Breaking News
May 22, 2018 - CSIRO study urges Australians to avoid junk protein foods for healthy weight loss
May 22, 2018 - Breath Test Shows Promise for Diagnosis of Esophagogastric CA
May 22, 2018 - Common class of drugs linked to dementia even when taken 20 years before diagnosis
May 22, 2018 - Optimal Biomarker Frequency for Biosensors
May 22, 2018 - Ethics of conducting clinical research during public health emergencies
May 22, 2018 - FDA Approves Aimovig (erenumab), The First Drug Aimed at Preventing Migraines
May 22, 2018 - Warning labels on alcohol containers highly deficient, new research shows
May 22, 2018 - Doctors publish comprehensive proposal to ensure universal access to safe, affordable medications
May 22, 2018 - When is insurance not really insurance? When you need pricey dental care.
May 22, 2018 - Thyroid tumors may be more susceptible to precisely targeted radiation treatment, suggests study
May 22, 2018 - Researchers uncover clues to early lung transplant failure
May 22, 2018 - Coagulation Factor Tests: MedlinePlus Lab Test Information
May 22, 2018 - Booze ads cause risky drinking in young people
May 22, 2018 - Are you and your primary care doc ready to talk about your DNA?
May 22, 2018 - UCI research team uncovers new unexpected mode of neurotransmitter-based communication
May 22, 2018 - Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity
May 22, 2018 - Researchers highlight need for transgender-inclusive healthcare providers
May 22, 2018 - Celgene to share new and updated data around novel hematological therapies
May 22, 2018 - Scientists identify cell types underlying schizophrenia
May 22, 2018 - ACR urges legislative action on access and cost barriers in rheumatologic care
May 22, 2018 - Study examines link between nicotine dependence and likelihood to quit smoking after lung cancer screening
May 22, 2018 - New report highlights danger of childhood drowning in open water
May 22, 2018 - Proposed definition of patient-centeredness and engagement in healthcare
May 22, 2018 - Scientists reveal likely cause of childhood leukaemia
May 22, 2018 - Specific patterns of fat distribution linked to metabolic disease, shows study
May 22, 2018 - Novel drug prevents memory impairment in mice exposed to simulated deep space radiation
May 22, 2018 - New LIVE scoring tool effectively predicts future risk of hospitalization for COPD patients
May 22, 2018 - Most people with preclinical signs of Alzheimer’s disease may not develop dementia
May 22, 2018 - Fetal MRI can accurately identify holoprosencephaly by 18 weeks of gestation
May 22, 2018 - Multidisciplinary clinic can provide quality care for low-income patients with lung conditions
May 22, 2018 - Researchers create tool to determine patient’s response to immunotherapy drugs
May 22, 2018 - Pfizer starts Phase 1/2 study of RSV vaccine candidate in healthy adult volunteers
May 22, 2018 - New technique allows researchers to control heart cells growing in a dish
May 22, 2018 - FDA Approves Lokelma (sodium zirconium cyclosilicate) for the Treatment of Adults with Hyperkalemia
May 22, 2018 - Making America’s doctors look more like America
May 22, 2018 - Few parents use simple strategies to protect kids from food poisoning, reports study
May 22, 2018 - Reduction in heart disease risk factors could help prevent frailty among older adults
May 22, 2018 - Study finds age-related racial disparities in youth suicide
May 22, 2018 - Childhood leukemia linked to lack of childhood infections
May 22, 2018 - Scientists identify new drug target to combat chikungunya virus
May 22, 2018 - PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels
May 22, 2018 - Celltrion Healthcare advocates early introduction of biologics for patients to improve clinical outcomes
May 22, 2018 - Local anesthetic drug not linked to reduction in opioid use, complications after knee surgery
May 22, 2018 - FDA Alert: Keytruda (pembrolizumab) or Tecentriq (atezolizumab): FDA Alerts Health Care Professionals and Investigators: FDA Statement
May 22, 2018 - Post-surgical opioids can, paradoxically, lead to chronic pain
May 22, 2018 - Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal
May 22, 2018 - Nipah virus kills nine in Kerala, India
May 22, 2018 - Higher body temperatures speed the bodies’ responses to infections and tumors, finds research
May 22, 2018 - Staying up all night, sleeping all day can swiftly impact over 100 proteins in the blood
May 22, 2018 - Combination of vascular risk and brain amyloid levels may accelerate age-related cognitive decline
May 22, 2018 - ASCO: Few Eligible Smokers Had CT Screen for Lung CA in 2016
May 22, 2018 - In Brazil, patients risk everything for the ‘right to beauty’
May 22, 2018 - Women with gestational diabetes may be at greater risk for chronic kidney disease
May 22, 2018 - Flavonoid intake may reduce lung function decline that occurs with aging
May 22, 2018 - AACN brings together over thousands of nurses for annual conference
May 22, 2018 - AHA: ‘Ideal’ Heart Health Eludes More Americans
May 22, 2018 - Drug used to treat daytime sleepiness does not appear to improve driving in those with sleep apnea
May 22, 2018 - Incorporation of AI could transform cancer diagnosis in UK
May 22, 2018 - Neurological protein found to protect against inflammatory diseases
May 22, 2018 - Lipoprotein (a) Blood Test: MedlinePlus Lab Test Information
May 22, 2018 - A new molecular target identified in depression
May 22, 2018 - Researchers discover new gene locations that determine heart’s response to exercise
May 21, 2018 - HCM mutation prevents the heart from increasing pumping force, study shows
May 21, 2018 - Intelligent brains possess fewer neuronal connections, finds study
May 21, 2018 - UA physicians developing new tool to detect urethral blockage
May 21, 2018 - Fish-eating habits of pregnant women not linked to autistic traits in their children
May 21, 2018 - Shingrix Shingles Vaccination | What You Should Know
May 21, 2018 - Early depression diagnosis is deadly serious for patients with coronary artery disease
May 21, 2018 - Reducing exposure to hormone interfering chemicals may mitigate obesity risk
May 21, 2018 - Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients
May 21, 2018 - FDA Approves Aimovig (erenumab-aooe) as a Preventive Treatment for Migraine
May 21, 2018 - Infant death study reveals dangerous sleep practices among babysitters, relatives, others
May 21, 2018 - Intermittent fasting may increase diabetes risk, shows study
May 21, 2018 - Increase in local temperature correlates with higher degree of antibiotic resistance, finds study
May 21, 2018 - Treg infusions show promise in slowing progression of ALS
May 21, 2018 - New study shows declines in prostate cancer screening, diagnoses and treatment
May 21, 2018 - Fasting diets could raise risk of diabetes say experts
May 21, 2018 - FDA Alert: 7K and Poseidon 4500 by Shoreside Enterprises: Voluntary Recall
May 21, 2018 - Cell phones at summer camp: Research explores the effects
May 21, 2018 - Birth rate decline driven by waiting longer to have children, cost of infertility treatment
Smart technology helps improve outcomes for patients with head and neck cancer

Smart technology helps improve outcomes for patients with head and neck cancer

image_pdfDownload PDFimage_print

ASCO Perspective

“This study demonstrates the power of leveraging smart technology to improve the care of people with cancer. These tools helped simplify care for both patients and their care providers by enabling emerging side effects to be identified and addressed quickly and efficiently to ease the burden of treatment. I hope that these or similar technologies will be broadly available to patients soon,” said ASCO President Bruce E. Johnson, MD, FASCO.

A federally funded, randomized clinical trial of 357 people receiving radiation for head and neck cancer, using mobile and sensor technology to remotely monitor patient symptoms, resulted in less severe symptoms related to both the cancer and its treatment (both general and cancer-related).

Patients who used the technology – which included a Bluetooth-enabled weight scale, Bluetooth-enabled blood pressure cuff, and mobile tablet with a symptom-tracking app that sent information directly to their physician each weekday – had lower symptom severity than participants who had standard weekly visits with their doctors.

In addition, daily remote tracking of patient wellbeing, according to the researchers, enabled physicians to detect concerning symptoms early and respond more rapidly, compared to usual care. These findings will be presented at the upcoming 2018 ASCO Annual Meeting in Chicago.

“Our study generated evidence on how newer technologies can be integrated into cancer care relatively easily and improve patient outcomes without interfering too much in a person’s daily life,” said lead study author Susan K. Peterson, PhD, professor, Department of Behavioral Science, The University of Texas MD Anderson Cancer Center, Houston. “This study was done during a rather intense period in the patients’ care for head and neck cancer. The system helped their physicians to provide valuable support that ultimately resulted in lower symptom severity.”

About Head and Neck Cancer

An estimated 51,540 new head and neck cancers will be diagnosed in the United States in 2018.1 Just over 10,000 people are expected to die of the disease, with men accounting for three-quarters of these deaths.

Most people diagnosed with this form of cancer receive radiation therapy but can also have chemotherapy or surgery. One of the major side effects of treatment that requires careful monitoring is pain and difficulty swallowing, which can lead to dehydration.

About the Study

This trial used a technology system called CYCORE (CYberinfrastructure for COmparative Effectiveness REsearch), developed collaboratively by four institutions through a grant from the National Cancer Institute.

Participants were randomly assigned to CYCORE (169 people) or usual care (188 people), which consisted of weekly doctor visits. People in the CYCORE group received sensors (blood pressure cuffs and weight scales) that were Bluetooth-enabled. They also got mobile tablets with proprietary Wi-Fi. An in-home wide area network (WAN) hub/router transmitted their sensor readouts, and a mobile app transmitted their symptom data through a back-end cyber-infrastructure to secure firewall-protected computers at MD Anderson to ensure patient information confidentiality.

For the CYCORE group, physicians reviewed data from the app and sensor transmissions remotely each weekday and could intervene in a person’s care if necessary. Both CYCORE and usual care participants had weekly in-person doctor visits.

At the start of radiation therapy, study participants completed a 28-item MD Anderson Symptom Inventory survey about their health and common activities of daily living. The survey covered general symptoms that are common in people with cancer, such as pain, fatigue, and nausea, as well as symptoms that are particularly relevant to people with head and neck cancer, such as difficulty swallowing or chewing, skin pain/burning/rash, and problems with tasting food. The participants completed a similar survey at the end of their radiation therapy, usually 6 to 7 weeks later. A final survey was completed 6 to 8 weeks after their radiation therapy ended.

Key Findings

There was no difference in self-reported health severity scores between the CYCORE participants and those who received usual care at the start of the trial. Symptoms severity was scored on a scale of 0 to 10, with zero being no symptom or pain and 10 being the highest level of symptom severity. After completion of radiation therapy, the CYCORE participants had lower (i.e. better) mean scores for general symptoms vs. usual care participants (2.9 vs. 3.4), as well as lower mean scores for symptoms specific to head and neck cancer (4.2 vs. 4.8).

Six to 8 weeks after completion of therapy, CYCORE participants had a mean score of 1.6 vs. 1.9 for usual care participants based on overall health. Both groups had slightly higher severity scores for specific head and neck symptoms (1.7 vs. 2.1).

Most patients (80% or more) adhered to daily monitoring, which was an excellent outcome given the intensity of their treatments, noted Dr. Peterson. Scores reflecting how various symptoms interfered in activities of daily living were about the same in both groups across the entire time of survey reporting.

Limitations and Next Steps

While the authors were able to recruit people from a wide range of ages, the study population was mostly white, which closely reflected the overall head and neck patient population at the cancer center. The next step for researchers may be to determine how long the benefit of a CYCORE intervention could persist. They also hope to implement the CYCORE intervention in non-academic cancer treatment settings where the majority of cancer patients receive their treatment.

Source:

https://www.asco.org/about-asco/press-center/news-releases/use-mobile-and-sensor-technology-lowers-symptom-severity

Tagged with:

About author

Related Articles