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Many doctors in India miss TB signs: study

Many doctors in India miss TB signs: study

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Private sector health care providers, the first point of contact for 50-70 percent of patients with tuberculosis (TB) symptoms in India, are delivering a wide range of largely inadequate care to these patients according to a study published this week in PLOS Medicine. Credit: CDC, Amanda Mills

Many private sector doctors in India miss the signs of tuberculosis and therefore provide patients inadequate treatment, according to a new study published Tuesday involving people hired to act out the symptoms.

Tuberculosis or TB, an airborne infection, remains a major public health issue in India, China and Indonesia, among other countries.

It killed 1.7 million people in 2017, according to the World Health Organization, and a global health summit will be held at the United Nations on Wednesday to raise funds to eradicate the disease.

But the primary care physicians who see patients when they start coughing are the weak link in the fight against the pandemic—at least in the two cities where the study took place, the metropolis of Mumbai and eastern Patna.

The experiment was financed by the Bill and Melinda Gates Foundation and led by a team of researchers from McGill University, the World Bank and Johns Hopkins University. The results were published in PLOS Medicine.

It took place across 10 months between 2014 and 2015. Twenty-four “simulated patients” went to 1,288 private sector doctors, presenting symptoms ranging from a simple cough to a cough presented as a possible relapse.

‘Doing too little’

In 65 percent of interactions, medical practitioners—which includes both qualified doctors, unqualified ones and those who practice traditional medicine—responded in a manner inconsistent with Indian and international standards of care.

In some cases where a doctor suspected a problem linked to air pollution, they prescribed an antibiotic or syrup and asked the patient to return a few weeks later.

Doctors with formal medical training, particular in Mumbai, did slightly better, offering the correct course of treatment in roughly half of the cases, according to the results.

Doctors without formal training, who are very common in rural zones, are doing worse, as are those who provide traditional medicine including ayurveda, unani, and Siddha medicine, collectively known as “ayush.”

Jishnu Das, a World Bank economist, explained that the problem wasn’t so much that doctors were following one alternate treatment course as much as just doing “everything you can find.”

“Some guy is giving antibiotics and fluoroquinolone, somebody else is giving steroids and fluoroquinolone, somebody else is giving cough syrup and antibiotics,” Das said, explaining that such haphazard methods can harm patients, not to mention boost antibiotic resistance.

By 2040, 12.4 percent of TB cases in India will be multidrug-resistant strains, said one study published in 2017 in the medical journal The Lancet, especially as medications like antibiotics are easy to buy without a prescription there.

The most common mistake, according to Tuesday’s study, is that doctors simply do not order the tests necessary to make a diagnosis, such as testing lung fluid or a chest X-ray.

“Doctors are actually doing too little,” said Das. “They are not just picking up that the guy might have TB.”

On the bright side, doctors who make mistakes consistently make the same mistakes.

In theory, that “coherence” makes it possible to correct the pattern, if training was upgraded and harmonized.

In the near future, according to McGill professor Madhukar Pai, it’s vital to refer patients to the right doctors and provide them with subsidized public programs for the most effective anti-TB drugs—instead of sending them home with the wrong pills.

India’s overburdened public health system suffers from a lack of doctors and hospitals. Medical treatment is largely free in government-funded hospitals but long queues and poor service force many to seek private care.

The private sector provides almost 80 percent of outpatient care, and is the first point of contact for tuberculosis for 50 to 70 percent of patients.


Explore further:
‘Mystery clients’ reveal weaknesses of tuberculosis care in rural China

More information:
Kwan A, Daniels B, Saria V, Satyanarayana S, Subbaraman R, McDowell A, et al. (2018) Variations in the quality of tuberculosis care in urban India: A cross-sectional, standardized patient study in two cities. PLoS Med 15(9): e1002653. doi.org/10.1371/journal.pmed.1002653

Journal reference:
PLoS Medicine

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