Breaking News
March 21, 2018 - Flu Season Finally Slowing Down
March 21, 2018 - Mixed Results for Shorter DAPT in ACS Patients
March 21, 2018 - Scientists discover fish scale-derived collagen effective for healing wounds
March 21, 2018 - Genomics England announces new partnership to improve efficiency of next-generation sequencing analysis
March 21, 2018 - Adjuvant AC chemotherapy found to be effective in treating HRD-positive breast cancer patients
March 21, 2018 - Researchers identify new treatment targets for lung diseases using big data
March 21, 2018 - Alzheimer’s disease on the rise
March 21, 2018 - Two Agents Equal as Pretreatment for Adrenal Tumor Surgery
March 21, 2018 - ‘Icebreaker’ protein opens genome for T cell development, researchers find
March 21, 2018 - Women in medicine shout #Metoo about sexual harassment at work
March 21, 2018 - Mother’s pre-pregnancy waist size may be linked to child’s autism risk
March 21, 2018 - Second hand marijuana smoke can cause serious damage
March 21, 2018 - International study shows benefits of using MRI at the start of prostate cancer diagnosis
March 20, 2018 - Santhera Reports Outcome of Exploratory Trial with Idebenone in PPMS Conducted at the NIH
March 20, 2018 - ECG Patch Ups At-Home Afib Diagnosis in mSToPS Trial
March 20, 2018 - ROS-scavenging nanozymes for anti-inflammation therapeutics
March 20, 2018 - Genomics England announces appointment of global genomics pioneer as first CEO
March 20, 2018 - Test flight at German Aerospace Center in Cologne demonstrates functionality of deficopter
March 20, 2018 - Music therapy helps treat combat-related psychological injuries in military personnel
March 20, 2018 - Innovative psychotherapeutic treatment protocol for obsessive-compulsive disorders
March 20, 2018 - Weight loss after lap-band surgery alleviates arthritic knee pain
March 20, 2018 - New diabetes drug may help obese people shed body weight
March 20, 2018 - Novel Peanut OIT a Winner in Phase III Trial
March 20, 2018 - Can gene therapy be harnessed to fight the AIDS virus?
March 20, 2018 - Education and academic achievement can lessen effects of child abuse, neglect
March 20, 2018 - Researchers develop new algorithm to make CPR more effective
March 20, 2018 - Diabetes medication reduces chance of late miscarriage, premature birth among women with PCOS
March 20, 2018 - SSRIs may be more effective option for treating anxious youth, UC research shows
March 20, 2018 - Antibiotics could benefit women suffering from chronic bladder pain
March 20, 2018 - Health Highlights: March 16, 2018
March 20, 2018 - Interventional Radiology Has a Problem of ‘Unseen’ Value
March 20, 2018 - Antibodies show effectiveness for HIV prevention and promise for treatment and cure
March 20, 2018 - New 3-D-printed technology will improve radiology training
March 20, 2018 - New study identifies key role for particular gene in 16p11.2 deletion syndrome
March 20, 2018 - Red and processed meat increase the risk of liver disease
March 20, 2018 - 50% of Australians do not brush teeth twice a day
March 20, 2018 - American Gene Technologies receives second immuno-oncology patent
March 20, 2018 - Study finds no link between long-term violent video game play and adult aggression
March 20, 2018 - Weight loss surgery widely underutilized among young patients with severe obesity
March 20, 2018 - Scientists uncover new answers to cell aging in children with rare, fatal disease
March 20, 2018 - The Pistoia Alliance Calls for Greater Life Sciences Collaboration to Build the ‘Lab of the Future’
March 20, 2018 - Morning Break: Psychopathic Thought; Americans Flout Zzz’s; Farm to Pharma
March 20, 2018 - Perceptions of old age change as we age
March 20, 2018 - New standards for public involvement in research launched across the UK
March 20, 2018 - Whole Genome Sequencing used as diagnostic solution for TB
March 20, 2018 - Researchers show how two cancer genes work together to trigger leukemia
March 20, 2018 - Scientists discover basic molecular mechanism that helps understand how ALS works
March 20, 2018 - Multi-center study to evaluate promising new intervention for upper limb dysfunction after SCI
March 20, 2018 - Researchers develop technology to program DNA for delivering cancer drugs
March 20, 2018 - Northwestern scientists bring precision medicine to rheumatoid arthritis
March 20, 2018 - Research suggests possible link between heading a soccer ball and brain imbalance
March 20, 2018 - Robocall increases diabetic retinopathy screening rates among poor minorities
March 20, 2018 - INSYS Therapeutics Initiates Phase 3 Clinical Trial of Cannabidiol (CBD) Oral Solution for Treatment of Infantile Spasms
March 20, 2018 - Little Talk Between Docs and Patients Pre-PSA Screen
March 20, 2018 - Women GPs bring remote care to rural Pakistan
March 20, 2018 - Adults skipping vaccines may miss out on effective new shingles shot
March 20, 2018 - Suppressing emotions appears to reduce negative memories
March 20, 2018 - Epidural stimulation can safely, effectively normalize blood pressure in patients with SCI
March 20, 2018 - ‘Fast track’ project shows promising results in cancer whole genome analyses
March 20, 2018 - Advanced insulin pump system can also manage type 1 diabetes in children, study shows
March 20, 2018 - Flu risk less on flights if in a window seat finds study
March 20, 2018 - Sarepta Therapeutics Announces Plan to Submit a New Drug Application (NDA) for Accelerated Approval of Golodirsen (SRP-4053) in Patients with Duchenne Muscular Dystrophy (DMD) Amenable to Skipping Exon 53
March 20, 2018 - Post-Transplant Fatty Liver Disease on the Rise
March 20, 2018 - New mutation linked to ovarian cancer can be passed down through dad
March 20, 2018 - Alex’s experiences of living with rare genetic disease
March 20, 2018 - Scotland study aims to offer precise diagnoses for people with rare genetic diseases
March 20, 2018 - Stem cell treatment may help rejuvenate ovaries, avoid effects of premature menopause
March 20, 2018 - FDA Approves Hizentra (Immune Globulin Subcutaneous [Human] 20% Liquid) for the Treatment of Patients With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
March 20, 2018 - Death Strikes Young in RA
March 20, 2018 - Quiescent cells also mutate
March 20, 2018 - Stem cell-derived ocular cells treat severe AMD
March 20, 2018 - Mediterranean diet appears to be good for postmenopausal women’s bones and muscles
March 20, 2018 - Scientists discover rare childhood liver cancer’s ability to metastasize to the brain
March 20, 2018 - Treating metastatic breast cancer with immunotherapy
March 20, 2018 - The 5:2 diet could have beneficial impact on important risk markers for cardiovascular disease
March 20, 2018 - Congress tackles the opioid epidemic. But how much will it help?
March 20, 2018 - Neanderthals Just Part of the Evolutionary Puzzle
March 20, 2018 - Higher Mortality With Surgery for Early NSCLC
March 20, 2018 - Researchers go skin deep to explore what causes wrinkles
March 20, 2018 - E-cigarette use linked to fat accumulation in the liver
Skinny in 20s, Earlier Menopause Later?

Skinny in 20s, Earlier Menopause Later?

image_pdfDownload PDFimage_print

THURSDAY, Oct. 26, 2017 (HealthDay News) — Young women who are underweight may have an increased risk of early menopause, potentially jeopardizing their health, a large new study suggests.

The study found that those who were underweight in younger adulthood were 30 percent more likely to go through early menopause, compared to normal-weight women.

Early menopause — defined in this study as before age 45 — is a concern for several reasons. It shortens a woman’s reproductive life, and has been tied to heightened risks of heart disease, osteoporosis and memory decline.

The new findings don’t prove that being underweight directly causes early menopause, said lead researcher Kathleen Szegda, of Partners for a Healthier Community in Springfield, Mass.

“This is suggestive, and needs to be followed up with additional studies,” she said.

Still, there are known links between weight and a woman’s menstrual cycle, Szegda noted. Some underweight women, for example, stop getting their periods altogether, in what’s called amenorrhea — though it’s not clear if that would contribute to early menopause.

One theory, Szegda said, is that some underweight women may have been small at birth, too. That means they could have been born with a smaller “ovarian pool,” or number of eggs.

The findings, published Oct. 26 in the journal Human Reproduction, are based on nearly 79,000 U.S. nurses taking part in a large health study. They were between the ages 25 and 42 at the study’s outset, in 1989.

Over the next 22 years, just over 2,800 of those women went through early menopause. And the chances were higher among those who’d been underweight at age 18 or 35 — the two time points the researchers analyzed.

“Underweight” was defined as a body mass index (BMI) below 18.5. BMI is a measure of weight in relation to height, and figures between 18.5 and 24.9 are considered “normal.” So, the researchers explained, a woman 5 feet 5 inches tall who weighs 111 pounds or less would be considered underweight.

Most of the underweight women did not go through early menopause: For example, of roughly 1,100 women who were underweight at age 35, only 61 went through menopause early.

But their risks were higher, even compared with women at the lower end of the normal-weight range: The odds of early menopause were 56 percent higher among women who were underweight at age 35, and 51 percent higher if they were underweight at age 18.

“This is more evidence that you really can be too thin,” said Dr. Lila Nachtigall, a professor of obstetrics and gynecology at NYU Langone Medical Center in New York City.

Nachtigall, who was not involved in the study, did point to some limitations with the research.

For one, she said, some underweight women may have mistakenly said they’d gone through menopause when they were really experiencing amenorrhea.

Plus, the researchers did not know whether the women were naturally very thin or had an eating disorder.

Nachtigall said the potential role of malnutrition is important since that could contribute to “ovarian failure” and menopause.

Szegda’s team did find some evidence that extreme weight “cycling” was a culprit. The risk of early menopause was highest among underweight women who also reported major weight changes — losing at least 20 pounds three or more times in young adulthood.

But, Szegda said, that was based on a handful of women, so it’s not clear what to make of it.

Since early menopause is linked to certain diseases, it is a concern beyond fertility, Nachtigall said.

Women who do transition early, she said, should pay extra attention to their risk factors for heart disease and osteoporosis — regardless of their weight. That means being vigilant about diet and exercise, and reining in conditions such as high blood pressure and high cholesterol.

Underweight women, Nachtigall added, may need a nutritional evaluation to make sure they are getting enough protein, fat, vitamins and minerals.

SOURCES: Kathleen Szegda, Ph.D., M.P.H., director, community research and evaluation, Partners for a Healthier Community, Public Health Institute of Western Massachusetts, Springfield, Mass.; Lila Nachtigall, M.D., professor, obstetrics and gynecology, NYU Langone Medical Center, New York City; Oct. 26, 2017, Human Reproduction, online

News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services.

Tagged with:

About author

Related Articles