenetics’ and colleagues have created two new tools – protein pores which when illuminated allow Ca2+ into cells or K+ out […]Continue Reading ...
Using light-sensitive proteins, researchers study the brain’s reward memory response In new pre-clinical research, scientists at the University of Maryland School of Medicine (UMSOM), led by Scott Thompson, PhD, Professor of Physiology, have identified changes in brain activity linked to the pleasure and reward system. The research, published in the journal, Nature, provides news insights […]Continue Reading ...
In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands. This property is known as “chirality” and molecules with different chirality are called enantiomers. Enantiomers can exhibit entirely different chemical or biological properties, and separating them is a major […]Continue Reading ...
University of Arizona biomedical engineering professor Philipp Gutruf is first author on the paper Fully implantable, optoelectronic systems for battery-free, multimodal operation in neuroscience research, published in Nature Electronics. Optogenetics is a biological technique that uses light to turn specific neuron groups in the brain on or off. For example, researchers might use optogenetic stimulation […]Continue Reading ...
An oscillating light on a sensor helps scientists see individual cells under a microscope and how they behave. Credit: University of York Scientists at the University of York have developed a new technique that uses light to understand how cells communicate in human disease. All cells in the human body communicate with each other by […]Continue Reading ...
Pulling off a Band-Aid may soon get a lot less painful. Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) and Xi’an Jiaotong University in China have developed a new type of adhesive that can strongly adhere wet materials — such as hydrogel and living tissue — and be easily […]Continue Reading ...
Oct 25 2018 AXT has recently been appointed the local distributor for Phi Optics, an innovative developer of Quantitative Phase Imaging (QPI) solutions for live cell and tissue microscopy. Phi Optics’ modular solutions have been designed as simple add-ons for existing inverted light microscopes giving them detailed analytical capabilities. Phi Optics GLIM Gradient Light Interference […]Continue Reading ...
A new study is the first population-based investigation to report a significant association between artificial, outdoor light exposure at night and insomnia, as indicated by older adults’ use of hypnotic drugs. Results show that increasing nighttime levels of artificial, outdoor light exposure, stratified by quartile, were associated with an increased prevalence of hypnotic prescriptions and […]Continue Reading ...
When you shine a beam of light on your hand, you don’t feel much, except for a little bit of heat generated by the beam. When you shine that same light into a world that is measured on the nano- or micro scale, the light becomes a powerful manipulating tool that you can use to […]Continue Reading ...
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