Breaking News
August 17, 2018 - UCR receives 2018 Inspiring Programs in STEM Award from INSIGHT Into Diversity magazine
August 17, 2018 - Researchers publish new paper on developing vaccine candidates for Helminthic parasites
August 17, 2018 - Researchers develop new method to diagnose broad range of cancers using malaria protein
August 17, 2018 - Female mosquitoes quickly evolve selective mating behavior when faced with threats
August 17, 2018 - FDA Grants Breakthrough Therapy Designation to Daiichi Sankyo’s FLT3 Inhibitor Quizartinib for Relapsed/Refractory FLT3-ITD AML
August 17, 2018 - Resistance training and exercise motivation go hand-in-hand
August 17, 2018 - A lesson for future doctors: Listen to and learn from your patients
August 17, 2018 - NUS study discovers a bidirectional regulator and shines light on A-to-I RNA editing in cancer cells
August 17, 2018 - Research shows link between high blood levels of omega-3s and better brain function in children
August 17, 2018 - Researchers propose new theory for how rare gene mutations cause Alzheimer’s disease
August 17, 2018 - Digital psychiatric therapy can ‘rewire’ the brain in children with ADHD, study shows
August 17, 2018 - Psychologist to assess how the brain maintains precise short-term and long-term memories
August 17, 2018 - Eating white button mushrooms could improve regulation of glucose in the liver
August 17, 2018 - Scientists identify mutational signatures in ovarian cancer
August 17, 2018 - Sun Pharma receives U.S. FDA approval for CEQUA to treat patients with dry eye disease
August 17, 2018 - Teva Announces Updated Indication and Vial Presentation for Granix (tbo-filgrastim) Injection in United States
August 17, 2018 - Study shows DNA methylation related to liver disease among obese patients
August 17, 2018 - Life on the border: Back at Stanford, ready to pitch in
August 17, 2018 - New device for accurately placing hemodialysis catheters on kidney patients
August 17, 2018 - New strategy accelerates, automates process of prototype molecule optimization
August 17, 2018 - Study finds role of autoimmunity in development of COPD
August 17, 2018 - Researchers transform research tool to study neuronal function
August 17, 2018 - Cognitive impairment does not equate to unhappiness in older adults
August 17, 2018 - Peer Comparisons Can Decrease Risky Prescribing Patterns
August 17, 2018 - Susceptible genes identified for childhood chronic kidney disease
August 17, 2018 - Research uncovers miscarriage cause, identifies potential targets for treatment
August 17, 2018 - Bacterial armor could be new target for antibiotics | News Center
August 17, 2018 - FDA expands approval of Vertex’ cystic fibrosis medicine to treat children aged 12 to
August 17, 2018 - Give Your Child a Head Start With Math
August 17, 2018 - Ground-breaking study tests whether rejected livers can be made viable for transplantation
August 16, 2018 - New algorithm could improve diagnosis of rare diseases | News Center
August 16, 2018 - SCHILLER introduces latest generation of ECG device, CARDIOVIT AT-102 G2
August 16, 2018 - Proper treatment, refraining from smoking can reduce heart disease risk from type 2 diabetes
August 16, 2018 - Mount Sinai study could transform treatment for patients with retinal degenerative diseases
August 16, 2018 - Penn researchers develop first mouse model of idiopathic pulmonary fibrosis
August 16, 2018 - Four tips to help prevent fall allergy symptoms
August 16, 2018 - Women’s Preventive Services Initiative says screen all women annually for urinary incontinence
August 16, 2018 - At Stanford, patient discovers the source of her headaches, nausea | News Center
August 16, 2018 - To Prevent Injuries in Young Baseball Players, Chris Ahmad Reaches Out to Parents
August 16, 2018 - Restoring blood flow may be linked to longer survival in patients with critical limb ischemia
August 16, 2018 - New model of genetically engineered immune cells may help fight solid tumors
August 16, 2018 - Maternal stress increases anxious and depressive-like behaviors in female offspring
August 16, 2018 - Childhood exposure to secondhand smoke increases risk of COPD death in adulthood
August 16, 2018 - Scientists uncover key control mechanism of DNA replication
August 16, 2018 - NIH begins first-in-human trial of experimental live, attenuated Zika virus vaccine
August 16, 2018 - Two diabetes medications don’t slow progression of type 2 diabetes in youth
August 16, 2018 - 5 Questions: How Stanford research is making MRI scans safer for kids | News Center
August 16, 2018 - Columbia Celebrates 25th Anniversary of White Coat Ceremony
August 16, 2018 - Phonak’s new smallest and most discreet Virto B-Titanium hearing aid
August 16, 2018 - New project aims to study growth of water-based microorganisms
August 16, 2018 - Immune cell found to play important role in photosensitivity
August 16, 2018 - Higher social dominance linked to faster decision-making in men
August 16, 2018 - Blood test in early pregnancy could determine a woman’s later risk for gestational diabetes
August 16, 2018 - New research confirms link between DDT exposure and autism
August 16, 2018 - Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID’d
August 16, 2018 - Risk of heart failure up in ALVSD patients with diabetes
August 16, 2018 - Exercise reduces symptoms and fatigue in patients with chronic kidney disease
August 16, 2018 - Study reveals role of RUNX proteins in DNA repair
August 16, 2018 - New research finds no harm from average salt consumption
August 16, 2018 - Researchers develop new way of testing bacterial resistance to antibiotics
August 16, 2018 - Magnetic gene in aquarium fish could open doors to treatment for epilepsy, Parkinson’s
August 16, 2018 - Five tips for successful long-term breastfeeding
August 16, 2018 - Researchers identify brain networks involved in object naming
August 16, 2018 - Promoting HPV Vaccine Doesn’t Prompt Risky Sex by Teens: Study
August 16, 2018 - Treating Rheumatoid Arthritis: Search for a Cure
August 16, 2018 - Research shows in the long run, charcoal toothpaste likely won’t whiten teeth
August 16, 2018 - Seattle Children’s opens new clinic to provide convenient access to pediatric specialty care services
August 16, 2018 - Curious case of the lost contact lens
August 16, 2018 - GN Hearing unveils world’s first Premium-Plus hearing aid
August 16, 2018 - Parental life span linked with increased longevity and health in daughters
August 16, 2018 - Health leaders reveal ten most important medicines in NHS history
August 16, 2018 - Mobile health devices diagnose hidden heart condition in at-risk populations
August 16, 2018 - When it comes to shedding pounds, it pays to think big
August 16, 2018 - Liva Healthcare announces appointment of Thomas Cooke as clinical services manager in the UK
August 16, 2018 - New digital pharmacy aims to help people living with chronic care conditions
August 16, 2018 - Preventing ACL injuries in high school athletes
August 16, 2018 - Experts provide insight into novel concepts and approaches for stroke rehabilitation
August 16, 2018 - Scientists reverse congenital blindness in mouse model
August 16, 2018 - Study shows link between use of benzodiazepines and increased risk of Alzheimer’s disease
August 16, 2018 - Study provides new insight into how ‘trash bag of the cell’ traps and seals off waste
IUD May Lower Cervical Cancer Risk: MedlinePlus Health News

IUD May Lower Cervical Cancer Risk: MedlinePlus Health News

image_pdfDownload PDFimage_print

HealthDay news image

TUESDAY, Nov. 7, 2017 (HealthDay News) — IUD contraceptive devices may reduce a woman’s risk of cervical cancer by about a third, a new review concludes.

Researchers think IUDs might promote an immune response that kills off human papillomavirus (HPV), the virus that causes virtually all cases of cervical cancer.

“The data say the presence of the IUD in the uterus stimulates an immune response, and that immune response very, very substantially destroys sperm and keeps sperm from reaching the egg,” explained lead researcher Victoria Cortessis. “It stands to reason the IUD might influence other immune phenomenon.”

These results could be potentially lifesaving for young adult women who are too old to benefit from the HPV vaccine, said Cortessis. She is an associate professor of clinical preventive medicine at the University of Southern California’s Keck School of Medicine.

“The vaccines don’t work unless the woman is vaccinated before she’s ever exposed to the virus,” Cortessis said. “That’s why we want 11- and 12-year-olds to be vaccinated, so they have time to be fully vaccinated and have a robust immune response before” first exposure.

Unfortunately, HPV is so widespread that many contract the virus as soon as they initiate sexual activity, Cortessis continued.

“Women in their 20s and 30s and 40s who haven’t been vaccinated are not going to be protected,” Cortessis said. “That means for decades to come this epidemic of cervical cancer is with us.”

However, the study only showed an association between IUDs and a lower risk of cervical cancer. And more research is needed before gynecologists can begin recommending IUDs for protection against cervical cancer, Cortessis and other medical experts agreed.

“It raises the need for further research to be done to see if that is in fact the case,” said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society.

The intrauterine device (IUD) is a small T-shaped object placed inside the uterus to prevent pregnancy. It comes in two types — one is made of copper, while the other is plastic and emits a small amount of the female hormone progestin.

Cortessis and her colleagues suspected that the IUD might influence risk of cervical cancer because it prevents pregnancy through manipulation of the female immune system.

To explore the theory, the team scoured medical literature for research that measured IUD use and cases of cervical cancer.

The investigators found 16 high-quality studies that could be combined to provide an expanded picture of the risk of cervical cancer for women using an IUD. The data included nearly 5,000 women who developed cervical cancer and just over 7,500 women who did not.

The analysis is “fascinating,” and the potential explanation for why an IUD might reduce cervical cancer risk “really does make sense,” said women’s health specialist Dr. Jill Rabin.

“This is just one more reason potentially to help us recommend a great contraceptive method to women,” said Rabin, co-chief of the division of ambulatory care with Women’s Health Programs-PCAP Services at Northwell Health in New Hyde Park, N.Y.

But Lichtenfeld was concerned that some of the larger studies included in the analysis dated back to the 1980s and 1990s, when IUDs were being prescribed in the United States to a more select group of women.

Back then, IUDs were not recommended for use in women with two major risk factors for cervical cancer — multiple sexual partners and a history of sexually transmitted infections, Lichtenfeld explained.

“That becomes a significant factor to consider in evaluating results of this type of study,” Lichtenfeld said. “We need more contemporary data and more contemporary study to really answer the question, given those considerations.”

But Cortessis said her team took into account individual cervical cancer risk factors such as prior pregnancy, HPV status and number of sexual partners, and found that each of these factors did not affect their bottom-line findings.

Finally, Lichtenfeld said he’s concerned that people might use these results as an excuse to forgo regular Pap testing or not get their children vaccinated against HPV.

“That’s the risk of folks becoming complacent when they see this type of study,” Lichtenfeld said.

The report was published online Nov. 7 in the journal Obstetrics & Gynecology.

SOURCES: Victoria Cortessis, Ph.D., associate professor, clinical preventive medicine, University of Southern California’s Keck School of Medicine; Jill Rabin, M.D., co-chief, division of ambulatory care, Women’s Health Programs-PCAP Services, Northwell Health, New Hyde Park, N.Y.; Len Lichtenfeld, M.D., deputy chief medical officer, American Cancer Society; Nov. 7, 2017, Obstetrics & Gynecology, online

News stories are written and provided by HealthDay and do not reflect federal policy, the views of MedlinePlus, the National Library of Medicine, the National Institutes of Health, or the U.S. Department of Health and Human Services.

Tagged with:

About author

Related Articles