Dec 3 2018 Multiple components of the nuclear pore complex and nuclear import machinery enable a protein called human myxovirus resistance 2 (MX2) to inhibit HIV-1 infection, according to a study published November 29 in the open-access journal PLOS Pathogens by Michael Malim of King’s College London, and colleagues. Antibody staining and light microscopy demonstrate […]Continue Reading ...
The integrity of the genome relies on the ability of the cells to build and maintain a well-defined boundary between the nuclear compartment and the cytoplasm, known as the nuclear envelope. A new study, led by Leandro Ventimiglia in Professor Juan Martin-Serrano’s lab of the School of Immunology & Microbial Sciences, characterizes the cellular machinery […]Continue Reading ...
Sep 24 2018 The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is pleased to announce the recipients of the 2018-2020 SNMMI Wagner-Torizuka Fellowship. This one- or two-year fellowship, founded in 2008 by the late Henry N. Wagner, Jr., MD, and the late Kanji Torizuka, MD, PhD, is designed to provide extensive training and experience […]Continue Reading ...
Researchers from the University of Illinois have developed a way of mapping the positions of genes within cells to understand more about how the genome is organized. Image Credit: Anatomy Insider / Shutterstock As reported in the Journal of Cell biology, Yu Chen and colleagues have used a technique called tyramide signal amplification sequencing (TSA-Seq) […]Continue Reading ...
June 22, 2018 The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings – so-called nuclear pores. The outer nuclear envelope is also […]Continue Reading ...
Assistant Professor Maximiliano D’Angelo, Ph.D. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP) Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus—they play an essential role in the survival of T cells. A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers […]Continue Reading ...
WEDNESDAY, March 28, 2018 — The United States is ill-prepared to handle the myriad medical emergencies that would be unleashed by a nuclear attack by terrorists, a special report warns. Instead, the absolute best strategy is to prevent such an attack from happening in the first place, said report author Dr. Robert Gale. He’s a […]Continue Reading ...
March 15, 2018 Two University of Houston scientists are reporting that defects in a portion of the brain’s hippocampus, called the dentate gyrus, is regulated by the nuclear receptor LXRβ (Liver X receptor Beta). The dentate gyrus, or DG, is responsible for emotion and memory and is known to be involved in autism spectrum disorders […]Continue Reading ...
TRIUMF, Canada’s particle accelerator center, and Canadian Nuclear Laboratories (CNL), Canada’s premier nuclear science and technology organization, are pleased to announce that they have agreed to pursue a strategic partnership around the commercial production of Actinium-225, a rare medical isotope that has the potential to serve as the basis of new ground-breaking cancer treatments. An […]Continue Reading ...
If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren’t necessarily better: some cancer cells contain a dramatic excess of nuclear pores. Salk Institute researchers reported on September 18, 2018, in the journal Genes & Development that they have devised a […]Continue Reading ...
June 29, 2018 A tremendous amount of genetic material must be packed into the nucleus of every cell–a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be called upon so that the genes encoded in them can be “turned on” or expressed […]Continue Reading ...
May 29, 2018 A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases – and possibly even turn back the clock on aging itself. The new finding from the University of Virginia School of Medicine suggests that fatty liver […]Continue Reading ...
May 8, 2018 Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus-;they play an essential role in the survival of T cells. A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers describes how a specific nuclear pore component is critical for […]Continue Reading ...
March 16, 2018 Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature’s solution is a massive–by molecular standards–cylindrical configuration known as the nuclear pore complex, […]Continue Reading ...
July three, 2017 Researchers on the College of Melbourne have demonstrated a method to discover nuclear spins in molecules non-invasively, offering a brand new software for biotechnology and fabrics science. Essential analysis in drugs and biology is dependent upon nuclear magnetic resonance (NMR) spectroscopy, however till now, it’s been restricted in spatial answer and normally […]Continue Reading ...
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