Breaking News
March 18, 2019 - Taking painkillers during pregnancy is not responsible for asthma risk in children, study shows
March 18, 2019 - Prediagnosis Psychiatric Care Linked to Worse Cancer Mortality
March 18, 2019 - Paris hospital halts stool study after donor deluge
March 18, 2019 - Partial oral antibiotic therapy shows efficacy and safety in patients with infectious endocarditis
March 18, 2019 - Olympus improves access to science education through BioBus collaboration
March 18, 2019 - Depression screening does not improve quality of life in heart attack patients
March 18, 2019 - Echocardiography may aid in patient selection for TMVR
March 18, 2019 - Are ‘Inactive’ Ingredients in Your Drugs Really So Harmless?
March 18, 2019 - Scientists tackle rare retinal disease in unique research project
March 18, 2019 - Death By A Thousand Clicks
March 18, 2019 - Absorbable, antibiotic-eluting envelope can reduce rate of cardiac device infections
March 18, 2019 - Hormonal treatment associated with depression in men with prostate cancer
March 18, 2019 - Porvair Sciences launches reinforced 96-well deep round microplate
March 18, 2019 - Simplified catheter ablation could slash waiting lists for atrial fibrillation patients
March 18, 2019 - BFR therapy as part of rehabilitation following ACL surgery may slow bone loss
March 18, 2019 - A human model to test implants for cataract surgery
March 18, 2019 - New risk adjustment model could reduce financial penalty for safety net hospitals
March 18, 2019 - NHS cancer patients’ wait to start treatment worrying
March 18, 2019 - Inventiva Announces Results from Phase IIb Clinical Trial with Lanifibranor in Systemic Sclerosis
March 18, 2019 - Cologuard
March 18, 2019 - Researchers find evidence of prenatal environment tuning genomic imprinting
March 18, 2019 - Dolomite Bio launches novel Nadia product family for single-cell research
March 18, 2019 - Intellipharmaceutics Announces Resubmission of New Drug Application to the U.S. FDA for its Oxycodone ER
March 18, 2019 - Excessive gestational weight gain tied to maternal morbidity
March 18, 2019 - RCEM issues position statement on metrics to supplement four-hour standard target
March 17, 2019 - Noncontrast Brain MRI Effective for Monitoring Multiple Sclerosis
March 17, 2019 - Brain region plays key role in regulation of parenting behavior, study finds
March 17, 2019 - Natural speed limit on DNA replication sets pace for life’s first steps
March 17, 2019 - New research reveals overlooked impact of herbicide glyphosate on the environment
March 17, 2019 - Molecular patterns could help predict relapse risk in breast cancer patients
March 17, 2019 - Study confirms sensitivity of microbiological cultures for detecting cholera
March 17, 2019 - Scientists Spot Clues to Predicting Breast Cancer’s Return
March 17, 2019 - Scientists identify gene that keeps PTSD-like behavior at bay in female mice
March 17, 2019 - New method would allow doctors to detect earliest stages of cancers in the lymph nodes
March 17, 2019 - Cholesterol protein discovery raises hope for smarter drugs
March 17, 2019 - New insect medium delivers high viable cell density growth and protein yield
March 17, 2019 - Opioid crisis brings concerns about heart dangers
March 17, 2019 - Resistance Training May Prevent Type 2 Diabetes Progression
March 17, 2019 - Bioluminescence sensors make new approaches to drug discovery possible
March 17, 2019 - New FDA Rules Aim to Keep Kids From Flavored E-Cigarettes
March 17, 2019 - Vitamin B3 analogue boosts production of blood cells
March 17, 2019 - Government cuts to stop smoking services have detrimental impact on public health
March 17, 2019 - Common tool to assess potential adoptive parents lags behind societal changes
March 17, 2019 - Patients’ own cells could be the key to treating Crohn’s disease
March 17, 2019 - Diagnostic delays common in inflammatory bowel disease
March 17, 2019 - Study uncovers dramatic differences in the brains of Hispanics with dementia
March 17, 2019 - Study describes epigenetic loss that changes how cells obtain energy from cancer
March 16, 2019 - Active Bathing in Non-ICU Setting Does Not Cut Infections
March 16, 2019 - How the immune system maintains a healthy gut microbiota
March 16, 2019 - Bacteria ‘trap’ could help in the fight against antimicrobial resistance
March 16, 2019 - Hospital work environment associated with all EHR usability outcomes
March 16, 2019 - Study unravels mystery behind how the brain encodes time when forming long-term memories
March 16, 2019 - Light physical activity may lower risk of cardiovascular disease in older women
March 16, 2019 - USP15 enzyme could potentially lead to new treatments for breast, pancreatic cancer
March 16, 2019 - After Chinese Infant Gene-Editing Scandal, U.S. Health Officials Join Call for a Ban
March 16, 2019 - PACS1 syndrome – Genetics Home Reference
March 16, 2019 - Researchers discover an unexpected organization of antimicrobial molecules that amplifies immune response
March 16, 2019 - With New Study, Era of Open-Heart Surgery for Aortic Stenosis May be Ending
March 16, 2019 - Dolomite Bio introduces high throughput sNuc-Seq protocol for its Nadia Instrument
March 16, 2019 - New course prepares materials scientists for biomedical testing
March 16, 2019 - Finding clues to a functional HIV cure
March 16, 2019 - People with chronic periodontitis have higher risk for dementia
March 16, 2019 - Few heart care recommendations are based on rigorous study
March 16, 2019 - Colorectal cancer diagnosed at early age is distinct from that in older patients
March 16, 2019 - Researchers use MRI and AI techniques at birth to predict cognitive development at age 2
March 16, 2019 - Discarding information from the brain linked to more mental effort, finds study
March 16, 2019 - OTA International supplement provides current snapshot and forward look at global trauma systems
March 16, 2019 - NIH trial to track outcomes of liver transplantation from HIV+ donors to HIV+ recipients
March 16, 2019 - Apple Heart Study shows how wearable technology can help detect heart problem
March 16, 2019 - Researchers determine factors that cause stress development in the human body
March 16, 2019 - Elderly Men Undertreated for Osteoporosis
March 16, 2019 - People with chronic pain are coping with the help of Pinterest, new study reveals
March 16, 2019 - New study could reveal the complex interaction between languages and human beings who use them
March 16, 2019 - Tufts engineers develop new tool to identify metabolic signatures linked to disease
March 16, 2019 - New proteomics-based test could aid in early detection of ovarian cancer
March 16, 2019 - New research opens possibility of using sperm taken from testicles to overcome infertility
March 16, 2019 - Scientists find new proof that narcolepsy is an autoimmune disease
March 16, 2019 - FDA OKs a New Generic of the Blood Pressure Drug Valsartan to Ease Shortage Due to Recalls
March 16, 2019 - Eliminating smoking and obesity could affect racial health disparities
March 16, 2019 - Wearable tracking device achieves higher accuracy in position tracking using thermal sensors
Study shows cigarillo flavors enhanced by high-intensity sweeteners

Study shows cigarillo flavors enhanced by high-intensity sweeteners

image_pdfDownload PDFimage_print
Credit: stock.adobe.com

In a new study, Yale researchers found that popular brands of cigarillos are flavored with high-intensity sweeteners, potentially reducing the aversive sensation of smoking and making cigarillos more palatable. The concern is that these sweeteners encourage young people to smoke cigarillos.

Cigarillos are small cigars that have become increasingly popular in recent years. Only slightly larger than cigarettes, cigarillo flavors aren’t subject to the same restrictions in the U.S. as cigarettes. Adding any flavors other than menthol to cigarettes is not allowed. In contrast, cigarillos come in a wide variety of flavors—one of the reasons the products are especially popular among youth.

The study, published today in the Journal of the American Medical Association (JAMA), found that high-intensity sweeteners—chemicals such as sucralose, which can be hundreds of times sweeter than sugar—were present not only in cigarillos labeled as having “sweet” flavor, but also in cigarillos with “classic” cigar and fruity flavors such as “grape.” The researchers analyzed the six most popular brands in the U.S., which account for 90% of the national cigarillo market. For each brand, they tested at least one product that featured a “sweet” flavor, a “classic” flavor, and where available, a fruity flavor such as grape. The project was a collaboration between the lab of Julie Zimmerman, professor of chemical and environmental engineering, and the Yale Tobacco Center of Regulatory Science (TCORS) in the department of psychiatry, with support by Sven Jordt at Duke University.

Of the 31 cigarillo wrappers examined, 29 had high-intensity sweeteners in all tested flavors. Using table sugar as the standard of sweetness, the researchers found that 74 percent of the analyzed cigarillo wrappers were sweeter than a sugar-free candy. Sweeteners were found predominantly on the mouth end of the cigarillo, creating an easy route to the user’s taste buds.

“Once these compounds reach the tongue and thereby the taste buds, they create a sweet, pleasant, and possibly rewarding taste that can mask the bitter taste of nicotine and tobacco,” said first author Hanno Erythropel, a postdoctoral associate in Zimmerman’s lab and a trainee in TCORS.

The concern, said co-author Stephanie O’Malley, is that flavors in tobacco products not only encourage young people to start using these products, but to continue using them by reducing the harsh, bitter taste that often keeps one-time users from smoking again.

“Nicotine is addicting, but you have to expose yourself repeatedly to become addicted,” said O’Malley, professor of psychiatry. “The initial use of these products can be aversive, and things like sweeteners can make them less so.”

The Food and Drug Administration is considering expanding the current ban on flavors in cigarettes to cigarillos and other cigars, and similar efforts exist in several states and cities. The researchers note, though, that such regulations currently extend only to flavors and not high-intensity sweeteners. The researchers say they hope the study’s findings will inform regulatory policies with the goal of preventing Americans from becoming addicted to nicotine.


Explore further:
Cigarillo packaging can influence product perception, study finds

More information:
Presence of High-Intensity Sweeteners in Popular Cigarillos of Varying Flavor Profiles JAMA. DOI: 10.1001/jama.2018.11187

Journal reference:
Journal of the American Medical Association

Provided by:
Yale University

About author

Related Articles