Breaking News
September 20, 2018 - Investigators find that bile acids reduce cocaine reward
September 20, 2018 - Cannabinoid drugs reduce perceived unpleasantness of painful stimuli and increase tolerance
September 20, 2018 - Geroscience takes center stage in Journal of the American Medical Association
September 20, 2018 - Ambient Particulate Matter Linked to Emergency Asthma Care
September 20, 2018 - Patient satisfaction with plastic surgery—it’s the surgeon, not the practice
September 20, 2018 - Medicine is a team sport – and that’s exactly how it should be
September 20, 2018 - Logos Biosystems releases new electrophoretic tissue clearing system with twice the features in half the space
September 20, 2018 - Novel micro-platform reveals never-before-seen behaviors of cancer cells
September 20, 2018 - PAREXEL partners with Datavant to enhance clinical study design and generate real-world evidence
September 20, 2018 - Robert Koch Institute publishes new data on allergies, mental health problems, and accident injuries
September 20, 2018 - Study finds higher readmission rates in for-profit hospitals
September 20, 2018 - Encouraging youth to do strength-based exercises could help tackle child obesity
September 20, 2018 - Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death
September 20, 2018 - Researchers find way to map mysterious content of non-coding RNA
September 20, 2018 - Air Pollutants Reach Placenta, Might Harm Fetus: Study
September 20, 2018 - Sleep apnea, congenital heart disease may be deadly mix for hospitalized infants
September 20, 2018 - My relative has cancer, should I worry? Encouraging cascade genetic testing
September 20, 2018 - Investigators determine specific treatable traits that can predict future asthma attacks
September 20, 2018 - More doctor visits can lower risk of suicide attempts in fibromyalgia patients
September 20, 2018 - Computer avatars play role in diagnosis of dementia
September 20, 2018 - Addition of CTLA4 targeted therapy to PD-1 targeted therapy may benefit patients with ovarian cancer
September 20, 2018 - ASPREE trial explores whether low dose aspirin can prolong good health in elderly people
September 20, 2018 - ATS publishes new guideline focused on weight loss strategies for sleep apnea patients
September 20, 2018 - The Current issue of “The view from here” is concerned with Drug Delivery
September 19, 2018 - Sleep apnea could favour tumor growth at young ages
September 19, 2018 - Stealth vaping fad hidden from parents, teachers
September 19, 2018 - Witnessing school violence linked to later risk of psycho-social and academic impairment
September 19, 2018 - Common household cleaners could make children overweight by changing gut microbiota
September 19, 2018 - Salk research in yeast leads to serendipitous finding about hypomyelinating leukodystrophy
September 19, 2018 - Study: Overweight or obese women may have increased risk of urinary incontinence
September 19, 2018 - Study shows how cellular waste disposal processes also promote inflammation
September 19, 2018 - New multidisciplinary microsurgery microscope, PROVIDO, introduced by Leica
September 19, 2018 - Phase 2b STORM Data Evaluating Selinexor in Patients with Penta-Refractory Multiple Myeloma Presented at the Society of Hematologic Oncology 2018 Annual Meeting
September 19, 2018 - Decisions recruiting gut feelings seen as reflection of true self, more assuredly held, study says
September 19, 2018 - How AI can improve end-of-life care
September 19, 2018 - UNIST and Ulsan initiate research collaboration to develop human organs-on-chips
September 19, 2018 - Study highlights key role of migrating shoals of fish in sustaining deep-ocean microorganisms
September 19, 2018 - Disagreeable individuals can benefit most from behaving more compassionately, finds study
September 19, 2018 - Janssen Submits New Drug Application to U.S. FDA Seeking Approval of Erdafitinib for the Treatment of Metastatic Urothelial Cancer
September 19, 2018 - Neuroplasticity is increased but dysregulated in the aging brain, study finds
September 19, 2018 - Suicide: A public health crisis
September 19, 2018 - Infants using popular anti-reflux medicines are not at increased risk of lung infections
September 19, 2018 - Stanford team will participate in NIH-funded study of tobacco policies | News Center
September 19, 2018 - Women with high levels of anti-Müllerian hormone more likely to develop breast cancer
September 19, 2018 - Researchers use larval zebrafish model to reveal role of locus coeruleus in anesthesia
September 19, 2018 - Effects of prematurity found to be more severe for the brains of males than females
September 19, 2018 - NIH funds CWRU to investigate new imaging approach for diagnosing peripheral arterial disease
September 19, 2018 - NUS researchers develop new device for quick and accurate screening of diseases
September 19, 2018 - Leading nutritionist explains about different types of iron in oral supplements
September 19, 2018 - New Crest Gum & Enamel Repair toothpaste may boost enamel repair and reverse gingivitis
September 19, 2018 - Analysis does not find any safety concerns of bivalent HPV vaccine
September 19, 2018 - Many Older Adults Transition to Long-Term Benzodiazepine Use
September 19, 2018 - Caregiving – resources – older adults: MedlinePlus Medical Encyclopedia
September 19, 2018 - Research shows that cystic fibrosis impacts growth in the womb
September 19, 2018 - Study shows how head, neck positioning affects concussion risk | News Center
September 19, 2018 - Antioxidant in green tea helps sneak therapeutic RNAs into cells
September 19, 2018 - Excess pregnancy weight gain affects cardiometabolic risk in offspring
September 19, 2018 - Penn researchers find common thread linking almost all TNR expansion diseases
September 19, 2018 - Ipsen receives approval from Health Canada for CABOMETYX tablets for treating renal cell carcinoma
September 19, 2018 - Researchers use CRISPR screen to reveal new targets in squamous cell carcinomas
September 19, 2018 - UGR to coordinate the European H2020 project focused on Smart Personalized Nutrition
September 19, 2018 - Mumps Spread Quickly at Texas Cheerleading Meets: Study
September 19, 2018 - Addressing child stunting in Pakistan is critical
September 19, 2018 - Innovative system makes hospitals, clinics accessible for people with visual impairments
September 19, 2018 - CXCL14 protein is secreted by brown adipose tissue and has beneficial effects in metabolic diseases
September 19, 2018 - Air pollution increases risk of dementia
September 19, 2018 - Inequality issues persist even under new U.S. kidney transplant allocation system
September 19, 2018 - New study reveals mechanisms that lead to cognitive decline in Type 2 diabetes
September 19, 2018 - FDA launches new comprehensive effort to educate kids about dangers of e-cigarettes
September 19, 2018 - Study reveals mechanism underlying plants’ ability to signal defense
September 19, 2018 - Researchers harness Zika virus vaccine under development to target glioblastoma
September 19, 2018 - Novel deep learning drug discovery platform gets £1 million innovation boost
September 19, 2018 - Sensor array may detect de novo Parkinson’s disease in breath
September 19, 2018 - A roadmap for the future of electronic health records
September 19, 2018 - Surprising research showing peptide adaptability may pave way to develop immunotherapies
September 19, 2018 - Amyloid β protein makes comeback as therapeutic target for Alzheimer’s disease
September 19, 2018 - Alcon expands its global support of eye care professionals through Alcon Experience Academy
September 19, 2018 - Study gives new insights into how cells leverage GPCRs to control inflammation
September 19, 2018 - Automatic relevance detection in ophthalmic surgery videos
September 19, 2018 - UNIST to accelerate discovery, development of new medicines for incurable diseases
NYU Langone’s Perlmutter Cancer Center expands Blood and Marrow Transplant Program

NYU Langone’s Perlmutter Cancer Center expands Blood and Marrow Transplant Program

image_pdfDownload PDFimage_print

To further advance the study and treatment of blood cancers, Perlmutter Cancer Center at NYU Langone Health has significantly expanded its Blood and Marrow Transplant Program.

The program performs autologous and allogeneic transplants in adults and autologous transplants in children to treat the full spectrum of blood-borne cancers, including leukemia, lymphoma, and multiple myeloma. It recently received certification from the Foundation for the Accreditation of Cellular Therapy (FACT) to perform adult allogeneic transplants.

Autologous transplants involve using a patient’s own blood and blood by-products, while allogeneic transplants use those of an appropriate donor.

The Blood and Marrow Transplant Program is led by nationally renowned hematologist–oncologist, Samer Al-Homsi, MD, MBA, who joined Perlmutter Cancer Center-;one of the 70 cancer centers across the country designated by the National Institutes of Health-;in June 2017 to lead the program. Just in the past 12 months, more than 70 patients have received blood and marrow transplants at Perlmutter Cancer Center, which are performed in the specially designed Rita J. and Stanley H. Kaplan Stem Cell and Bone Marrow Transplant Center, located in the brand-new Kimmel Pavilion on NYU Langone’s main campus in Manhattan.

Based on pioneering work done at Johns Hopkins Cancer Center, the Blood and Marrow Transplant Program also offers haploidentical transplantation to patients. Haploidentical transplantation vastly expands the potential donor pool for patients who require a transplant.

“Typically, when you do a transplant, you need to have a full tissue match between the donor and recipient. Alternatively, we can now use haploidentical, or ‘half-match,’ transplants,” Dr. Al-Homsi says. “This transplant option will go a long way in overcoming the limitations of finding the right donor. Patients who have difficulty finding perfect matches will have more options, meaning that we can treat their cancer more effectively.”

Transplantation uses healthy hematopoietic precursor cells, or stem cells, to help fight cancer and replace unhealthy bone marrow.

Dr. Al-Homsi also does research that focuses on preventing graft-versus-host disease, or GvHD, a potentially life-threatening complication of blood and marrow transplant. He has led clinical trials examining innovative combinations of medications to prevent GvHD, including cyclophosphamide and proteasome inhibitors. Such combinations can prevent the use of other extended and burdensome prophylactic traditional agents and are applicable to people with limited kidney function, who are often denied blood and marrow transplants.

The Blood and Marrow Transplant Program works closely with the Clinical Leukemia Program at Perlmutter Cancer Center, led by Raoul Tibes, MD, PhD. Dr. Al-Homsi evaluates leukemia patients who require transplantation after their initial treatment provided by the hematologist–oncologists in the leukemia program.

“The Clinical Leukemia and Blood and Marrow Transplant programs really go hand-in-hand, and care for many of the same patients,” says Dr. Tibes. “We take a collaborative approach, helping patients from their first visit through their entire treatment. In many ways, one program cannot be fully effective without the other, and vice versa.”

“Our understanding of hematologic malignancies has advanced greatly over the past decade, to the point that many blood-borne cancers are curable,” says Benjamin G. Neel, MD, PhD, director of Perlmutter Cancer Center. “Bone marrow transplantation plays a critical role in these advances. Dr. Al-Homsi’s research holds tremendous promise to curtail negative interactions between host and transplanted cells and make this form of treatment safer and more effective.”

Tagged with:

About author

Related Articles