Apr 8 2019 A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy. Injections of synthetic DNA encoding the potent anti-Zika monoclonal antibody ZK190 resulted in high production of ZK190 for weeks to months, effectively controlling infection in all animals. The new platform for […]Continue Reading ...
Transmission electron microscope image of negative-stained, Fortaleza-strain Zika virus (red), isolated from a microcephaly case in Brazil. The virus is associated with cellular membranes in the center. Credit: NIAID The Zika virus is widely known for causing microcephaly and other brain defects in the fetuses of pregnant, infected women. Currently, there are no approved antiviral […]Continue Reading ...
In the Americas, primate species likely to harbor Zika – and potentially transmit the virus – are common, abundant, and often live near people. So reports a new study published today in Epidemics. Findings are based on an innovative model developed by a collaborative team of researchers from Cary Institute of Ecosystem Studies and IBM […]Continue Reading ...
Researchers at Duke-NUS Medical School and their colleagues have identified a surprising interaction between dengue and Zika viruses that sheds lights on the significant fetal brain abnormalities linked to Zika virus. The researchers found that fetal mouse brain damage was much worse if the mothers infected with Zika also had dengue antibodies. They further determined […]Continue Reading ...
Women who have previously been infected with dengue virus may be at risk for increased damage to their fetuses and placentas if they should later become infected with the Zika virus, researchers from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai report. This study is the first to report a […]Continue Reading ...
Jan 25 2019 Immune cells called CD4+ T cells could be important mediators of protection against the Zika virus, according to a study published January 24 in the open-access journal PLOS Pathogens by Sujan Shresta of the La Jolla Institute for Allergy and Immunology, and colleagues. The findings support vaccine strategies that induce a protective […]Continue Reading ...
Jan 23 2019 Previous infection with dengue virus may protect children from symptomatic Zika, according to a study published January 22 in the open-access journal PLOS Medicine by Eva Harris of the University of California, Berkeley, and colleagues. Credit: AFMC Public Affairs, U.S. Air Force Zika virus emerged in northeast Brazil in 2015 and spread […]Continue Reading ...
Millions of people have contracted Zika and chikungunya virus infections since the outbreaks that have been striking Latin America since 2013. Particularly Zika-related malformations in newborns warrant reliable diagnostics. DZIF scientists from the Charité – Universitätsmedizin Berlin demonstrate the problems with the currently available diagnostics, particularly for Zika virus detection, and develop combined testing methods […]Continue Reading ...
The Zika virus is widely known for causing microcephaly and other brain defects in the fetuses of pregnant, infected women. Currently, there are no approved antiviral therapies specifically designed to treat Zika, but researchers at the Advanced Science Research Center (ASRC) at The Graduate Center of The City University of New York, Hunter College, and […]Continue Reading ...
Mar 6 2019 Women infected with Zika virus early in pregnancy are almost 17 times more likely to have a child with microcephaly, according to a study published this week in PLOS Medicine by Oliver Brady of the London School of Hygiene & Tropical Medicine, UK, and colleagues. Credit: zefe, Pixabay In 2015, greater than […]Continue Reading ...
The circulation of the dengue virus for the past sixty years in South-East Asia is relatively well known. For Zika, the situation is much less clear. In an attempt to shed light on Zika circulation, scientists from the Institut Pasteur and the CNRS, in collaboration with US teams and the Thai National Institute of Health, […]Continue Reading ...
A collaboration of scientists including Professor Jean Patterson, Ph.D., of Texas Biomedical Research Institute, is working on a new way to detect Zika virus that will help guide clinicians in their treatment of patients with the disease. The test uses optofluidic chips to screen bodily fluids (blood, urine, semen) for the presence of the virus. […]Continue Reading ...
A prior dengue virus infection could protect children from symptomatic Zika virus infection, according to a study by an international group of researchers including those from the University of Michigan and the University of California, Berkeley. “We don’t think that that dengue immunity protects from being infected (with Zika), or at least it doesn’t look […]Continue Reading ...
Children with a history of prior dengue virus infection had a significantly lower risk of being symptomatic when infected by Zika virus, according to a study in Nicaragua of more than 3,000 children aged 2 to 14 years. Experts have worried that prior dengue virus infection could exacerbate severe Zika disease. However, the new findings, […]Continue Reading ...
A cellular protein that interacts with invading viruses appears to help enable the infection process of the Zika virus, according to an international team of researchers who suggest this protein could be a key target in developing new therapies to prevent or treat Zika virus infection. Scientists first isolated Zika, a member of the Flaviviridae […]Continue Reading ...
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