Breaking News
November 18, 2017 - Harris Health System RNs named among 20 Outstanding Nurses for 2017
November 18, 2017 - Old World monkeys could be key to a new, powerful rheumatoid arthritis therapy
November 18, 2017 - Mount Sinai researchers identify new therapeutic target for ER+ breast cancer
November 18, 2017 - Age, CRP levels predict success in tapering of biologics in rheumatoid arthritis patients
November 18, 2017 - New dye could be used to observe electrical activity of neurons in the brain
November 18, 2017 - New study further validates use of vaginal progesterone to decrease risk of preterm birth
November 18, 2017 - Russian researcher determined range of reference values for boron in the human body
November 18, 2017 - ‘What the Health?’ Tax bill or health bill?
November 18, 2017 - Could Your Cat Give You ‘Bird Flu?’
November 18, 2017 - Vitamin D Linked to Fertility Outcomes in ART
November 18, 2017 - Neuroscientists identify genetic changes in microglia in a mouse model of neurodegeneration and Alzheimer’s disease
November 18, 2017 - Tax reform proposal could impact care for older Americans
November 18, 2017 - PCSK9 inhibitor offers clinical benefit to patients with peripheral artery disease
November 18, 2017 - Researchers receive £1.3 million to develop sight-saving imaging technology
November 18, 2017 - Novel buckypaper sensor could pave way for high-performance, affordable wearable technology
November 18, 2017 - Despite ACA cost protections, most adolescents skip regular checkups
November 18, 2017 - Stem cell treatment allows paraplegic rats to walk and regain sensory perception
November 18, 2017 - HTC analytical conference comes to the UK
November 18, 2017 - Face It: Drinking, Smoking Takes Toll on Looks: MedlinePlus Health News
November 18, 2017 - New research shows where in the brain the earliest signs of Alzheimer’s occur
November 18, 2017 - Philips announces launch of global movement to raise awareness for COPD
November 18, 2017 - University of Bristol awarded grant to reduce antibacterial drug resistance in Thailand
November 18, 2017 - New oxytocin chemical sensor could be first step towards early diagnosis of autism
November 18, 2017 - Study finds medical cannabis is effective at reducing opioid addiction
November 18, 2017 - Specially tailored, ultrafast light pulses can trigger neurons to fire in different patterns
November 18, 2017 - Decrease in sunshine linked to rising incidence of Rickets
November 18, 2017 - Harnessing social media big data to fight against prescription drug crisis
November 18, 2017 - Researchers find way to switch tumor cells between 2D and 3D morphology
November 18, 2017 - FDA Approves Hemlibra (emicizumab-kxwh) for Hemophilia A with Inhibitors
November 18, 2017 - Adolescents underreport amphetamine use, likely unaware that adderall is amphetamine
November 18, 2017 - Study reveals a reduced risk of teenage eczema in breastfed babies
November 18, 2017 - Separating side effects could pave way for safe, effective pain medications
November 18, 2017 - Gut bacteria at young age can contribute to MS disease onset and progression, study suggests
November 18, 2017 - Environmental triggers may play role in development of Lupus
November 18, 2017 - Review looks into conventional versus new treatment modalities in orthodontic pain management
November 17, 2017 - FDA Alert: Diphenoxylate Hydrochloride and Atropine Sulfate Tablets by Greenstone: Recall
November 17, 2017 - For older women, every movement matters
November 17, 2017 - Talking-based therapy could transform aftercare for cancer survivors
November 17, 2017 - Olympus IXplore SpinSR10 imaging system enables researchers to observe fine details in live cells
November 17, 2017 - Study explores reasons for underrepresentation of minorities in genetic cancer research
November 17, 2017 - California firm running physician practices is closing down as scrutiny ramps up
November 17, 2017 - BMI not valid measure of obesity in postmenopausal women, study shows
November 17, 2017 - Vaginal progesterone decreases the risk of premature birth in women with short cervix
November 17, 2017 - Pricey ER Tests for Chest Pain Often Unnecessary
November 17, 2017 - ‘Old’ Lungs May Be Good Transplant Options: MedlinePlus Health News
November 17, 2017 - How not to gain weight over the holidays
November 17, 2017 - Researchers map first-ever proteome of healthy human heart
November 17, 2017 - Drug used to prevent and treat malaria may also be effective for Zika virus
November 17, 2017 - One in 20 children still receiving codeine to treat pain despite warning from federal regulators
November 17, 2017 - Improving clinical trials with machine learning
November 17, 2017 - Experts identify mental exercise program that can reduce risk of dementia
November 17, 2017 - Just-in-time 3-D implants set to transform tumor surgery
November 17, 2017 - Skin patch offers hope for people with peanut allergy
November 17, 2017 - Scientists identify biomarkers that predict risk of death in Ebola patients
November 17, 2017 - Heart attack, stroke patients have improved outcomes when statins are prescribed after discharge
November 17, 2017 - Majority of people do not understand link between obesity and cancer, study shows
November 17, 2017 - Deep vein thrombosis accurately diagnosed by GPs trained in compression ultrasonography
November 17, 2017 - New Kevlar-based hydrogel recreates the magic of natural cartilage
November 17, 2017 - FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence
November 17, 2017 - Foods made with biofortified corn flour and eggs retain vitamin A after cooking
November 17, 2017 - Integrated Care Winning the Day for Healthcare Companies
November 17, 2017 - CPAP may be superior to gastric banding for severe sleep apnea
November 17, 2017 - New pain relievers reduce opiate overdose risk
November 17, 2017 - Brain astrocytes could play key role in pathogenesis of Alzheimer’s disease
November 17, 2017 - Researchers test whether LVAD surgery could reverse frailty in older adults with heart failure
November 17, 2017 - ATS debuts new video to highlight dangers of flavored tobacco
November 17, 2017 - Medicaid expansion under ACA more likely to increase smoking cessation rates among low-income adults
November 17, 2017 - FDA Approves Mepsevii (vestronidase alfa) for Mucopolysaccharidosis Type VII
November 17, 2017 - 1 in 5 Americans Still Uses Tobacco, Gov’t. Reports: MedlinePlus Health News
November 17, 2017 - People with psychotic-like experiences spend less time in healthy brain states
November 17, 2017 - Hospital Readmission Reduction Program linked to increase in death rates, study finds
November 17, 2017 - Study finds rising rates of marijuana use in states where it is legal
November 17, 2017 - Scientists unveil pathology underlying optic nerve hypoplasia in children
November 17, 2017 - Novel device designed to treat diastolic heart failure found safe and effective
November 17, 2017 - Smoking parents may underestimate kid’s exposure to secondhand smoke
November 17, 2017 - FAIMS technology holds potential to be effective screening tool for pancreatic cancer
November 17, 2017 - Applying AFM to study the viscoelastic properties of cells
November 17, 2017 - FDA Alert: Nexterone (amiodarone HCl) 150 mg/100 mL Premixed Injection: Recall
November 17, 2017 - High cognitive ability not a safeguard from conspiracies, paranormal beliefs
November 17, 2017 - Computerized speed of processing training results in decreased risk of dementia
Experimental ‘golden’ potato could hold power to prevent disease in developing nations

Experimental ‘golden’ potato could hold power to prevent disease in developing nations

image_pdfDownload PDFimage_print

An experimental “golden” potato could hold the power to prevent disease and death in developing countries where residents rely heavily upon the starchy food for sustenance, new research suggests.

A serving of the yellow-orange lab-engineered potato has the potential to provide as much as 42 percent of a child’s recommended daily intake of vitamin A and 34 percent of a child’s recommended intake of vitamin E, according to a recent study co-led by researchers at The Ohio State University.

Women of reproductive age could get 15 percent of their recommended vitamin A and 17 percent of recommended vitamin E from that same 5.3 ounce (150 gram) serving, the researchers concluded.

The study appears in the journal PLOS ONE.

Potato is the fourth most widely consumed plant food by humans after rice, wheat and corn, according to the U.S. Department of Agriculture. It is a staple food in some Asian, African and South American countries where there is a high incidence of vitamin A and vitamin E deficiencies.

“More than 800,000 people depend on the potato as their main source of energy and many of these individuals are not consuming adequate amounts of these vital nutrients,” said study author Mark Failla, professor emeritus of human nutrition at Ohio State.

“These golden tubers have far more vitamin A and vitamin E than white potatoes, and that could make a significant difference in certain populations where deficiencies – and related diseases – are common,” said Failla, a member of Ohio State’s Foods for Health Discovery Theme.

Vitamin A is essential for vision, immunity, organ development, growth and reproductive health. And Vitamin A deficiency is the leading cause of preventable blindness in children. Vitamin E protects against oxidative stress and inflammation, conditions associated with damage to nerves, muscles, vision and the immune system.

In Failla’s lab, researchers created a simulated digestive system including a virtual mouth, stomach and small intestine to determine how much provitamin A and vitamin E could potentially be absorbed by someone who eats a golden potato. Provitamin A carotenoids are converted by enzymes into vitamin A that the body can use. Carotenoids are fat-soluble pigments that provide yellow, red and orange colors to fruits and vegetables. They are essential nutrients for animals and humans.

“We ground up boiled golden potato and mimicked the conditions of these digestive organs to determine how much of these fat-soluble nutrients became biologically available,” he said.

The main goal of the work was to examine provitamin A availability. The findings of the high content and availability of vitamin E in the golden potato were an unanticipated and pleasant surprise, Failla said.

The golden potato, which is not commercially available, was metabolically engineered in Italy by a team that collaborated with Failla on the study. The additional carotenoids in the tuber make it a more nutritionally dense food with the potential of improving the health of those who rely heavily upon potatoes for nourishment.

While plant scientists have had some success cross-breeding other plants for nutritional gain, the improved nutritional quality of the golden potato is only possible using metabolic engineering – the manipulation of plant genes in the lab, Failla said.

While some object to this kind of work, the research team stresses that this potato could eventually help prevent childhood blindness and illnesses and even death of infants, children and mothers in developing nations.

“We have to keep an open mind, remembering that nutritional requirements differ in different countries and that our final goal is to provide safe, nutritious food to 9 billion people worldwide,” said study co-author Giovanni Giuliano of the Italian National Agency for New Technologies, Energy and Sustainable Development at the Casaccia Research Center in Rome.

Failla said “hidden hunger” – deficiencies in micronutrients – has been a problem for decades in many developing countries because staple food crops were bred for high yield and pest resistance rather than nutritional quality.

“This golden potato would be a way to provide a much more nutritious food that people are eating many times a week, or even several times a day,” he said.

Source:

https://news.osu.edu/news/2017/11/08/research-golden-potato/

Tagged with:

About author

Related Articles