Breaking News
May 3, 2019 - Vaping and Smoking May Signal Greater Motivation to Quit
May 3, 2019 - Dementia looks different in brains of Hispanics
May 3, 2019 - Short-Staffed Nursing Homes See Drop In Medicare Ratings
May 3, 2019 - Study of teens with eating disorders explores how substance users differ from non-substance users
May 3, 2019 - Scientists develop new video game that may help in the study of Alzheimer’s
May 3, 2019 - Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium
May 3, 2019 - Cornell University study uncovers relationship between starch digestion gene and gut bacteria
May 3, 2019 - How to Safely Use Glucose Meters and Test Strips for Diabetes
May 3, 2019 - Anti-inflammatory drugs ineffective for prevention of Alzheimer’s disease
May 3, 2019 - Study tracks Pennsylvania’s oil and gas waste-disposal practices
May 3, 2019 - Creating a better radiation diagnostic test for astronauts
May 3, 2019 - Vegans are often deficient in these four nutrients
May 3, 2019 - PPDC announces seed grants to develop medical devices for children
May 3, 2019 - Study maps out the frequency and impact of water polo head injuries
May 3, 2019 - Research on Reddit identifies risks associated with unproven treatments for opioid addiction
May 3, 2019 - Good smells may help ease tobacco cravings
May 3, 2019 - Medical financial hardship found to be very common among people in the United States
May 3, 2019 - Researchers develop multimodal system for personalized post-stroke rehabilitation
May 3, 2019 - Study shows significant mortality benefit with CABG over percutaneous coronary intervention
May 3, 2019 - Will gene-editing of human embryos ever be justifiable?
May 3, 2019 - FDA Approves Dengvaxia (dengue vaccine) for the Prevention of Dengue Disease in Endemic Regions
May 3, 2019 - Why Tonsillitis Keeps Coming Back
May 3, 2019 - Fighting the opioid epidemic with data
May 3, 2019 - Maggot sausages may soon be a reality
May 3, 2019 - Deletion of ATDC gene prevents development of pancreatic cancer in mice
May 2, 2019 - Targeted Therapy Promising for Rare Hematologic Cancer
May 2, 2019 - Alzheimer’s disease is a ‘double-prion disorder,’ study shows
May 2, 2019 - Reservoir bugs: How one bacterial menace makes its home in the human stomach
May 2, 2019 - Clinical, Admin Staff From Cardiology Get Sneak Peek at Epic
May 2, 2019 - Depression increases hospital use and mortality in children
May 2, 2019 - Vicon and NOC support CURE International to create first gait lab in Ethiopia
May 2, 2019 - Researchers use 3D printer to make paper organs
May 2, 2019 - Viral infection in utero associated with behavioral abnormalities in offspring
May 2, 2019 - U.S. Teen Opioid Deaths Soaring
May 2, 2019 - Opioid distribution data should be public
May 2, 2019 - In the Spotlight: “I’m learning every single day”
May 2, 2019 - 2019 Schaefer Scholars Announced
May 2, 2019 - Podcast: KHN’s ‘What The Health?’ Bye-Bye, ACA, And Hello ‘Medicare-For-All’?
May 2, 2019 - Study describes new viral molecular evasion mechanism used by cytomegalovirus
May 2, 2019 - SLU study suggests a more equitable way for Medicare reimbursement
May 2, 2019 - Scientists discover first gene involved in lower urinary tract obstruction
May 2, 2019 - Researchers identify 34 genes associated with increased risk of ovarian cancer
May 2, 2019 - Many low-income infants receive formula in the first few days of life, finds study
May 2, 2019 - Global study finds high success rate for hip and knee replacements
May 2, 2019 - Taking depression seriously: What is it?
May 2, 2019 - With Head Injuries Mounting, Will Cities Put Their Feet Down On E-Scooters?
May 2, 2019 - Scientists develop small fluorophores for tracking metabolites in living cells
May 2, 2019 - Study casts new light into how mothers’ and babies’ genes influence birth weight
May 2, 2019 - Researchers uncover new brain mechanisms regulating body weight
May 2, 2019 - Organ-on-chip systems offered to Asia-Pacific regions by Sydney’s AXT
May 2, 2019 - Adoption of new rules drops readmission penalties against safety net hospitals
May 2, 2019 - Kids and teens who consume zero-calorie sweetened beverages do not save calories
May 2, 2019 - Improved procedure for cancer-related erectile dysfunction
May 2, 2019 - Hormone may improve social behavior in autism
May 2, 2019 - Alzheimer’s disease may be caused by infectious proteins called prions
May 2, 2019 - Even Doctors Can’t Navigate Our ‘Broken Health Care System’
May 2, 2019 - Study looks at the impact on criminal persistence of head injuries
May 2, 2019 - Honey ‘as high in sugars as table sugar’
May 2, 2019 - Innovations to U.S. food system could help consumers in choosing healthy foods
May 2, 2019 - FDA Approves Mavyret (glecaprevir and pibrentasvir) as First Treatment for All Genotypes of Hepatitis C in Pediatric Patients
May 2, 2019 - Women underreport prevalence and intensity of their own snoring
May 2, 2019 - Concussion summit focuses on science behind brain injury
May 2, 2019 - Booker’s Argument For Environmental Justice Stays Within The Lines
May 2, 2019 - Cornell research explains increased metastatic cancer risk in diabetics
May 2, 2019 - Mount Sinai study provides fresh insights into cellular pathways that cause cancer
May 2, 2019 - Researchers to study link between prenatal pesticide exposures and childhood ADHD
May 2, 2019 - CoGEN Congress 2019: Speakers’ overviews
May 2, 2019 - A new strategy for managing diabetic macular edema in people with good vision
May 2, 2019 - Sagent Pharmaceuticals Issues Voluntary Nationwide Recall of Ketorolac Tromethamine Injection, USP, 60mg/2mL (30mg per mL) Due to Lack of Sterility Assurance
May 2, 2019 - Screen time associated with behavioral problems in preschoolers
May 2, 2019 - Hormone reduces social impairment in kids with autism | News Center
May 2, 2019 - Researchers synthesize peroxidase-mimicking nanozyme with low cost and superior catalytic activity
May 2, 2019 - Study results of a potential drug to treat Type 2 diabetes in children announced
May 2, 2019 - Multigene test helps doctors to make effective treatment decisions for breast cancer patients
May 2, 2019 - UNC School of Medicine initiative providing unique care to dementia patients
May 2, 2019 - Nestlé Health Science and VHP join forces to launch innovative COPES program for cancer patients
May 2, 2019 - Study examines how our brain generates consciousness and loses it during anesthesia
May 2, 2019 - Transition Support Program May Aid Young Adults With Type 1 Diabetes
May 2, 2019 - Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death
May 2, 2019 - Research reveals complexity of how we make decisions
New non-invasive procedure to reposition kidney stones could benefit astronauts

New non-invasive procedure to reposition kidney stones could benefit astronauts

A new, painless, non-invasive procedure that harnesses ultrasound technology to reposition kidney stones, in an effort to offer the sufferer quick relief, will undergo testing in emergency patients.

The development and assessment of the new technology is led by University of Washington and UW Medicine, in collaboration with other universities and agencies.

Kidney stones are an increasingly common condition that affects 1 in 11 Americans during their lifetime. The condition is even more frequently encountered in astronauts during space missions. The hope is that the new technology could benefit astronauts as well as Earth-side patients.

The approach will be tested on in local patients at UW Medicine’s Harborview Medical Center and University of Washington Medical Center Emergency Departments.

Funding has been provided by the National Aeronautics and Space Administration (NASA), the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases and the Department of Defense’s Surgical Research Institute.

After the invention of an ultrasound device to better detect kidney stones, engineers from the Applied Physics Laboratory at the University of Washington observed that they could accurately reposition small objects with ultrasound on a laboratory table. In conjunction with partners in the UW School of Medicine urology, emergency medicine, and radiology departments, the researchers went on to advance the technology and to use the same waves from a hand held ultrasound transducer to re-locate kidney stones in preliminary tests.

The work has also led to a spin off company, SonoMotion, which is working to develop a commercial device for the same purposes of non-invasive kidney stone repositioning.

Every year more than 600 people in the throes of a kidney stone episode seek emergency care at Harborview and UW Medical Center in Seattle.

Kidney stones become symptomatic if they enter the urinary tract, have trouble passing, and become stuck where they can cause debilitating pain. In addition, obstruction of urine flow causes a backup. This can result in swelling of the kidney, and cramping in the ureter, thereby setting the stage for infection or further kidney damage.

Because space travel makes astronauts prone to kidney stones due, in part to bone demineralization from weightlessness, they are at increased risk.

The NASA evidence base and publications note that astronauts have had more than 30 instances of kidney stones within two years of space travel. Medical assistance is a formidable challenge for those orbiting this planet or heading to other solar system destinations.

“For this trial we will be trying to reposition obstructing stones for our emergency department patients,” said Dr. M. Kennedy Hall, assistant professor of emergency medicine, and co-principal investigator of the study along with Dr. Hunter Wessells, professor and chair of urology, both at the UW School of Medicine.

“Our hope is that we will be able to move stones back into patients’ kidneys.” Hall said, “This could make our patients more comfortable and allow them to deal with the kidney stone on their terms, not on the stone’s terms. An additional benefit of repositioning kidney stones is potentially avoiding unnecessary pain medications such as opioids for patients discharged from their kidney stone emergency.”

“We anticipate being able to reposition an acute stone to relieve pressure on the kidney. This would have the benefit of relieving suffering as well as avoiding emergent urologic intervention,” explained Wessells.

Their clinical research team will test a protocol that might be carried out safely and effectively during a space mission by on-board medical responders.

Michael Bailey, an ultrasound researcher at the UW Applied Physics Laboratory and one of the project leaders, emphasized, “This technology could give patients on Earth the ability to immediately return to normal life (in contrast to surgical treatments or continued, painful attempts to passing the stone). For astronauts in space, this option could save a life and allow astronauts to complete urgent mission responsibilities without having to turn the space shuttle around – a significant consideration.”

Bailey mentioned a past incident where a Russian cosmonaut who seemed to be experiencing a blocking kidney stone while in space.

The mission crew was preparing for emergency re-entry when it appeared that his stone finally passed.

The current rendition of the ultrasound kidney stone push technology has been coined the flexible ultrasound system, or FUS, and is about the size of a lecture podium on wheels. It has a built-in imaging screen and a hand-operated device for delivering the waves through the surface of the body.

If trials on Earth are successful, NASA would likely plan to fly the ultrasound system in future missions, including longer duration human explorations of Mars.

In addition to Hall, Wessells and Bailey, the research team includes: Drs. Jonathan Harper and Mathew Sorensen from the Department of Urology, and Dr. Martin Gunn from the Department of Radiology, all UW Medicine physicians.

Many others including staff and students at the UW Applied Physics Laboratory, investigators at the Surgical Outcomes Research Center in the Department of Surgery, the UW Medicine Institute of Translational Health Sciences, the UW CoMotion innovation hub collaborators from several other universities, UW Medicine residents, and many others are also contributing to the technology development, research, testing and assessment.

Source:

https://newsroom.uw.edu/news/keeping-kidney-stones-bay-during-space-flights

Tagged with:

About author

Related Articles