Breaking News
May 3, 2019 - Vaping and Smoking May Signal Greater Motivation to Quit
May 3, 2019 - Dementia looks different in brains of Hispanics
May 3, 2019 - Short-Staffed Nursing Homes See Drop In Medicare Ratings
May 3, 2019 - Study of teens with eating disorders explores how substance users differ from non-substance users
May 3, 2019 - Scientists develop new video game that may help in the study of Alzheimer’s
May 3, 2019 - Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium
May 3, 2019 - Cornell University study uncovers relationship between starch digestion gene and gut bacteria
May 3, 2019 - How to Safely Use Glucose Meters and Test Strips for Diabetes
May 3, 2019 - Anti-inflammatory drugs ineffective for prevention of Alzheimer’s disease
May 3, 2019 - Study tracks Pennsylvania’s oil and gas waste-disposal practices
May 3, 2019 - Creating a better radiation diagnostic test for astronauts
May 3, 2019 - Vegans are often deficient in these four nutrients
May 3, 2019 - PPDC announces seed grants to develop medical devices for children
May 3, 2019 - Study maps out the frequency and impact of water polo head injuries
May 3, 2019 - Research on Reddit identifies risks associated with unproven treatments for opioid addiction
May 3, 2019 - Good smells may help ease tobacco cravings
May 3, 2019 - Medical financial hardship found to be very common among people in the United States
May 3, 2019 - Researchers develop multimodal system for personalized post-stroke rehabilitation
May 3, 2019 - Study shows significant mortality benefit with CABG over percutaneous coronary intervention
May 3, 2019 - Will gene-editing of human embryos ever be justifiable?
May 3, 2019 - FDA Approves Dengvaxia (dengue vaccine) for the Prevention of Dengue Disease in Endemic Regions
May 3, 2019 - Why Tonsillitis Keeps Coming Back
May 3, 2019 - Fighting the opioid epidemic with data
May 3, 2019 - Maggot sausages may soon be a reality
May 3, 2019 - Deletion of ATDC gene prevents development of pancreatic cancer in mice
May 2, 2019 - Targeted Therapy Promising for Rare Hematologic Cancer
May 2, 2019 - Alzheimer’s disease is a ‘double-prion disorder,’ study shows
May 2, 2019 - Reservoir bugs: How one bacterial menace makes its home in the human stomach
May 2, 2019 - Clinical, Admin Staff From Cardiology Get Sneak Peek at Epic
May 2, 2019 - Depression increases hospital use and mortality in children
May 2, 2019 - Vicon and NOC support CURE International to create first gait lab in Ethiopia
May 2, 2019 - Researchers use 3D printer to make paper organs
May 2, 2019 - Viral infection in utero associated with behavioral abnormalities in offspring
May 2, 2019 - U.S. Teen Opioid Deaths Soaring
May 2, 2019 - Opioid distribution data should be public
May 2, 2019 - In the Spotlight: “I’m learning every single day”
May 2, 2019 - 2019 Schaefer Scholars Announced
May 2, 2019 - Podcast: KHN’s ‘What The Health?’ Bye-Bye, ACA, And Hello ‘Medicare-For-All’?
May 2, 2019 - Study describes new viral molecular evasion mechanism used by cytomegalovirus
May 2, 2019 - SLU study suggests a more equitable way for Medicare reimbursement
May 2, 2019 - Scientists discover first gene involved in lower urinary tract obstruction
May 2, 2019 - Researchers identify 34 genes associated with increased risk of ovarian cancer
May 2, 2019 - Many low-income infants receive formula in the first few days of life, finds study
May 2, 2019 - Global study finds high success rate for hip and knee replacements
May 2, 2019 - Taking depression seriously: What is it?
May 2, 2019 - With Head Injuries Mounting, Will Cities Put Their Feet Down On E-Scooters?
May 2, 2019 - Scientists develop small fluorophores for tracking metabolites in living cells
May 2, 2019 - Study casts new light into how mothers’ and babies’ genes influence birth weight
May 2, 2019 - Researchers uncover new brain mechanisms regulating body weight
May 2, 2019 - Organ-on-chip systems offered to Asia-Pacific regions by Sydney’s AXT
May 2, 2019 - Adoption of new rules drops readmission penalties against safety net hospitals
May 2, 2019 - Kids and teens who consume zero-calorie sweetened beverages do not save calories
May 2, 2019 - Improved procedure for cancer-related erectile dysfunction
May 2, 2019 - Hormone may improve social behavior in autism
May 2, 2019 - Alzheimer’s disease may be caused by infectious proteins called prions
May 2, 2019 - Even Doctors Can’t Navigate Our ‘Broken Health Care System’
May 2, 2019 - Study looks at the impact on criminal persistence of head injuries
May 2, 2019 - Honey ‘as high in sugars as table sugar’
May 2, 2019 - Innovations to U.S. food system could help consumers in choosing healthy foods
May 2, 2019 - FDA Approves Mavyret (glecaprevir and pibrentasvir) as First Treatment for All Genotypes of Hepatitis C in Pediatric Patients
May 2, 2019 - Women underreport prevalence and intensity of their own snoring
May 2, 2019 - Concussion summit focuses on science behind brain injury
May 2, 2019 - Booker’s Argument For Environmental Justice Stays Within The Lines
May 2, 2019 - Cornell research explains increased metastatic cancer risk in diabetics
May 2, 2019 - Mount Sinai study provides fresh insights into cellular pathways that cause cancer
May 2, 2019 - Researchers to study link between prenatal pesticide exposures and childhood ADHD
May 2, 2019 - CoGEN Congress 2019: Speakers’ overviews
May 2, 2019 - A new strategy for managing diabetic macular edema in people with good vision
May 2, 2019 - Sagent Pharmaceuticals Issues Voluntary Nationwide Recall of Ketorolac Tromethamine Injection, USP, 60mg/2mL (30mg per mL) Due to Lack of Sterility Assurance
May 2, 2019 - Screen time associated with behavioral problems in preschoolers
May 2, 2019 - Hormone reduces social impairment in kids with autism | News Center
May 2, 2019 - Researchers synthesize peroxidase-mimicking nanozyme with low cost and superior catalytic activity
May 2, 2019 - Study results of a potential drug to treat Type 2 diabetes in children announced
May 2, 2019 - Multigene test helps doctors to make effective treatment decisions for breast cancer patients
May 2, 2019 - UNC School of Medicine initiative providing unique care to dementia patients
May 2, 2019 - Nestlé Health Science and VHP join forces to launch innovative COPES program for cancer patients
May 2, 2019 - Study examines how our brain generates consciousness and loses it during anesthesia
May 2, 2019 - Transition Support Program May Aid Young Adults With Type 1 Diabetes
May 2, 2019 - Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death
May 2, 2019 - Research reveals complexity of how we make decisions
Dementia prevention trial participants are motivated by altruism, study suggests

Dementia prevention trial participants are motivated by altruism, study suggests

Researchers at University of California San Diego School of Medicine, with collaborators across the country, report that people who participate in dementia prevention trials are primarily motivated by altruism and pleased to help.

The findings are published in the October 5 issue of Alzheimer’s & Dementia.

“For the most part, people appeared satisfied with their experience in a clinical trial,” said first author Mary Sano, PhD, professor of psychiatry and director of the Alzheimer’s Disease Research Center at Mount Sinai School of Medicine in New York City. “A big takeaway is how altruism and giving back are important to participants. We were also intrigued by the desire for increased social interactions.”

The study surveyed 422 non-demented participants, age 75 and older, in the Home-Based Assessment (HBA) study at 27 sites across the country. The HBA study — a four-year, longitudinal study using novel technologies to determine the feasibility of assessing cognitively normal older adults in their own homes — was coordinated by the Alzheimer’s Disease Cooperative Study (ADCS), an initiative of the National Institute on Aging based at UC San Diego School of Medicine.

Almost 6 million Americans are currently living with Alzheimer’s disease (AD), according to the Alzheimer’s Association, with an American developing the disease every 65 seconds. By 2050, the number of persons with AD is projected to rise to nearly 14 million, making the need for research critical.

Yet little is known about the factors affecting the motivation and satisfaction of participants in dementia prevention trials, say experts. Beyond a motivation to help, the new study was an attempt to determine how future clinical trials might be made more attractive and effective. The HBA study involved various levels of technology, such as mail-in questionnaires, live telephone interviews, automated telephone calls with interactive voice response and an internet-connected, home-sited computer kiosk with responses captured via automated speech recognition.

Researchers found that trial participants preferred staff-administered assessments more than automated technologies; greater opportunity to challenge and improve their own mental function (such as a wider variety of activities during testing); and increased interaction with both study staff and other, older adults. They also sought more personal feedback from researchers as the trial progressed.

Sano said it wasn’t surprising that participants became bored with repetitive tasks and frustrated by inevitable equipment glitches.

“It’s important to understand because it’s common for new trials to have more technology and less human interaction,” she said. “While advanced technology is clearly essential, we also must remember that people want to feel valued for their own ideas and personalities.”

Co-author Jeffrey Kaye, MD, professor of neurology at Oregon Health and Science University and director of both the Layton Aging and Alzheimer’s Disease Center and the Oregon Center for Aging and Technology, suggested technology should be used with participant comfort in mind.

“To maximize the advantages that technologies can bring to clinical trials, it is important to ensure that devices or interactions with technology are integrated into participants’ everyday lives. Ideally, the technology works in the background and is as unobtrusive as possible. If there are needed interactions, these must be engaging and minimally burdensome, especially when studies may be conducted over many years.”

Senior author Howard Feldman, MD, professor of neurosciences at UC San Diego School of Medicine, and clinical neurologist and director of the ADCS said the findings should inform and improve future study design.

“By listening to the concerns and suggestions of our participants, we build better, more effective studies in the future,” he said. “It’s good to know that participants are feeling the spirit of altruism in this work, as we are essentially relying on successful expansion of this community effort to address the ever increasing size and challenges of Alzheimer’s disease.

“It is incumbent on us to listen and plan accordingly. It is also important to note, and not to underestimate, the human element described in this research. Direct human interaction seems to be an important contributor to participant engagement and retention. It is a reminder that human contact provides a benefit to these studies, supporting participants in a way that technology cannot.”​​

Source:

https://ucsdnews.ucsd.edu/pressrelease/participants_in_dementia_prevention_research_motivated_by_altruism

About author

Related Articles