Breaking News
March 22, 2019 - Less invasive valve replacement can be safe and effective alternative for healthier patients
March 22, 2019 - Aphasia research reveals new, complex interactions between thought and language
March 22, 2019 - Artificial neural networks can predict how different areas in the brain respond to words
March 22, 2019 - Age-related changes to gut microbiome have adverse impact on vascular health, study shows
March 22, 2019 - Isolated seniors chat online to prevent cognitive decline
March 22, 2019 - Karyopharm Announces FDA Extension of Review Period for Selinexor New Drug Application
March 22, 2019 - Eruptive xanthomatosis
March 22, 2019 - Cause of vascular disease in kidney failure reversed in animal model
March 22, 2019 - Researchers discover possible new therapeutic strategy for pancreatic cancer
March 22, 2019 - Ebola spreads to second largest city in DRC
March 22, 2019 - Perivascular spaces contribute to worse cognitive health in older adults
March 22, 2019 - Adolescent daily users more likely to obtain electronic cigarettes from commercial sources
March 22, 2019 - FDA Approves Genentech’s Tecentriq in Combination With Chemotherapy for the Initial Treatment of Adults With Extensive-Stage Small Cell Lung Cancer
March 22, 2019 - Diabetes myths and facts: MedlinePlus Medical Encyclopedia
March 22, 2019 - TGen and ABL pursue global rollout of advanced TB test
March 22, 2019 - Traffic light labels influence people to choose healthier and more sustainable meals
March 22, 2019 - Alzheimer’s patients using antiepileptic drugs have twice the risk of pneumonia, study shows
March 22, 2019 - Skin diseases may be more prevalent than previously thought
March 22, 2019 - Overall rates of death from breast cancer are falling across the EU
March 22, 2019 - Novel plasmid could hold key to control of mosquito-borne illness
March 22, 2019 - Female Emergency Physicians Paid Less Than Males
March 22, 2019 - Estimated average glucose (eAG): MedlinePlus Medical Encyclopedia
March 22, 2019 - Experimental drug could be new option for type 2 diabetes
March 22, 2019 - Five Things To Know About The Electronic Health Records Mess
March 22, 2019 - TMJ disorders could be treated with tissue-engineered implants after successful animal study
March 22, 2019 - Team-based approach is key to successful care of pregnant women with heart failure
March 22, 2019 - Study identifies gene variant associated with accelerated cellular aging
March 21, 2019 - Salk scientists show how background noise from neurons can interrupt focused attention
March 21, 2019 - New class of drugs could help treat patients diagnosed with ovarian cancer
March 21, 2019 - Tecentriq Approved for Small Cell Lung Cancer
March 21, 2019 - Adipocyte glucocorticoid receptors play a role in developing steroid diabetes
March 21, 2019 - Climate change can affect nutrient content of crops, harming human health
March 21, 2019 - Podcast: KHN’s ‘What The Health’ Surprise! Fixing Surprise Medical Bills Is Harder Than it Looks
March 21, 2019 - Chemistry researchers patent new method for making anti-leukemia compounds
March 21, 2019 - UIC scientists identify hidden proteins in bacteria
March 21, 2019 - New Australian drug trial achieves remarkable results in patients with acute myeloid leukemia
March 21, 2019 - Females live longer when they have help raising offspring
March 21, 2019 - How did orthodontists sell orthodontics?
March 21, 2019 - In the Spotlight: From dietitian to physician assistant student
March 21, 2019 - The CRISPR Revolution: What You Need to Know
March 21, 2019 - FDA Chief Calls For Stricter Scrutiny Of Electronic Health Records
March 21, 2019 - Combined glucocorticoid and antioxidant therapy could benefit premature babies
March 21, 2019 - Low levels of certain eye proteins could serve as predictor for Alzheimer’s
March 21, 2019 - Post-traumatic holocaust survivors transmit negative views on aging to offspring
March 21, 2019 - City of Hope receives $7.5 million in grant awards to study cutaneous T cell lymphoma
March 21, 2019 - New video game-led training device helps stroke survivors regain arm mobility
March 21, 2019 - Compounds in coffee could slow prostate cancer growth
March 21, 2019 - New mobile DNA element in Wolbachia may contribute to improved disease control strategies
March 21, 2019 - Phase 2 Clinical Trial of Bermekimab Shows Potential New Standard of Care for Treatment of Hidradenitis Suppurativa, Including Significant Pain Reduction without Antibiotics
March 21, 2019 - More than one-third of patients risk major bleeding by doubling up on blood thinners
March 21, 2019 - A skeptical look at popular diets: Thumbs up for Mediterranean
March 21, 2019 - PTSD After Cardiac Arrest Predicts More Heart Trouble
March 21, 2019 - Role of immunological imprinting in elicitation of new antibodies
March 21, 2019 - Breast cancer relapse predictor tool may soon be a reality
March 21, 2019 - New computer program developed by TGen lights up cancer-causing genetic mutations
March 21, 2019 - FDA warns two breast implant makers for failure to comply with post-approval study requirements
March 21, 2019 - Butler Hospital receives COBRE grant to enhance research on neuropsychiatric illnesses
March 21, 2019 - Majority of osteoporosis clinical practice guidelines ignore patients’ voices
March 21, 2019 - Generic messages don’t help patients to lose weight
March 21, 2019 - Eisai and Imbrium Therapeutics Announce U.S. FDA Filing Acceptance of New Drug Application for Lemborexant for the Treatment of Insomnia
March 21, 2019 - Two-drug combos using popular calcium channel blocker show superiority in lowering BP
March 21, 2019 - Q BioMed and Mannin Research collaborate with McMaster University to develop GDF15 biomarker glaucoma diagnostic kit
March 21, 2019 - First-in-human pilot study shows positive results for ‘bacteria-phobic’ catheter
March 21, 2019 - Itamar Medical launches next-generation WatchPAT system for home sleep apnea testing
March 21, 2019 - Study estimates health and economic impacts of healthy food prescriptions
March 21, 2019 - Detecting fungal disease in crops with multispectral imaging system
March 21, 2019 - MIT announces creation of the Alana Down Syndrome Center
March 21, 2019 - Next-generation LVAD device clinically superior, safer for heart failure patients
March 21, 2019 - Allergan Announces FDA Approval of Avycaz (ceftazidime and avibactam) for Pediatric Patients
March 21, 2019 - Mutations in noncoding genes could play big role in regulating cancer, study finds
March 21, 2019 - A medical student’s thoughts on Match Day
March 21, 2019 - Are eggs good or bad for you?
March 21, 2019 - New analysis reveals precision oncology insights for colorectal cancer
March 21, 2019 - Pollutants appear to weaken immune system and increase pathogen virulence
March 21, 2019 - Researchers develop and validate scale for rating severity of mononucleosis
March 21, 2019 - Scientists identify generation of key immune response in mice on introducing solid food
March 21, 2019 - New nanomaterial could restore internal structure of damaged bones
March 21, 2019 - Selective destruction of prostate tumor as effective as complete prostate removal
March 21, 2019 - 2011 to 2015 Saw Increase in Psychiatric ED Visits for Youth
March 21, 2019 - Tapeworm drug targets common vulnerability in tumor cells
Innovative supportive care model tackles burdensome symptoms, challenges of dementia

Innovative supportive care model tackles burdensome symptoms, challenges of dementia

image_pdfDownload PDFimage_print

Individuals with dementia often experience burdensome symptoms such as agitation, aggression, anxiety and pain, but have difficulty with comprehension and communication, making it challenging for healthcare providers to provide appropriate treatment.

With the goals of improving care for symptom management and other burdens of dementia as well as empowering their family caregivers, researchers from the Regenstrief Institute and Indiana University Center for Aging Research are integrating state of the art dementia care with palliative care through an innovative supportive care model they have named IN-PEACE. The initiative is funded by a new $3.5 million grant from the National Institute on Aging.

“Dementia has become one of the leading causes of death in the U.S., overtaking many of the chronic conditions that people typically think of as leading causes of death,” said Regenstrief Institute and IU Center for Aging Research investigator Greg Sachs, M.D., who designed and leads IN-PEACE. “We believe IN-PEACE will reshape how care is provided to people with dementia and their families, especially in the later stages of the illness.”

IN-PEACE is the first randomized controlled trial that simultaneously targets patient symptoms, caregiver mood and distress as well as the reduction of burdensome and potentially unnecessary treatments for community dwellers with dementia. IN-PEACE provides support by nurses and social workers for both decisionmaking and transitions in care.

“Neuropsychiatric symptoms like agitation, aggression, anxiety, and repetitive behaviors are too often treated with medications which produce greater adverse effects than benefits for individuals with dementia,” said Dr. Sachs. “We have designed IN-PEACE to focus on these neuropsychiatric symptoms, as well as to recognize and sort out if someone is having pain and to treat these burdens of dementia earlier and more effectively.”

“As we treat discomfort and other significant hardships in the individual with dementia, we are working with family caregivers to lower their stress and hopefully see less depression in these spouses, daughters, daughters-in-law and others who are bearing such a tremendous burden.” Dr. Sachs, an internationally respected leader in geriatrics and palliative care, directs IU School of Medicine’s Division of General Internal Medicine and Geriatrics.

IN-PEACE is an acronym for Indiana Palliative Excellence in Alzheimer’s Care Efforts. Palliative care, which focuses on providing relief from the symptoms and stress of a serious illness by understanding and meeting a patient’s preferences and goals, can be extended to patients with any serious illness. Palliative care, though frequently provided to cancer patients, is far less often offered to patients with dementia to help them and their families navigate the course of this severe, and often lengthy, illness.

IN-PEACE will enroll 200 patients from throughout central Indiana with Alzheimer’s disease and other dementias including cognitive impairment from Parkinson’s disease and stroke in addition to their 200 caregivers. Each patient-caregiver pair will be randomized to usual or enhanced care. Outcomes of the two groups will be compared.

Usual care will consist of the primary care and any specialty care that the dementia patient and family member is already receiving in their community. Enhanced care recipients will receive usual care plus an additional layer of support spearheaded by a nurse or social worker who will maintain regular in-person and phone contact with the patient and caregiver, conduct routine assessments of anxiety, pain and other symptoms and intervene rapidly rather than waiting for the individual to come to his or her physician’s office or to go to a hospital emergency department.

Although the onset of cognitive impairment can occur at any age, risk for dementia increases with age. The U.S. is getting older, and the Census Bureau reports that in 2015, nearly 15 percent of the U.S. population was 65 or older.

In addition to Dr. Sachs, IN-PEACE co-investigators include Alexia Torke, M.D., and Kurt Kroenke, M.D., both of the Regenstrief Institute and IU School of Medicine; Mary Guerriero Austrom, Ph.D. of the Indiana Alzheimer Disease Center and IU School of Medicine; Sujuan Gao, Ph.D. of IU School of Medicine and Susan Hickman, Ph.D. of IU School of Nursing, Dr. Sachs describes them as an all-star team with expertise in palliative care symptom management, family caregiving and biostatistics.

IN-PEACE will enroll its first patients and caregivers in January 2019. Study participants will be referred to IN-PEACE by the Central Indiana physicians the patient routinely sees.

Source:

https://www.regenstrief.org/article/in-peace-tackles-symptoms-challenges-of-dementia/

Tagged with:

About author

Related Articles