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January 23, 2019 - Compound identified that may help treat heart failure
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Telestroke Doubled tPA; Humidity Risk; Epilepsy Drug for Stroke Prevention?

Telestroke Doubled tPA; Humidity Risk; Epilepsy Drug for Stroke Prevention?

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Kaiser Permanente Northern California nearly doubled thrombolytic use and cut door-to-needle times without more adverse events by implementing a standardized protocol with all emergency stroke cases managed by a dedicated telestroke neurologist. (Stroke)

The antiepileptic drug sodium valproate was associated with a 56% reduced risk of recurrent stroke after controlling for potential confounders across three prospective studies in patients with previous stroke or transient ischemic attack. (Stroke)

While perhaps not surprising, Chinese researchers offered evidence that humidity appeared to boost the cardiovascular risk of high temperatures. (International Journal of Environment Research and Public Health)

The Nanostim leadless pacemaker will stay in time-out, MassDevice reports. Abbott halted implantation more than a year ago and continues working to fix issues with the retrieval catheter docking button.

Robotic endovascular interventions are lacking — particularly in regard to 3D navigation, ergonomics, and integrated force feedback — according to the U.K. National Institute for Health Research and Imperial College London. (Digitalhealth)

A novel subcutaneous agent, RA-101495, for paroxysmal nocturnal hemoglobinuria improved lactate dehydrogenase levels and eliminated transfusion dependence in half of patients naïve to eculizumab (Soliris) infusion in the small trial. However, about two-thirds of the transfusion-dependent patients on eculizumab didn’t tolerate a switch to RA-101495. (Seeking Alpha)

Public Citizen petitioned the FDA to ban cancer drug component cesium chloride from use in compounding pharmacies due to its risk of fatal abnormal heart rhythms, cardiac arrest, and adverse neurological effects.

The Cheatham Platinum balloon-expandable stent for treating aortic coarctation got expanded clearance to patch blood vessel tears in congenital heart defect patients, the FDA announced.

A gene activity blood test helped predict survival in advanced heart failure patients getting mechanical circulatory support devices, according to a small study. (PLOS ONE)

RT-100 AC6 gene transfer therapy for heart failure with reduced ejection fraction got fast track status from the FDA. (MD Magazine)

Cardiac stem cell muscle patches implanted in pigs after an induced heart attack improved left ventricular function and wall stress, researchers reported in Circulation.

2017-12-18T13:02:42-0500

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