THURSDAY, Sept. 20, 2018 — Preoperative statin therapy is associated with higher long-term survival following abdominal aortic aneurysm (AAA) repair, according to a study published in the August issue of the Journal of Vascular Surgery. Thomas F.X. O’Donnell, M.D., from the Beth Israel Deaconess Medical Center in Boston, and colleagues used data from the Vascular […]Continue Reading ...
According to data from the Centers for Disease Control and Prevention, nearly half of U.S. adults have gum disease. Harmful plaque bacteria can hide in crevices below the gum line. When left untreated, the plaque bacteria can break down enamel and cause permanent damage. New Crest Gum & Enamel Repair™, a specially designed paste, focuses […]Continue Reading ...
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme. Mutations in the gene which codes for DDX11 are known to be implicated in Warsaw Breakage Syndrome. They showed that DDX11 plays an important role in DNA repair, and […]Continue Reading ...
Credit: CC0 Public Domain A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication. In a study published in Nature Cell Biology, the team from the Wellcome/Cancer Research […]Continue Reading ...
July 25, 2018 A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication. In a study published in Nature Cell Biology, the team from the Wellcome/Cancer Research UK […]Continue Reading ...
A depiction of the double helical structure of DNA. Its four coding units (A, T, C, G) are color-coded in pink, orange, purple and yellow. Credit: NHGRI Proteins commonly known as BRCA—short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating […]Continue Reading ...
June 13, 2018 Scientists at the University of Sheffield have discovered what keeps the perfect balance of breaks and repairs in our DNA – something which could help improve the success of chemotherapy and combat neurodegeneration associated with aging. Our genome, where precious genetic information is stored, is challenged with thousands of breaks every day. […]Continue Reading ...
June 11, 2018 DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and […]Continue Reading ...
Lack of dysferlin is associated with increased lipid mobility in the limb girdle muscular dystrophy type 2B (LGMD2B) cell membrane, which is further increased by injury and prednisolone treatment, causing failure of these cells to undergo repair. By contrast, vamorolone treatment stabilizes the LGMD2B muscle cell membrane to near healthy cell level, enabling repair of […]Continue Reading ...
Aug 24 2018 Through a study of roundworm nerve cells with severed axons, researchers at Nagoya University showed that a signaling cascade that normally functions in promoting the phagocytosis of apoptotic cells also acts in inducing axon regeneration. The findings shed light on a fundamental feature of nerve repair, which is limited in the central […]Continue Reading ...
July 30, 2018 An international research team under the co-direction of the University of Bern and the Netherlands Cancer Institute (NKI) has discovered various mechanisms of resistance to cancer therapy. The findings help researchers to understand the self-repair of cancer cells after a therapy and thus help to fight resistant tumors more efficiently. The DNA […]Continue Reading ...
July 19, 2018 Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer. Their study, published in Nature today (Wednesday), uncovered a brand new protein complex in cells that shields broken DNA ends and controls the way in which it is […]Continue Reading ...
June 21, 2018 The cell has its own paramedic team and emergency room to aid and repair damaged DNA, a new USC Dornsife study reveals. The findings are timely, as scientists are delving into the potential of genome editing with the DNA-cutting enzyme, CRISPR-Cas9, to treat diseases or to advance scientific knowledge about humans, plants, […]Continue Reading ...
June 13, 2018 Proteins commonly known as BRCA – short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the BRCA repair system is disabled in cancer cells, the cells simply turn to backup repair mechanisms and adapt […]Continue Reading ...
Credit: Georgia State University A new group of proteins called cytokines, critical for antimicrobial activity and repairing the damaged intestinal tissue found in inflammatory bowel disease (IBD), has been discovered by researchers in a study led by Georgia State University. The research team examined acute intestinal disease in the colons of mice and found a […]Continue Reading ...
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