FINDINGS Scientists at the UCLA Jonsson Comprehensive Cancer Center have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes tumor growth. The finding provides evidence that SGLT2 may be a novel biomarker that scientists can use to […]Continue Reading ...
The first-ever randomized controlled trial on babies with cystic fibrosis (CF) has found that treatment with inhaled hypertonic saline can improve breathing and lung health. Evgeny Atamanenko | Shutterstock The study involved 40 babies, enrolled at a mean age of three months. The babies were randomly assigned to hypertonic saline (6.8% saline) or isotonic saline […]Continue Reading ...
Cells live in complex communities called microenvironments, where many different types of cells interact with one another. In cancer, the microenvironment is a place where cancer cells and healthy cells interact. Oliver’s study outlines a lung tumors’ influence on immune cells in its microenvironment. Represented in illustration A is a lung tumor. The lung tumor’s […]Continue Reading ...
Lung CA seen on CXR. Credit: James Heilman, MD/Wikipedia Use of angiotensin converting enzyme inhibitor drugs (ACEIs) to lower blood pressure is associated with an increased risk of lung cancer compared with use of another group of blood pressure drugs called angiotensin receptor blockers (ARBs), finds a study in The BMJ today. The risk is […]Continue Reading ...
Lungs are vital organs required for the uptake of oxygen in exchange for carbon dioxide. However, the enormous complexity of the respiratory organ is often underestimated and deserves a closer look: A broad range of specialized cells work closely together to ensure the proper functioning of the lung and provide the vital gas exchange. Among […]Continue Reading ...
Credit: CC0 Public Domain Assisted ventilation is crucial to support very preterm babies, however the treatment often leads to chronic lung disease. While the survival of preterm babies has increased over the past 30 years, rates of chronic lung disease have remained static. Now a team of researchers has found the type of injury caused […]Continue Reading ...
FDA Approves Vizimpro (dacomitinib) for the First-Line Treatment of Patients with EGFR-Mutated Metastatic Non-Small Cell Lung Cancer September 27, 2018 – Pfizer Inc. (NYSE:PFE) today announced that the U.S. Food and Drug Administration (FDA) has approved Vizimpro [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) […]Continue Reading ...
FRIDAY, Sept. 7, 2018 — Machine learning approaches to metabolite analysis can predict key pathways contributing to lung function loss associated with World Trade Center Lung Injury (WTC-LI), according to a small study published online Sept. 3 in BMJ Open Respiratory Research. George Crowley, from New York University in New York City, and colleagues quantified […]Continue Reading ...
The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients per year. But while drugs like trastuzumab and lapatinib have proven effective in silencing the action of […]Continue Reading ...
A study has shown that the showerheads contain slime that can be home to potentially dangerous bacteria which lead to severe lung disease. Mycobacterial bacteria are responsible for lung diseases explain experts. The study titled, “Ecological Analyses of Mycobacteria in Showerhead Biofilms and Their Relevance to Human Health”, is published in the latest issue of […]Continue Reading ...
An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis. The findings are published in the current issue of the New England Journal of Medicine. “By uncovering this link in the genetic background between […]Continue Reading ...
Oct 12 2018 The adult lung consists of different, highly specialized cell types that are protected by a variety of immune cells. How these immune cells migrate to the lungs during development and after birth, and how these cells influence each other, is poorly understood. Using advanced single cell sequencing methods, researchers of the Weizmann […]Continue Reading ...
Lung cancer is the leading cause of cancer death among men and women. About 85 percent of lung cancers are non-small cell lung cancer. For a handful of these patients, therapies that target specific genetic mutations are effective. But for the majority of non-small cell lung cancer patients, targeted therapies are limited and many patients […]Continue Reading ...
Sep 19 2018 Procedure could help doctors treat disease before it spreads – without drastic surgery A new minimally invasive surgery could provide a breakthrough in treating early-stage lung cancer, based on a review of some of the first patients to receive the procedure. X-ray images of lung samples with the microcoil. (Courtesy: Cleveland Clinic) […]Continue Reading ...
A scientific team led by Cedars-Sinai has been awarded $12 million from the National Institutes of Health (NIH) to investigate two deadly lung conditions: idiopathic pulmonary fibrosis and chronic lung allograft dysfunction. Idiopathic pulmonary fibrosis, which scars lung tissue and obstructs breathing, affects more than 100,000 people in the U.S. While the course of the […]Continue Reading ...
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