Breaking News
March 23, 2019 - Lung cancer survivor recounts her lifetime struggles
March 23, 2019 - Radial and femoral approach for PCI achieve similar results in terms of survival
March 23, 2019 - Study sheds light on the optimal timing of coronary angiography in NSTEMI patients
March 23, 2019 - Excess hormones could cause a condition that can lead to blindness in women, study finds
March 23, 2019 - Dramatic shifts in first-time opioid prescriptions bring hope, concern
March 23, 2019 - Antidepressant drugs may not work when neurons are out of shape
March 23, 2019 - TTUHSC El Paso to establish endowed chair in neurology through a major grant
March 23, 2019 - New device approved by FDA for treating patients with moderate-to-severe heart failure
March 23, 2019 - People with peripheral artery disease have lower Omega-3 Index, shows research
March 23, 2019 - Trigger warnings have minimal impact on how people respond to content, shows research
March 23, 2019 - Gilead Announces Data From Two Studies Supporting Further Development of GS-6207, a Novel, Investigational HIV-1 Capsid Inhibitor as a Component of Future Long-Acting HIV Therapies
March 23, 2019 - Selfish genetic elements amplify inflammation and age-related diseases
March 23, 2019 - Study provides new understanding of how the brain recovers from damage caused by stroke
March 23, 2019 - CRISPR/Cas libraries could revolutionize drug discovery
March 23, 2019 - Allergic reaction during pregnancy may alter sexual-development in offspring’s brain
March 23, 2019 - Seeing through a robot’s eyes helps those with profound motor impairments
March 23, 2019 - Recent research shows that ease of breastfeeding after C-section differs culturally
March 23, 2019 - Newly discovered parameters offer more control over efficient release of drugs
March 23, 2019 - ‘De-tabooing’ of abortion- Women would like more support from health care community
March 23, 2019 - Anti-TB drugs can increase susceptibility to Mtb reinfection
March 23, 2019 - New survey indicates need of attention to neglected tropical diseases
March 23, 2019 - Innovative in vitro method to develop easy-to-swallow medicine for children and older people
March 23, 2019 - Sugary drinks could raise risk of early deaths finds study
March 23, 2019 - Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes
March 23, 2019 - Overall, Physicians Are Happy and Enjoy Their Lives
March 23, 2019 - Researchers discover how blood vessels protect the brain during inflammation
March 23, 2019 - CDC study shows modest improvement in optimal hospital breastfeeding policy
March 23, 2019 - Family-based prevention program to reduce alcohol use among older teens
March 23, 2019 - Remote monitoring of implanted defibrillators in heart failure patients prevents hospitalizations
March 23, 2019 - Appropriate doffing of personal protective equipment may reduce healthcare worker contamination
March 23, 2019 - Window screens can suppress mosquito populations, reduce malaria in Tanzania
March 23, 2019 - Researchers discover new biomarker for postoperative liver dysfunction
March 23, 2019 - Pregnancy history may be linked to cognitive function in older women, finds study
March 23, 2019 - Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack
March 23, 2019 - FDA Approves First Drug for Postpartum Depression, Zulresso (brexanolone)
March 23, 2019 - New guidelines outline new treatment management for psoriasis
March 23, 2019 - Thermally abused cooking oil may promote progression of breast cancer
March 23, 2019 - High-fructose corn syrup fuels growth of colon tumors in mice
March 23, 2019 - Partnership aims at establishing best practices to promote diversity in clinical trials
March 23, 2019 - New study examines presence of microbes in tap water from residences, office buildings
March 23, 2019 - Early life trauma may affect brain structure, contribute to major depressive disorder
March 23, 2019 - NIH starts clinical trial of drug to treat cravings associated with opioid use disorder
March 23, 2019 - Cervix bacteria, immune factors could be a warning signal of premature birth, reports new research
March 23, 2019 - Worst-ever emergency care performance figures underscore the need to focus on staffing
March 23, 2019 - The Current issue of “The view from here” is concerned with Cancer
March 23, 2019 - Mouse model validates how ‘good’ and ‘bad’ bacteria affect acne
March 23, 2019 - Individual amygdala neurons respond to touch, imagery and sounds
March 23, 2019 - Combination of two topical creams can prevent cancer
March 23, 2019 - Study suggests depression screening when assessing African-Americans for schizophrenia
March 23, 2019 - New electronic support system for choosing drug treatment based on patient’s genotype
March 23, 2019 - First-of-its-kind study provides pregnancy statistics of imprisoned U.S. women
March 23, 2019 - Marinus Pharmaceuticals Initiates Phase 3 Study in Children with PCDH19-Related Epilepsy
March 23, 2019 - Laparoscopy: MedlinePlus Lab Test Information
March 23, 2019 - Shellfish allergies: can they be treated?
March 23, 2019 - Toilet seat heart monitoring system
March 23, 2019 - Researchers identify way to improve common treatment for PTSD
March 23, 2019 - High potency cannabis use linked to psychosis finds study
March 23, 2019 - Evoke Pharma Submits Response to FDA Review Letter for Gimoti NDA
March 23, 2019 - Tracking HIV’s ever-evolving genome in effort to prioritize public health resources
March 23, 2019 - Scientists grow most sophisticated brain organoid to date
March 23, 2019 - ADHD drug raising risk of psychosis
March 22, 2019 - FDA approves brexanolone, first drug developed to treat postpartum depression
March 22, 2019 - Gruesome cat and dog experiments by the USDA exposed
March 22, 2019 - Ball pits used in children’s physical therapy may contribute to germ transmission
March 22, 2019 - Long-term use of inexpensive weight-loss drug may be safe and effective
March 22, 2019 - FDA Approves Sunosi (solriamfetol) for Excessive Daytime Sleepiness Associated with Narcolepsy or Obstructive Sleep Apnea
March 22, 2019 - Anti-Müllerian Hormone Test: MedlinePlus Lab Test Information
March 22, 2019 - Finding the right exercise, diet aids for HIV patients
March 22, 2019 - Health Plans For State Employees Use Medicare’s Hammer On Hospital Bills
March 22, 2019 - Researchers develop new tool for imaging large groups of neurons in living animals
March 22, 2019 - Certain bacteria and immune factors in vagina may cause or protect against preterm birth
March 22, 2019 - Research identifies guidelines for prioritizing hepatitis C treatment in U.S. prisons
March 22, 2019 - Novel breath test could pave new way to non-invasively measure gut health
March 22, 2019 - Pharmaceutical and personal care products may result in new contaminants in waterways
March 22, 2019 - New model could revolutionize the way researchers investigate spread of pathogens
March 22, 2019 - MSU professor receives NSF CAREER grant for biosensor diagnostics
March 22, 2019 - High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring
March 22, 2019 - ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib
March 22, 2019 - Wiedemann-Rautenstrauch syndrome – Genetics Home Reference
March 22, 2019 - Health insurance is not assurance of healthcare
Scoliosis surgery improves quality of life for children with severe cerebral palsy

Scoliosis surgery improves quality of life for children with severe cerebral palsy

image_pdfDownload PDFimage_print

For children with severe cerebral palsy (CP), surgery for scoliosis (sideways curvature of the spine) significantly improves the quality of life (QoL) for them and their caregivers, reports a study in the April 4, 2018, issue of The Journal of Bone & Joint Surgery. The journal is published in partnership with Wolters Kluwer.

“Scoliosis surgery in patients with CP leads to a significant improvement in health-related QoL, which is maintained five years following surgery,” write Firoz Miyanji, MD, of British Columbia Children’s Hospital, Vancouver, and colleagues from seven other North American medical centers. Their study provides evidence that surgery for scoliosis improves outcomes important to severely disabled children with CP and their parents/caregivers-;outweighing the substantial rate of complications during the first year after surgery.

Scoliosis Surgery Improves Quality of Life for Kids with Severe CP

The study included 69 children with CP who underwent spinal fusion surgery for scoliosis between 2008 and 2011, identified from an international database. The children all had at least five years’ follow-up up data; average age at the time of scoliosis surgery was about 13 years.

All of the children were severely disabled due to CP: most were in level V of the standard five-level Gross Motor Function Classification System. Up to 35 percent of children in levels IV and V will develop progressive scoliosis that cannot be controlled by wearing a brace. The abnormal spinal curvature causes a wide range of problems, including inability to balance in a seated position, pain, and possibly long-term adverse effects on lung, heart, and gastrointestinal function.

Surgery may be performed to stop scoliosis progression. However, the true benefits of surgery in improving QoL are difficult to quantify in these complex cases. Dr. Miyanji and colleagues used a validated questionnaire specifically designed for evaluation of children with severe CP-;the Caregiver Priorities and Child Health Index of Life with Disabilities, or “CPCHILD”-;to assess the impact of scoliosis surgery at one, two, and five years postoperatively.

Scoliosis surgery significantly reduced the spinal curvature. On a standard x-ray measurement (Cobb angle), the curve was reduced from the severe to the mild-to-moderate range, on average. The improvement remained stable through two and five years after surgery.

Analysis of the CPCHILD scores showed improvements QoL for the patients with CP and their caregivers. In addition to improvement in the total CPCHILD score, there were improvements in the areas of personal care, positioning, and comfort. Overall, 92 percent of caregivers reported that their child’s QoL was better one year after scoliosis surgery. Like the x-ray improvements, the gains in QoL persisted throughout follow-up.

As in previous studies of scoliosis surgery in children with CP, complications were common. This was especially so during the first year after surgery, when 46 percent of patients experienced a complication, most commonly pneumonia and surgical site infections. However, the first-year complications had little or no impact on QoL outcomes.

Surgery has been regarded as the standard of care for children with severe CP and scoliosis that cannot be controlled by bracing or seating modifications. However, the true benefits of scoliosis surgery-;especially in terms of “patient-centered outcomes” important to the children and their caregivers-;have been debated.

Some researchers have questioned the long-term benefits of scoliosis surgery in this group of patients-;especially considering the substantial risk of complications. “We are encouraged that the results of this multi-center study will provide patients, caregivers, and treating surgeons some guidance when faced with the decision of moving ahead with surgery,” says Dr. Miyanji.

“I am pleased to see that the data could provide useful information which helps patients with CP and their parents make good decisions,” comments Dr. Paul Sponseller, a coauthor of the study. “These families place an enormous amount of trust in our recommendations and this helps to give the advice a more solid basis, which they deserve.”​

Source:

https://wolterskluwer.com/

Tagged with:

About author

Related Articles