Breaking News
December 12, 2017 - CAR T cell therapy shows long-lasting remissions in non-Hodgkin’s lymphoma patients
December 12, 2017 - Live-cell microscopy reveals internal forces that direct cell migration
December 12, 2017 - GSK Submits US Regulatory Application for Single-Dose Tafenoquine for Plasmodium vivax Malaria
December 12, 2017 - High Blood Urea Nitrogen Levels Tied to T2D Risk
December 12, 2017 - Blood Smear: MedlinePlus Lab Test Information
December 12, 2017 - Atopic eczema—one size does not fit all
December 12, 2017 - Biological Applications of AFM
December 12, 2017 - Study provides new insights into mechanism of tumor survival in glioblastoma
December 12, 2017 - FDA Approves Admelog (insulin lispro) Short-Acting “Follow-On” Insulin Product to Treat Diabetes
December 12, 2017 - Chromosomes Fact Sheet – National Human Genome Research Institute (NHGRI)
December 12, 2017 - Discovery puts the brakes on HIV’s ability to infect
December 12, 2017 - Researchers uncover novel strategy to program immune system for fighting cancer
December 12, 2017 - Study finds under-age marriage for women as marker of multiple vulnerabilities
December 12, 2017 - Scientists discover specific mechanism of Zika virus-associated microcephaly
December 12, 2017 - Creating Your Family Health Tree
December 12, 2017 - Biological Pathways Fact Sheet – National Human Genome Research Institute (NHGRI)
December 12, 2017 - LSUHealthNO breakthrough may pave way for advances in obesity-related diseases
December 12, 2017 - Few people with HIV get prompt care after incarceration
December 11, 2017 - Air pollution exposure before or after conception linked to increased risk of birth defects in children
December 11, 2017 - Abu Dhabi focuses on reducing childhood obesity
December 11, 2017 - Employees with influenza have more lost work time
December 11, 2017 - type 2 diabetes – Genetics Home Reference
December 11, 2017 - Insufficient evidence to guide recommendations on vitamin D in pregnancy
December 11, 2017 - St. Jude gene therapy offers hope for infants with ‘bubble boy’ disease
December 11, 2017 - Soy foods, cruciferous vegetables may reduce breast cancer treatment’s side effects
December 11, 2017 - Nearly 3 in 10 elite footballers at top clubs have undetected lung and airway problems, study finds
December 11, 2017 - Why some workers can’t call it quits
December 11, 2017 - Healthier Diet, Less Salt: The Recipe to Beat High Blood Pressure: MedlinePlus Health News
December 11, 2017 - Research leads to call for lung health screening at top football clubs
December 11, 2017 - Drug improves disease-free, overall survival after hematopoietic stem cell transplants
December 11, 2017 - Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer
December 11, 2017 - New, more easily administered therapies offer benefits for bleeding and clotting disorders
December 11, 2017 - Opioids after surgery left her addicted. Is that a medical error?
December 11, 2017 - Scientists develop software that predicts leukemia-specific immune targets
December 11, 2017 - Does Your Pet Have a Weight Problem? Here’s How to Tell: MedlinePlus Health News
December 11, 2017 - Genetic variant prompts cells to store fat, fueling obesity
December 11, 2017 - Canola oil linked to worsening of Alzheimer’s
December 11, 2017 - New Breast Cancer Drug Ribociclib (Kisqali) May Benefit Younger Women, Too
December 11, 2017 - Healthy Living May Ease Some MS Symptoms: MedlinePlus Health News
December 11, 2017 - Researchers develop a molecular taxonomy for hair disorders
December 11, 2017 - Study shows safety, efficacy of cystic fibrosis drug in children between 1 to 2 years of age
December 11, 2017 - Two immunotherapy approaches for multiple myeloma show hope
December 11, 2017 - The Valley Hospital uses novel mobile app to enhance pre-hospital emergency care
December 11, 2017 - ‘I Entered Medical School Through a Hunger Strike’: What We Heard This Week
December 11, 2017 - Research team unlocks secrets of Ebola
December 11, 2017 - Generic versions of Viagra coming this week
December 11, 2017 - New genetic model identified for predicting outcomes in patients with primary myelofibrosis
December 11, 2017 - Research shows that e-cigarettes serve as gateway to traditional smoking
December 11, 2017 - A risk factor for drug-induced skin disease identified
December 11, 2017 - MIT researchers discover new way to make bacteria vulnerable to existing antibiotics
December 11, 2017 - Dengue vaccine issues in the Philippines
December 11, 2017 - Office Workers Don’t Like Being Chained to Their Desks: MedlinePlus Health News
December 11, 2017 - Study reveals how a very low calorie diet can reverse type 2 diabetes
December 11, 2017 - Study highlights potential for reducing greenhouse gas emissions in health care settings
December 11, 2017 - University of Adelaide receives $23.2 million for preterm birth research
December 11, 2017 - Tough Flu Season Ahead: Vaccine May Only Be 10% Effective
December 11, 2017 - Getting Self-Driving Cars on the Road Soon Might Save Lives: MedlinePlus Health News
December 11, 2017 - Enterovirus vaccine prevents virus-induced diabetes in a T1D experimental model
December 11, 2017 - Solar retinopathy or sun damage to the eyes – a case report
December 11, 2017 - Cancer risk with birth control pills emerges again in latest study
December 10, 2017 - Deer Hunters: Put Safety First: MedlinePlus Health News
December 10, 2017 - High blood pressure is redefined as 130, not 140: US guidelines (Update)
December 10, 2017 - Unusual neuroinflammation may underlie cognitive problems in cART-treated HIV patients
December 10, 2017 - Racial differences in parents’ reports of child’s autism symptoms may contribute to delayed diagnosis
December 10, 2017 - Taurine could boost effectiveness of existing multiple sclerosis therapies
December 10, 2017 - The man with a young woman’s heart
December 10, 2017 - Patient bedside remains important component of medical education for students
December 10, 2017 - Nutrition labeling has little impact on sodium consumption
December 10, 2017 - ‘Obesity paradox’ not present among people with new cases of cardiovascular disease
December 10, 2017 - SLU scientists provide promising approach in designing new drugs for DMD
December 10, 2017 - Can PD-1 Inhibitor Help Eradicate HIV?
December 10, 2017 - Checking Prices for Medical Procedures Online? Good Luck: MedlinePlus Health News
December 10, 2017 - Researchers find bacteria tied to esophageal cancer
December 10, 2017 - Boy’s Double Hand Transplant Changed His Brain
December 10, 2017 - Memo to Doctors: Spit Out the Bad News: MedlinePlus Health News
December 10, 2017 - Two years of extended anastrozole therapy proved as effective as five years in clinical trial
December 10, 2017 - Using digital devices before bed may contribute to sleep and nutrition problems in children
December 10, 2017 - Are You Sure That’s What the Doctor Said About Your Leukemia?: MedlinePlus Health News
December 10, 2017 - Low vitamin D levels at birth linked to higher autism risk
December 10, 2017 - Alcohol use in movies influences onset of drinking among 10- to 15-year-olds
Disparities in exposure to toxins may drive higher diabetes rates in minorities

Disparities in exposure to toxins may drive higher diabetes rates in minorities

image_pdfDownload PDFimage_print

Unequal exposure to environmental pollutants acting as endocrine-disrupting chemicals is an under-recognized risk factor that may play a key role in driving the higher rates of diabetes among minority and low-income populations, according to a new article in the journal Diabetes Care.

Endocrine-disrupting chemicals interfere with the body’s ability to produce or respond to hormones. Many of these chemicals can hinder the production or use of insulin—a hormone produced by the pancreas that allows the body to use sugar from food for fuel. An inability to produce or properly use insulin causes diabetes, which affects approximately 24 million Americans.

Compared to whites, the risk for developing diabetes is estimated to be 66 percent higher for Latinos and 77 percent higher for blacks. Approximately 18 percent of blacks and 20 percent of Latinos have diabetes, compared with 9 percent of whites.

While studies have examined disparities in exposure to endocrine-disrupting chemicals across diverse populations—and implicated these same chemicals in helping to promote the development of diabetes—none have made the connection that overexposure to these chemicals among minority and low-income populations may contribute to their increased burden of diabetes.

“The burden of diabetes isn’t borne uniformly by society,” said Dr. Robert Sargis, assistant professor of endocrinology, diabetes and metabolism in the UIC College of Medicine and one of the lead authors on the paper. “In order to address this disparity, we need to know all the contributing factors.”

Black, Latino and low-income populations historically have carried the heaviest burden of diabetes. Studies are now looking at the role of disproportionate environmental exposures in diabetes among these groups, said Daniel Ruiz, a graduate student at the University of Chicago and a co-lead author on the paper.

Minority and low-income populations are much more likely to live in neighborhoods with a manufacturing plant, or near major sources of air pollution like highways or agricultural fields, Sargis said. “Many social and cultural factors have combined to contribute to the fact that these groups have traditionally lived in degraded areas where toxic exposures are more likely to occur,” he said.

Sargis and colleagues searched the medical literature from 1966 through 2016 for papers documenting associations between endocrine-disrupting chemicals and diabetes, and papers that reported on racial, ethnic, and/or socioeconomic disparities in exposures to endocrine-disrupting chemicals known to contribute to metabolic diseases, including diabetes.

They identified 36 studies that looked at five types of endocrine-disrupting chemicals (polychlorinated biphenyls, or PCBs; organochloride pesticides; chemicals in air pollution related to traffic; bisphenol A, or BPA; and phthalates) and diabetes risk, and 33 that had data on disparities in exposure to these chemicals.

“The majority of the studies we reviewed on exposures to endocrine-disrupting chemicals reported that low-income people of color were disproportionately exposed,” said Ruiz.

“We need to change how we think about what is driving these disparities to include the contribution of environmental pollution,” Sargis said. “Knowing that these risk factors exist presents an opportunity to mitigate them and focus on policies that reduce the risk.”

The researchers also looked at interventional studies that focused on lowering levels of endocrine-disrupting chemicals in humans. Based on these studies, they created a list of sources for each of the five chemicals they studied—along with specific exposure reduction strategies for each—with the goal of sharing it with healthcare workers.

“Health care providers need to not only become more aware of the impact of environmental exposures on their patients’ health, they should also have the resources to help their patients reduce their exposures through patient education,” said Sargis.


Explore further:
Development of screening tests for endocrine-disrupting chemicals

Journal reference:
Diabetes Care

Provided by:
University of Illinois at Chicago

Tagged with:

About author

Related Articles