Breaking News
February 19, 2018 - ID Break: Clean Hands, Fewer Abx; $11 Million HIV Cure?; MenB Vax for Kids
February 19, 2018 - Patient exposure to X-rays depends on how dentists are paid
February 19, 2018 - FDA approves first treatment to reduce risk of NSCLC progression
February 19, 2018 - FDA Expands Approval of Imfinzi (durvalumab) to Reduce the Risk of Non-Small Cell Lung Cancer Progressing
February 19, 2018 - D.C. Week: Congress Passes Spending Bill
February 19, 2018 - Heart-muscle patches made with human cells improve heart attack recovery
February 19, 2018 - FDA Approves First Blood Test to Detect Concussions
February 19, 2018 - Survival Bump in Bladder Cancer with Keytruda
February 18, 2018 - Scientists describe the mechanism of heart regeneration in the zebrafish
February 18, 2018 - Scientists uncover the structure of microtubule motor proteins
February 18, 2018 - Light-activated cancer drugs without toxic side effects are closer to becoming reality
February 18, 2018 - Pioneering research could provide novel insight into how genomic information is read
February 18, 2018 - Pearls From: David Putrino, PhD
February 18, 2018 - Researchers uncover how cancer stem cells drive triple-negative breast cancer
February 18, 2018 - Morning Break: Anti-Anti-Vaxxers; Private Piercings Prohibited; A Case for Pelvic Massage
February 18, 2018 - Lower-dose radiation effective, safe for HPV+ head and neck cancer after induction chemo
February 18, 2018 - Specialist residential service for adults with autism opens in Swansea
February 18, 2018 - FDA Moves to Limit Loperamide Doses per Package
February 18, 2018 - Alcohol use disorder – Genetics Home Reference
February 18, 2018 - Autism might be better detected using new two-minute questionnaire
February 18, 2018 - Hand hygiene-intervention practices may reduce risk of infection among nursing home patients
February 18, 2018 - Researchers develop most sophisticated mini-livers to date
February 18, 2018 - Obamacare Helped More Young Women Get Prenatal Care: Study
February 18, 2018 - School-Based Program Fails to Dent Kids’ Obesity
February 18, 2018 - Research compares neural activity in children with and without autism spectrum disorder
February 18, 2018 - Poor fitness levels increase the risk dementia, concludes study
February 18, 2018 - Risk Score May Reveal if Kids are Victims of Ill-Treatment
February 18, 2018 - Adding Folic Acid to Corn Masa Flour May Prevent Birth Defects
February 18, 2018 - Acute treatment suppresses posttraumatic arthritis in ankle injury
February 18, 2018 - A Role for Budesonide in Autoimmune Hepatitis?
February 18, 2018 - Lupus patients exhibit altered cell proteins, a discovery with potential implications for diagnostics
February 18, 2018 - Muscle plays vital role in regulating heat loss from the hands
February 18, 2018 - High-tech brain scans can provide new way to define intelligence
February 18, 2018 - Study reveals the association between ultra-processed foods and cancer
February 18, 2018 - Prescription Opioid Use Tied to Higher Pneumonia Risk
February 18, 2018 - A non-invasive method to detect Alzheimer’s disease
February 18, 2018 - Deletion of specific enzyme leads to improvement in memory and cognitive functions
February 18, 2018 - Amyloid protein may be transmitted through neurosurgical instruments, study suggests
February 18, 2018 - Electric brain signals of males and females show differences
February 18, 2018 - American Heart Association commends McDonald’s for offering healthier menu in kids’ meals
February 18, 2018 - Parents Find Kids’ Weight Report Cards Hard to Swallow
February 18, 2018 - Does a Financial Conflict of Interest Ever Expire?
February 18, 2018 - Exercise can improve Alzheimer’s symptoms
February 18, 2018 - Scientists develop green chemistry method to improve pharmaceutical manufacturing efficiency
February 17, 2018 - ‘A Time Clock to a Tissue Clock’ for Acute Stroke Care
February 17, 2018 - Cancer Care Gets Personal | NIH News in Health
February 17, 2018 - Do more youth use or do youth use more?
February 17, 2018 - Eating faster linked to obesity
February 17, 2018 - Who’s Still Smoking? ACS Report Highlights Most Vulnerable Adults
February 17, 2018 - Study of smoking and genetics illuminates complexities of blood pressure
February 17, 2018 - Study reveals new link between bone cells and blood glucose level
February 17, 2018 - Children with reading challenges may have lower than expected binocular vision test results
February 17, 2018 - Mass Shootings Trigger Change for Emergency Medicine
February 17, 2018 - ECMO helps revive woman thought to be drowned
February 17, 2018 - Learning stress-reducing techniques may benefit people with epilepsy
February 17, 2018 - Shedding Pounds Before Weight-Loss Surgery a Smart Move
February 17, 2018 - FDA Approves New Cystic Fibrosis Drug Combo
February 17, 2018 - Augmented Reality helps surgeons to ‘see through’ tissue and reconnect blood vessels
February 17, 2018 - Emotional state affects operation of the entire brain instead of being restricted to specific regions
February 17, 2018 - Apalutamide Slows Metastasis in Prostate Cancer
February 17, 2018 - Kids’ well visits linked to lower appendicitis complications
February 17, 2018 - New NK cell-based immunotherapy effective against several types of leukemia
February 17, 2018 - Producing Super-Swelled Lyotropic Crystals for Drug Development
February 17, 2018 - Pfizer Receives Breakthrough Therapy Designation from FDA for PF-04965842, an oral JAK1 Inhibitor, for the Treatment of Patients with Moderate-to-Severe Atopic Dermatitis
February 17, 2018 - Molecular Imaging Flags Risk of AAA Rupture
February 17, 2018 - Researchers identify risk factors for sleep apnea during pregnancy
February 17, 2018 - More work required to find the right drug dosage for pediatric patients
February 17, 2018 - Factors ID’d That Predict RA Remission with Etanercept
February 17, 2018 - A handout or a hand up? How we judge others guides how we help others
February 17, 2018 - ACR receives grant to focus on projects that reduce health disparities
February 17, 2018 - Pimavanserin Might Be Safer Alternative to Ease Dementia Psychosis
February 17, 2018 - Risks of Lung Screening Seen Outweighing Benefits in Many with Smoking History
February 17, 2018 - The impact of Hurricane Harvey on pregnant moms
February 17, 2018 - Gene editing tool used to detect cancer
February 17, 2018 - Researchers detail molecular atlas of cells that form brain’s blood vessels
February 17, 2018 - TUM scientists observe formation of myelin sheaths around nerve fibers
February 17, 2018 - Worst Flu Season Yet? | Medpage Today
February 17, 2018 - Finding the root cause of bronchiolitis symptoms
February 17, 2018 - Climbing stairs reduces hypertension and strengthens muscles
February 17, 2018 - Nature paper unveils bacterial division
First large-scale malaria vaccine trials for Africa (Replace)

First large-scale malaria vaccine trials for Africa (Replace)

image_pdfDownload PDFimage_print
Credit score: CDC

A brand new malaria vaccine shall be examined on a big scale in Kenya, Ghana and Malawi, the Global Well being Group mentioned Monday, with 360,000 youngsters to be vaccinated between 2018 and 2020.

The injectable vaccine RTS,S may provide restricted coverage in opposition to a illness that killed 429,000 other folks international in 2015, with 92 % of sufferers in Africa and two-thirds of them youngsters below 5.

“The chance of a malaria vaccine is excellent information. Data accumulated within the pilot will lend a hand us make choices at the wider use of this vaccine,” mentioned Dr Matshidiso Moeti, the WHO’s regional director for Africa.

The vaccine will have to be used along different preventative measures comparable to mattress nets, pesticides, repellents and anti-malarial medication, the WHO mentioned.

“Mixed with current malaria interventions, this kind of vaccine would have the prospective to avoid wasting tens of hundreds of lives in Africa,” Moeti mentioned.

“This vaccine is a weapon among others, it is among the equipment at our disposal,” she added.

The vaccine, often referred to as Mosquirix, has been evolved via the British pharmaceutical massive GlaxoSmithKline (GSK) in partnership with the PATH Malaria Vaccine Initiative, and the large-scale three-country pilot will check it on youngsters elderly 5 to 17 months.

The drug handed earlier clinical trying out—together with a segment 3 medical trial between 2009 and 2014—and was once authorized for the pilot programme in 2015.

‘Large affect’

The purpose of the trial is to evaluate the effectiveness of the vaccine as neatly the feasibility of its supply to populations in danger as 4 successive doses will have to be given on a strict timetable.

The immunisation cycle isn’t in sync with regimen youth inoculations in opposition to illnesses comparable to hepatitis, measles and meningitis, with injections required at 5 months, six months, seven months and two years.

Signs of malaria come with fever, muscle ache and headache in addition to vomiting and diarrhoea.

Whilst RTS,S does no longer promise complete coverage in opposition to the mosquito-borne illness it’s among the finest doable vaccine to this point evolved lowering the collection of hospitalisations and blood transfusions.

Malaria episodes lowered via 40 % in exams on 15,000 other folks in seven nations over 5 years of medical trials, and may just due to this fact save loads of hundreds of lives.

“It is an efficacy charge which is reasonably low, however given the quantity of affected other folks, the affect shall be massive,” mentioned Mary Hamel, who’s coordinating the vaccine’s implementation programme.

“There shall be different vaccines and they will be extra environment friendly, however within the intervening time, this will likely have an important affect.”

Moeti emphasized that whilst the dream is “a vaccine that replaces the whole thing”, insecticide-treated mattress nets stay among the finest coverage in opposition to malaria, which stay, “in this day and age, our most powerful preventive weapon”.

Kenya, Ghana and Malawi have been decided on for the trial as a result of malaria charges are top and they’ve an extended historical past of use of mattress nets and different interventions.

The huge-scale pilot is the most recent step in many years of labor searching for to eliminate malaria with the numbers death falling just about two-thirds because the flip of the century.


Discover additional:
Malaria vaccine loses effectiveness over a number of years: learn about

Tagged with:

About author

Related Articles