Mayumi Fajita, MD, PhD and colleagues show that CDK1 interacts with Sox2 to keep cancer stem cells ‘stemmy’. Credit: University of Colorado Cancer Center CDK1 is a “normal” protein—its presence drives cells through the cycle of replication. And MHC Class I molecules are “normal” as well—they present bits of proteins on the surfaces of cells […]Continue Reading ...
CDK1 is a “normal” protein – its presence drives cells through the cycle of replication. And MHC Class I molecules are “normal” as well – they present bits of proteins on the surfaces of cells for examination by the immune system. But a University of Colorado Cancer Center study published in the journal Cancer Research […]Continue Reading ...
Cancer immunotherapy — efforts to boost a patient’s own immune system, allowing it to better fight cancer cells on its own — has shown great promise for some previously intractable cancers. Yet immunotherapy doesn’t work for everyone, for reasons that aren’t always clear. Most research and new therapies in this field have been focused on […]Continue Reading ...
BLS II is led to by way of mutations within the CIITA, RFX5, RFXANK, or RFXAP gene. Every of those genes supplies directions for creating a protein that performs a job in controlling the job () of genes referred to as MHC elegance II genes. Transcription is step one within the manufacturing of proteins, and […]Continue Reading ...
Cancer immunotherapy is an attractive and relatively newer method of treating cancer by enhancing the combat-readiness of the host immune system against cancer cells. It has succeeded with some refractory tumors. However, it doesn’t always work, and the question remains, why not? CI Photos | Shutterstock Researchers in this field have mostly examined the role […]Continue Reading ...
Credit score: CC0 Public Area For almost 20 years, Tatyana Golovkina, PhD, a microbiologist, geneticist and immunologist on the College of Chicago, has been operating on a specifically thorny drawback: Why are some other people and animals ready to fend off power viral infections whilst others cannot? Mice from a pressure referred to as I/LnJ […]Continue Reading ...
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