Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world. The method of analysis, which has been published in the journal Molecular Cell, can also provide in-depth […]Continue Reading ...
A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome. The study can bring new ways to understand the […]Continue Reading ...
A Montana State University doctoral student who is working on a way to improve a neuroscience tool that uses fluorescent proteins found in some jellyfish and coral has received a grant that will help fund her work. The National Institute of Neurological Disorders and Stroke awarded a three-year F31 fellowship grant to Rosana Molina, a […]Continue Reading ...
Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their “coworkers.” Now, researchers reporting in ACS’ journal Analytical Chemistry have developed […]Continue Reading ...
Researchers working to understand the biochemistry of cataract formation have made a surprising finding: A protein that was long believed to be inert actually has an important chemical function that protects the lens of the eye from cataract formation. The lens is made up of cells packed with structural proteins called crystallins. Crystallins within each […]Continue Reading ...
Researchers at the University of Freiburg have discovered a mechanism within cells that enables proteins to be delivered into the mitochondria. UGREEN 3S | Shutterstock Mitochondria are the organelles responsible for many essential cellular processes, including providing energy for metabolism. Defects that occur in the biogenesis or function of the mitochondria can cause serious neurological […]Continue Reading ...
Monitoring cancer can often be an intrusive and exhausting process for patients. But with Brigham Young University chemistry professor Ryan Kelly’s new research, there is hope for a simpler way: No more biopsies. No more spinal taps. Instead, patients may be able to take a simple blood test to diagnose, monitor and tailor appropriate therapies […]Continue Reading ...
The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer’s, Huntingdon’s and Parkinson’s work has taken major steps forward in the last 12 months, thanks to a revolution in a powerful microscopy technique used by scientists. High-powered microscopes using electrons instead of light to ‘see’ the actual shape of […]Continue Reading ...
An international team coordinated by the Interdisciplinary Research Structure in Biotechnology and Biomedicine (ERI BioTecMed) of the University of Valencia has proved how the folding of membrane proteins begins before they are inserted into biological membranes, a fact that has been central to the biochemical research for decades. The study, published in the Nature Communications […]Continue Reading ...
Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating […]Continue Reading ...
Dec 6 2018 Methodology could lead to identification of new markers for cancers, other diseases Researchers at Johns Hopkins Medicine have developed a new molecular tool they call EXoO, which decodes where on proteins specific sugars are attached–a possible modification due to disease. The study, published in issue 14 of Molecular Systems Biology, describes the […]Continue Reading ...
Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit the dysregulated proteins. In the journal Angewandte Chemie, researchers report the discovery, design, and testing of potential drugs on the cellular level. The findings […]Continue Reading ...
A recent study has found that prion proteins that cause a deadly brain disease may enter the body via the eyes. Researchers at the National Institute of Allergy and Infectious Diseases, the University of California at San Diego and UC-San Francisco could also detect prion protein infection by looking at the eyes, the study shows. […]Continue Reading ...
In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs. The findings, published in Molecular and Cellular Proteomics, are especially important since the microbe, […]Continue Reading ...
Fujitsu Laboratories Ltd., the Insight Centre for Data Analytics, a data analytics research institution based in Ireland, and Fujitsu (Ireland) Limited today announced the development of a technology that makes it possible to predict large volumes of unknown chemical reactions, about twice as many as the conventional procedure. In serious diseases, including cancer, it is […]Continue Reading ...
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