Breaking News
March 26, 2019 - DermBiont Begins Phase 2 Clinical Trial for Athlete’s Foot with a Live Bacterial Topical Probiotic
March 26, 2019 - Persons with Alzheimer’s disease have a higher risk of head injuries
March 26, 2019 - Mental health issues associated with income inequalities in Indigenous people
March 26, 2019 - Participation in sports linked with fewer depressive symptoms in children
March 26, 2019 - Brain process common to sleep and aging discovered
March 26, 2019 - People under age 50 with hearing loss more likely to misuse alcohol and drugs
March 26, 2019 - People with and without cancer use different dosages of cannabis formulations, study shows
March 26, 2019 - Young people at risk of addiction show differences in key brain region
March 26, 2019 - In virtual exchange, students in California and Lebanon unite to improve refugee health
March 26, 2019 - Trump Administration Changes Course, Asks Court To Strike Down ACA
March 26, 2019 - People with untreated diabetes develop signs of Alzheimer’s disease at a faster rate
March 26, 2019 - Study explains how bright colors evolved and diversified in male guppies
March 26, 2019 - Savings from lower insurance costs of growth hormone drugs not passed on to patients
March 26, 2019 - Study highlights the need to pay more attention on specific nutritional needs of female athletes
March 26, 2019 - Sleep quality varies throughout menstrual cycle in young women
March 26, 2019 - Younger Female Blood Donors Vulnerable to Iron Deficiency
March 26, 2019 - Finding the elusive drinking ‘brake’
March 26, 2019 - Using the Mastermind strategy in brain research
March 26, 2019 - Symptomatic pharmacotherapy of elderly people should be regularly monitored
March 26, 2019 - Synthetic biological logic gate could one day be used to modify cellular function
March 26, 2019 - Damage to anxiety-associated brain region heightens monkeys’ defensive response
March 26, 2019 - Researchers uncover large-scale brain patterns and networks which control sleep
March 26, 2019 - Scientific Symposium at LABVOLUTION focuses on key issues in life sciences
March 26, 2019 - Screen time plus snacking could increase risk for metabolic syndrome in teens
March 26, 2019 - Attention, Seniors: Drink More Water and Head Off Disease
March 26, 2019 - Peptide shows promise for protecting kidneys from nephritis
March 26, 2019 - Causes of diabetes decline or disappear when ‘zombie cells’ are removed, shows study
March 26, 2019 - Scientists identify common genetic variants associated with post-stroke recovery
March 26, 2019 - Study finds link between menopause and changes in body composition
March 26, 2019 - Higher levels of sex hormones in older men related to lower biological age
March 26, 2019 - Research links participation in team sports to larger hippocampal volumes in children
March 26, 2019 - Cerveau announces research collaboration agreement with Eisai for novel tau imaging agent
March 26, 2019 - New technique measures frequency of sounds emitted from biological structures
March 26, 2019 - Removal of ‘zombie cells’ alleviates causes of diabetes in obese mice
March 26, 2019 - Women exposed to deepwater horizon oil spill continue to experience PTSD symptoms
March 26, 2019 - Shaping new treatments for tuberculosis
March 26, 2019 - Understanding genetic interactions holds key to new personalized therapies
March 26, 2019 - Nervous system relies on guidance cues for neuronal axons to reach destinations
March 26, 2019 - Altering gut microbiome may be potential treatment option for PCOS
March 26, 2019 - Moleculin Files with FDA for Expedited Approval Pathway for Annamycin
March 26, 2019 - GPs play pivotal role in ensuring success of new Faster Diagnosis Standard for Cancer
March 26, 2019 - New clues discovered to lung transplant rejection
March 26, 2019 - New study offers insight into development of delusions
March 26, 2019 - Children’s ball pits full of pathogenic microbes
March 26, 2019 - Exploring pathophysiological factors that link sleep problems and Alzheimer’s disease
March 26, 2019 - Walking downhill after meals can reduce bone resorption in postmenopausal women with diabetes
March 26, 2019 - USA LESS Issues Voluntary Nationwide Recall of LEOPARD Miracle Honey Due to Presence of Undeclared Sildenafil
March 26, 2019 - CT scan prior to spine fusion finds almost half of patients had undiagnosed osteoporosis
March 26, 2019 - After 2 Apparent Student Suicides, Parkland Grieves Again
March 25, 2019 - Inherited form of rickets improves more with new injectable medicine than conventional therapy
March 25, 2019 - Trastuzumab Tied to Higher Long-Term Risk for Heart Failure
March 25, 2019 - Personal context directly affects CPAP use
March 25, 2019 - Mosquito tracking key to preventing disease outbreaks
March 25, 2019 - Scientists Detect Hidden Signals from Beneficial Bacteria
March 25, 2019 - Treating women with thyroid antibodies with Levothyroxine do not increase live birth rate
March 25, 2019 - Brain area that only processes spoken, not written words identified
March 25, 2019 - Race and ethnicity influence fracture risk in diabetic patients
March 25, 2019 - Researchers report new regenerative medicine approach for treating osteoarthritis of the knee
March 25, 2019 - Exposure to dim light at night may contribute to spread of breast cancer to bones
March 25, 2019 - Benefits of osteoporosis treatment in postmenopausal women outweigh the perceived risks
March 25, 2019 - Researchers find evidence of Cryptosporidium parasite in Minnesota’s public water systems
March 25, 2019 - Three Clues to Raised Risk of Miscarriage
March 25, 2019 - Structured play helps toddlers self-regulate, altering their life course
March 25, 2019 - Translating horror into justice: Stanford psychiatrist advocates for human rights
March 25, 2019 - HORIBA Medical introduces D-Dimer reagent for Yumizen G hemostasis range
March 25, 2019 - Recurrent pregnancy loss may be caused by sperm DNA damage, finds study
March 25, 2019 - Special Collection tracks development of new diagnostic tests for tuberculosis
March 25, 2019 - Air Force develops genetic test to predict mental performance
March 25, 2019 - To abort or not to abort—making difficult choices alone
March 25, 2019 - Computer vision technology could aid ICU care by spotting movement
March 25, 2019 - IONTAS wins ‘Small Business of the Year’ category at Cambridge News Business Excellence Awards 2019
March 25, 2019 - First postpartum depression drug gets FDA nod
March 25, 2019 - Research Recognition Award will help improve lives of young people with absence epilepsy
March 25, 2019 - Bisphosphonates to treat osteoporosis appears to be beneficial for all women
March 25, 2019 - Time-restricted eating may prove to be a dietary intervention against breast cancer
March 25, 2019 - Researchers develop new augmented reality app to assess spatial memory
March 25, 2019 - Dolomite Bio releases new Drop-seq datasets for single-cell RNA sequencing
March 25, 2019 - Hemoglobin A1c blood test may underestimate prevalence of diabetes
March 25, 2019 - Immune system errors linked to development of childhood leukemia
March 25, 2019 - Eating leafy green vegetables may help maintain muscle strength and mobility
Hyperspectral imaging helps improve patient outcomes after brain tumor surgery

Hyperspectral imaging helps improve patient outcomes after brain tumor surgery

image_pdfDownload PDFimage_print

Advances in real-time hyperspectral imaging gives neurosurgeons new precision when operating on the brain, improving patient outcomes

Identifying healthy from diseased tissue poses a unique problem for cancer surgeons. Even the smallest bits of a tumor left behind during surgery can regrow and spread to other organs, a deadly phenomenon called metastasizing.

To guard against this, surgeons remove a buffer zone of healthy tissue surrounding a tumor. For a skin tumor this is not a major concern, but for brain tumors it becomes a serious problem because every piece of brain tissue is important.

An innovative tool to face the problem is hyperspectral imaging. The technology allows hundreds of wavelengths of light to be seen from beyond the visible spectrum with a very fine spatial resolution. So fine, that for every image pixel a full spectrum of color can be detected.

“It gives you an extra dimension within an image,” explains Ilias Tachtsidis, Associate Professor in Biomedical Engineering at the University College London. “With hyperspectral an image becomes a color map.” And that map can lead the way to removing the damage and leaving the precious healthy tissue intact.

This technique has proven very valuable in the field of medical imaging, says Lise Randeberg, Professor in Biomedical Optics and Photonics at the Norwegian University of Science and Technology. She’s been at the forefront of adapting this technology to medicine since the early 2000s. A colleague working in satellite imaging introduced her to hyperspectral imaging and the possibility of finding what she calls “the spectral fingerprints of biological compounds and tissue types.”

Depending on the physical property of the objects being imaged a unique spectral fingerprint is revealed. This data is what produces the color map but the challenge, Tachtsidis explains, is “identifying what this color map tells you about healthy and unhealthy tissue.”

This is what Gustavo Marrero Callicó, Professor of Applied Microelectronics at the University of Las Palmas de Gran Canaria, and the HELiCoiD project are attempting to do. “They, being the neurosurgeons, had a problem and we had a technology,” says Callicó.

Supported by the EU Future and emerging Technologies (FET) program, the researchers took hyperspectral cameras, adapted them to the demands of the neurosurgery suite and began building a database of images, confirming they could discriminate between tumor and normal brain.

But every patient’s tumor and brain produce a unique spectral fingerprint, and so the first algorithms to make usable images took a half hour. To deal with this Callicó turned to techniques found in supercomputing and machine learning. “We made special emphasis on the parallelization of the algorithm,” he says. “Now the total time is around six seconds.”

Now they are equipped to provide neurosurgeons with a tool to operate on the slimmest of margins in real-time. The next goal is refining the database to make it general enough to detect cancers in many situations.

Callicó also sees a future whereby most diagnostics can be aided by this technique, reducing the need for biopsies, fluorescent dyes or tissue staining.

“I think hyperspectral medicine is here to stay,” says Randeberg. “It could speed up medical diagnostics substantially, help decision making and improve the quality of diagnostics.”

Tachtsidis also believes that these techniques “have a very positive future.” He is especially interested in the potential biomarkers that may be discovered using hyperspectral imaging.

Source:

http://www.fetfx.eu/story/saving-lives-cancer-surgery-separating-good-bad/ ​

About author

Related Articles