Breaking News
June 20, 2018 - Elevated NT-proBNP Found to Up Cardiovascular Risk in T2DM
June 20, 2018 - Genetics Home Reference: White-Sutton syndrome
June 20, 2018 - Canadian team reports success in transplanting hepatitis C organs
June 20, 2018 - Separating migrant children from parents at US border tantamount to child abuse
June 20, 2018 - Study finds more information about how gene linked to ASD affects the brain
June 20, 2018 - Floppy eyelids linked to sleep apnea
June 20, 2018 - Can-Fite provides update on Phase II clinical trial with drug candidate Namodenoson
June 20, 2018 - KIYATEC enrolls first patients with solid tumors in clinical study of its EV3D drug response assay
June 20, 2018 - Study finds growing support to allow pharmacists to write prescriptions
June 20, 2018 - Italian innovative SME receives 2.5 million Euro from RedSeed Ventures
June 20, 2018 - AHA: Kids Can Drown Quickly and Silently, So Prevention Is Key
June 20, 2018 - Continuous glucose monitors proven cost-effective, add to quality of life for diabetics
June 20, 2018 - Researchers use droplet-sized ‘miniecosystems’ to test therapeutic potential of molecules
June 20, 2018 - New approach could provide objective and easy-to-obtain measure of dietary adherence
June 20, 2018 - Dual-therapy approach can help boost motor recovery in stroke victims
June 20, 2018 - ‘Miracle treatment’ long-term success for babies with diabetes
June 20, 2018 - Rheumatoid Arthritis patients with depression have increased risk of disease flare
June 20, 2018 - NTU launches new research centers to prevent and treat diseases affecting Singaporeans
June 20, 2018 - Merck enters into agreement with HistoCyte Laboratories to distribute cell line reference products
June 20, 2018 - Researchers examine risk factors for opioid dependence in patients undergoing surgery for DS
June 20, 2018 - Study finds substantial variation in cardiovascular risk across India
June 20, 2018 - Kidney donation among carefully-selected older adults poses minimal risks
June 20, 2018 - Effects of atrial fibrillation can be reduced or reversed by losing weight
June 20, 2018 - Allergan’s Oral CGRP Receptor Antagonist Atogepant Demonstrates Robust Efficacy and Safety in Episodic Migraine Prevention in a Phase 2b/3 Clinical Trial
June 20, 2018 - The novel insights of proteoglycans in mineralized tissues
June 20, 2018 - Scientists shed light on key aspect of healthy cell division
June 20, 2018 - Circulating bone turnover markers not linked to hip fracture risk, shows study
June 20, 2018 - Scientists obtain key information about proteins from single human cells
June 20, 2018 - Scientists identify novel genes linked with infantile forms of schizophrenia
June 20, 2018 - Low-dose aspirin could help pregnant women with high blood pressure avoid a dangerous condition
June 20, 2018 - Unusual gene provides novel insight into how the brain wires itself
June 20, 2018 - Study finds IV acetaminophen to be no more effective than oral counterpart for colectomy patients
June 20, 2018 - MAARA to celebrate its 50th anniversary with lecture titled ‘The Future of Asthma’
June 20, 2018 - Administration eases way for small businesses to buy insurance in bulk
June 20, 2018 - High-Quality Diet May Decrease Mortality Risk in Cancer Survivors
June 20, 2018 - JAMA editorial on ECG screening and cardiac risks
June 20, 2018 - Study hints at benefits of lifestyle interventions in reducing dementia risk
June 20, 2018 - Low blood levels of vitamin D linked to increased risk of interstitial lung disease
June 20, 2018 - Simple cognitive task after brain injury improves memory function, study finds
June 20, 2018 - Clinical trial targets metastatic colorectal cancer with new combination therapy
June 20, 2018 - Researchers discover pesticide-free way to limit mosquitoes and reduce spread of West Nile virus
June 20, 2018 - Persistent psychological stress contributes to development and progression of vision loss
June 20, 2018 - Study introduces novel strategy to obtain reasonable drug cost estimates for cost-effectiveness analyses
June 20, 2018 - Does Salt Water Help Your Cut? And Other Health Myths of Summer
June 20, 2018 - Scientists help identify genetic markers for prostate cancer in global DNA download
June 19, 2018 - Common ingredient in toothpaste and hand wash could contribute to antibiotic resistance
June 19, 2018 - WHO launches multiyear campaign to eliminate use of trans fat
June 19, 2018 - Scientists could build better drugs by learning from bacteria-derived molecules
June 19, 2018 - Comparative silence between firing spikes of neurons reveals what they are really up to
June 19, 2018 - JAK inhibitors associated with aggressive lymphoma
June 19, 2018 - SetPoint announces positive long-term results of bioelectronic medicine to treat rheumatoid arthritis
June 19, 2018 - Hypnosis may help reduce fear, anxiety in children undergoing treatment for cancer
June 19, 2018 - Scientists point to potentially promising treatment target for deadly brain cancers
June 19, 2018 - After opioid overdose, only 30 percent get medicine to treat addiction
June 19, 2018 - Patients with mild Alzheimer’s disease over age 65 continue to derive benefit from DBS-f treatment
June 19, 2018 - Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis
June 19, 2018 - Paratek Presents New Analysis from Combined Phase 3 Skin Infection Studies Highlighting Efficacy of Omadacycline in Treating Drug Resistant S. aureus
June 19, 2018 - Autism is not linked to eating fish in pregnacy
June 19, 2018 - Scientists create universal assembly method to enhance cancer therapy and diagnostics
June 19, 2018 - Follow-up study confirms success of physiological test for autism
June 19, 2018 - FDA provides guidance on Novus Therapeutics’ development path for OP-02 to treat otitis media
June 19, 2018 - Scientists discover new mechanism controlling multiple sclerosis risk
June 19, 2018 - Award granted to Neem Biotech to develop antimicrobial intervention for chronic lung infections
June 19, 2018 - Study finds combined risk of death and developing cancer to be lowest in light drinkers
June 19, 2018 - Novel app teaches users how to stop life-threatening bleeding and save lives
June 19, 2018 - Single blood sample can provide adequate confirmation of diabetes
June 19, 2018 - New stimulation method increases hope for improving disorders of consciousness
June 19, 2018 - FDA Issues Complete Response Letter for Duobrii (halobetasol propionate and tazarotene) Lotion
June 19, 2018 - Defining the biology of autism
June 19, 2018 - Researchers use optogenetics to shape tissues
June 19, 2018 - Scientists discover genetic causes underlying group of related infant cancers
June 19, 2018 - Innovative digital home testing kit benefits patients with kidney conditions
June 19, 2018 - New guidance on selection and evaluation of wearable devices for use in regulatory clinical trials
June 19, 2018 - Researchers understand the role of brain’s ‘reward circuit’ in autism spectrum disorder
June 19, 2018 - Researchers propose new strategy to combat micro-pollutants in water
June 19, 2018 - Illicit Opioid Trade Up With Restrictions on Hydrocodone
June 19, 2018 - New 3-D imaging analysis technique could lead to improved arthritis treatment
June 19, 2018 - Study finds increased risk of mortality in people with cold agglutinin disease in five years after diagnosis
June 19, 2018 - Psychologists can play important role in treating alcohol problems
June 19, 2018 - Study finds elevated risk of congenital defects in lithium-exposed infants
Risk Score May Reveal if Kids are Victims of Ill-Treatment

Risk Score May Reveal if Kids are Victims of Ill-Treatment

image_pdfDownload PDFimage_print

Action Points

  • A maltreatment risk score was able to identify which children were more likely to be in danger of post-neonatal death and hospitalization.
  • The “very high risk” group of children were more likely to have a single mother, a mother age <20, and to live in a family with high parenting demand.

A maltreatment risk score was able to identify which children were more likely to be in danger of post-neonatal death and hospitalization, researchers found.

Children who were flagged at the 10% and 20% risk thresholds had more than four times higher risk of post-neonatal mortality and and a higher risk of hospitalization, reported Rhema Vaithianathan, PhD, of Auckland University of Technology in New Zealand, and colleagues.

Prior research found “linked administrative data and predictive risk models” can be used to identify which children have a greater risk of abuse and neglect, they wrote in writing in Pediatrics.

“If children identified by a [predictive risk model] for maltreatment are at risk for negative health outcomes beyond simply child protection involvement, these families should be prioritized for a broader swath of higher intensity preventive services,” the authors wrote.

Researchers used the Integrated Child Dataset, a census for all live births in New Zealand from 2004 to 2011, which is also linked to health, welfare benefits, child protective services and criminal justice registers to determine a risk score for children born in 2011.

They estimated a child’s probability of being “a victim of maltreatment” by the age of 2 years, using the “predictors” of child characteristics and family background. Certain factors shown to be predictive of maltreatment risk included:

  • Preterm birth (prior to 37 weeks gestation)
  • Infant’s sex (girl)
  • High parenting demand (more than three children in the family, multiple birth children or multiple children ages <2 years)
  • Maternal characteristics, such as age <25 or age >35
  • Marital status (single)
  • Receipt of public income support
  • History of mental health or substance abuse
  • Criminal records in last 5 years

After ranking children according to their probability of maltreatment, they estimated mortality and injury rates by age 3 for the children with the highest probability of maltreatment. Researchers then examined the top 10% of the risk score distribution as “very high risk” and the top 20% as “high risk.”

The “very high risk” group of children were more likely to have a single mother, a mother age <20, and to live in a family with high parenting demand. Not surprisingly, past or current child protective services involvement was "more prevalent" among "very high risk" children. Similar patterns were seen among the top 20%, or the "high risk" group of children.

Overall, children in the “very high risk” group were 4.8 times more likely to die in infancy (95% CI 3.2-7.2) versus other children. Their relative risk ratio was 9.0 for injury deaths overall (95% CI 3.9-20.7), the authors said, albeit with an extremely wide confidence interval.

The “very high risk” group was also two times as likely (95% CI 1.8-2.2) to be hospitalized versus other children, and hospitalizations for long bone fractures by age 2 was 2.6 times more likely to occur among this group (95% CI 1.7-4.0).

In an accompanying editorial, Brett Drake, PhD, and Melissa Jonson-Reid, PhD, both of Washington University in St. Louis, characterized this as a “breakthrough” in using predictive risk modeling to predict negative child outcomes.

“Until now, preventive services have been parent-initiated or from a hotline referral. This system breaks down relative to child fatalities because most fatalities happen early,” the editorialists wrote. “Creating such a program in the United States … would represent a paradigmatic change in how we see the role of the state in protecting children and supporting families, supplementing the current hotline-gated system with an empirically sound and timely, preventive system.”

Study limitations included some potential problems with data linkage and that the analysis was limited only to children in New Zealand, and not the immigrant children born into the country. Also, the researchers only looked at outcomes into early childhood, so the results would not be generalizable to outcomes at older ages.

Vaithianathan and co-authors, as well as Drake and Jonson-Reid, disclosed no relevant relationships with industry.

  • Reviewed by
    Robert Jasmer, MD Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner

1969-12-31T19:00:00-0500

last updated

Tagged with:

About author

Related Articles