Breaking News
August 14, 2018 - Reducing opioid prescriptions for one operation can also spill over to other procedures
August 14, 2018 - E-cigarettes not so safe but still better than cigarettes
August 14, 2018 - Researchers find link between common ‘harmless’ virus and cardiovascular damage
August 14, 2018 - Initiation of PIMs associated with higher risk of fracture-specific hospitalizations and mortality
August 14, 2018 - Genetically modified mosquitoes and special bed nets help tackle deadly diseases
August 14, 2018 - Advances in treating hep C lead to new option for transplant patients
August 14, 2018 - Study finds quality of doctor-patient discussions about lung cancer screening to be ‘poor’
August 14, 2018 - MSU researchers uncover the effects of aging on regenerative ability of kidneys
August 14, 2018 - Better conditioning, throwing mechanics can help reduce elbow injuries in young baseball pitchers
August 14, 2018 - Brain game doesn’t offer brain gain
August 14, 2018 - Reproductive choices facing women with disabilities require careful consideration
August 14, 2018 - Scientists pinpoint the cause of a rare childhood seizure disorder
August 14, 2018 - Lumpectomy plus radiation associated with reduced risk of breast cancer death, study finds
August 14, 2018 - UAB study shows how ion channel differentiates newborn and mature neurons in the brain
August 14, 2018 - Experts highlight key knowledge gaps that need to be addressed in Ebola vaccine research
August 14, 2018 - Discovery could lead to new drugs against infection and inflammation
August 14, 2018 - Infection Prevention Differs Between Small, Large Hospitals
August 14, 2018 - Mom still matters—In study, young adults tended to prioritize parents over friends
August 14, 2018 - Deep brain stimulation might benefit those with severe alcoholism, preliminary studies show
August 14, 2018 - Study finds increased rate of repeat pregnancies in women with intellectual and developmental disabilities
August 14, 2018 - Lighter sedation fails to reduce risk of postoperative delirium in older patients
August 13, 2018 - Asking better questions about person’s memory could improve doctors’ understanding of patients
August 13, 2018 - U.S. Trauma Doctors Push for Stricter Gun Controls
August 13, 2018 - Asthma and flu: a double whammy
August 13, 2018 - 5 Questions: Donna Zulman on engaging high-need patients in intensive outpatient programs | News Center
August 13, 2018 - Behavioral Nudges Lead to Drop in Prescriptions of Potent Antipsychotic
August 13, 2018 - Potential New Class of Drugs May Reduce Cardiovascular Risk by Targeting Gut Microbes
August 13, 2018 - How to get your kids to eat better
August 13, 2018 - The importance of hearing your patients
August 13, 2018 - Transmission of F. tularensis unlikely to happen through the food chain
August 13, 2018 - Researchers discover epigenetic mechanism underlying ischemic cardiomyopathy
August 13, 2018 - Adolescent health programs receive only a tiny share of international aid, finds research
August 13, 2018 - Fracture risk increases by 30% after gastric bypass, study shows
August 13, 2018 - Quality-improvement project to standardize feeding practices helps micro preemies gain weight
August 13, 2018 - Long-term cannabinoid exposure impairs memory, study shows
August 13, 2018 - New intervention to reduce risk of HIV in young transgender women
August 13, 2018 - Japan human trial tests iPS cell treatment for Parkinson’s
August 13, 2018 - Altered nitrogen metabolism may contribute to emergence of new cancer mutations
August 13, 2018 - Cycling provides greatest health benefits, study finds
August 13, 2018 - Scientists discover biomarker for kidney cancer
August 13, 2018 - New test predicts the risk of serious disease before symptoms appear
August 13, 2018 - Cianna Medical receives FDA 510(k) clearance to extend indication of SCOUT reflector for use in soft tissue localization
August 13, 2018 - Ground-breaking discovery offers new hope for treatment of Alzheimer’s, other neurological diseases
August 13, 2018 - Medical nutrition therapy provided by RDNs benefits patients with chronic kidney disease
August 13, 2018 - Prenatal Tdap vaccination not linked with increased risk of autism in children, study shows
August 13, 2018 - One-Third of Canadian Patients Get Hip Fx Repair Within 24 Hours
August 13, 2018 - ANA (Antinuclear Antibody) Test: MedlinePlus Lab Test Information
August 13, 2018 - Traffic jams in the brain
August 13, 2018 - NIH awards $6.5 million to establish multi-institution biomedical technology resource center
August 13, 2018 - New marker in the blood could help predict person’s risk of developing kidney cancer
August 13, 2018 - New biomarker may provide clues to create diagnostic tool for hypoglycemia-associated autonomic failure
August 13, 2018 - Oxidative Stress Hampers Blood Vessel Dilation in Men
August 13, 2018 - Parents’ Religious Beliefs May Affect Kids’ Suicide Risk: Study
August 13, 2018 - Measure of belly fat in older adults is linked with cognitive impairment
August 13, 2018 - FDA permits marketing of first mobile medical app for contraceptive use to prevent pregnancy
August 13, 2018 - NUS scientists develop new technology to customize optimal drug ‘cocktail’ for myeloma patients
August 13, 2018 - Disordered eating behaviors up for overweight young adults
August 13, 2018 - Connection between Alzheimer’s disease and degenerative eye diseases
August 13, 2018 - Employer expectation of checking email during nonwork hours affects health of workers and families
August 13, 2018 - Rotavirus vaccination reduces infant diarrhea deaths by 34% in rural Malawi
August 13, 2018 - Approval of drug derived from cannabis not necessarily a win for weed
August 13, 2018 - Study shows COPD risk in women with asthma can be reduced
August 13, 2018 - FIND and genedrive announce study agreement to evaluate HCV ID Kit
August 13, 2018 - One in two people putting their eye health at risk during summer, says eye research charity
August 13, 2018 - FDA Approves Galafold (migalastat) for the Treatment of Fabry Disease
August 13, 2018 - Is too much screen time harming children’s vision?
August 13, 2018 - GNA Biosolutions named as winner of AACC Disruptive Technology Award
August 13, 2018 - New ‘closed-loop’ brain stimulation method improves learning, memory, and skill acquisition
August 13, 2018 - FOXM1 contributes to treatment failure in acute myeloid leukemia
August 13, 2018 - Autoimmune response drives neurodegeneration in glaucoma
August 12, 2018 - Preschooler’s Perfectionism May Predict OCD in Adolescence
August 12, 2018 - Dry mouth problems may be associated with disease in the eyelids
August 12, 2018 - Proof-of-concept technology using nanoparticles could offer new approach for oral medications
August 12, 2018 - GSS sensors provide stable CO2 control for laboratory incubator applications
August 12, 2018 - For Seniors, Getting Physical Protects the Heart
August 12, 2018 - Updated Blood Pressure Guidelines: Lifestyle Changes are Key
August 12, 2018 - Review finds more effective drugs to stop bleeding after childbirth
August 12, 2018 - Study provides snapshot of mechanism behind cancer metastasis for the first time
August 12, 2018 - Birth study empowers pregnant women
August 12, 2018 - New drug makes rats to self-administer alcohol less frequently
Comprehensive review finds increasing number of new heart failure cases in the UK

Comprehensive review finds increasing number of new heart failure cases in the UK

image_pdfDownload PDFimage_print

Between 2002 and 2014, the number of new cases of heart failure in the UK increased by 12% – from 170727 to 190798 cases, according to the most comprehensive review of heart failure statistics in the UK, published in The Lancet. The number of new heart failure cases in 2014 was similar to the combined number of new cases of breast, prostate, lung and bowel cancer (189136 cases in 2014).

The increasing number of new heart failure cases comes as a result of population ageing and growth, while the corresponding incidence rates decreased by 7% between 2002 and 2014 (from 358 cases per 100000 people, to 332 per 100000).

Similarly, prevalence rates have remained stable over this period, but the number of existing chronic heart failure cases has increased substantially (by 23% – from 750127 to 920616 cases), which is likely to be a result of people living longer after heart failure.

Heart failure means the heart is less able to pump blood around the body. This occurs after the heart becomes damaged, typically as a result of a heart attack, high blood pressure or cardiomyopathy.

The results illustrate the successes of prevention measures, such as public health measures to reduce common cardiovascular risk factors (such as smoking cessation or improved diet), and improvements in clinical care (such as better management of heart attacks, hypertension or diabetes), but also demonstrate the vast impending burden for healthcare resources in the UK.

“Our findings have important implications for healthcare resource planning and prevention strategies, as the number of people affected by heart failure grows and places an ever-greater burden on health services,” says Professor Kazem Rahimi, The George Institute for Global Health, the University of Oxford, UK. “To counter this, we need stronger public health action in disease prevention, improved resource planning, and efficient and effective care for newly-diagnosed patients and those surviving heart failure.”

The study is the largest investigation of heart failure incidence to link data from primary and secondary care to capture the full burden of heart disease, and distinguish between new and existing cases of heart failure. It reviews the medical records of more than 3.9 million patients between January 2002 and December 2014, including people newly diagnosed and people living with heart failure during that period.

The researchers looked at patients’ medical and social factors, such as blood pressure, BMI, whether they smoked, and any other chronic conditions they had, as well as socioeconomic status, ethnicity and where they lived.

The results highlight important changes in the types of people facing heart failure over time. For example, the average age of people facing heart failure has increased from 76.5 to 77 years old, and the rate of new cases in the very elderly (people aged over 85 years) increased (by 8%, from 3926 cases per 100000 people in 2002, to 4244 per 100000 in 2014). Comparatively, the proportion of new cases decreased across most other age groups – except in people aged under 55 years, where the rates were too low to be able to compare how they changed over time. The authors explain that this could be a result of it being more difficult to manage symptoms in very elderly people.

There was also a substantial increase in the number of other chronic conditions patients had, indicating that treatment of heart failure is becoming more complex, further increasing burden on health services.

Overall, the number of other chronic conditions increased from an average of 3.4 conditions in 2002, to 5.4 in 2014, with an increasing number of people having three or more other conditions (68% of patients in 2002, compared with 87% in 2014). The authors note that this increase in other conditions may be due to several factors, such as population ageing, more disease screening programmes, greater awareness from doctors, and changes in types of risk factor.

The study quantifies the magnitude of socioeconomic inequalities in heart failure – with people from the most deprived backgrounds being 61% more likely to experience heart failure than people from the most affluent backgrounds – and also illustrates stark differences in people’s age at diagnosis and levels of other chronic conditions.

Overall, people from the most deprived backgrounds were around 3.5 years younger when they had heart failure than the most affluent (74.5 years old vs 77.8 years, respectively). This gap in age also widened between 2002-2014, with average age at diagnosis reducing by almost half a year in the most deprived, while it increased by approximately 2.5 years in the most affluent groups.

In addition, the proportion of patients presenting with three or more other chronic conditions ranged from 81% for the most deprived, to 77% for the least deprived group.

The authors calculate that if these inequities could be removed, there would be 31810 fewer heart failure cases annually in the UK.

“The disparities we have identified in the UK point to a potentially preventable nature of heart failure that still needs to be tackled, and to potential opportunities for more targeted and equitable prevention strategies,” says Professor Rahimi. “Achieving equal access and use of healthcare is an important goal, and in this instance could help to tackle the biological, environmental and behavioral risk factors that put people from more deprived background at greater risk of heart failure.”

With many other populations ageing, the authors say that their findings could be applicable to many other developed countries.

They also note some limitations, including that some of the findings coincide with the introduction of a national care monitoring program (the Quality and Outcomes Framework which was introduced between 2004-2006, while this study ran from 2002-2014) and this may explain some of the variation observed in these years.

The data used did not specify the type of heart failure patients faced, and the study relied on the accuracy of people’s medical records.

Writing in a linked Comment, Dr Faiez Zannad, Université de Lorraine, France, says:

Estimates of heart failure incidence and prevalence are difficult to generate. Accurate epidemiological estimates of heart failure, however, are crucial to ensure resources are appropriately and adequately allocated to treat patients with existing disease, and to inform prevention methods among those at risk… Despite their similar epidemiology, and worse survival for patients with heart failure compared with many forms of cancer, there is a continued disparity between the diseases in terms of research investment, focused prevention, and societal awareness. Perhaps these data will stimulate change and encourage heart failure to be addressed as an equal priority with cancer.

Source:

http://www.thelancet.com/

Tagged with:

About author

Related Articles