Breaking News
March 22, 2019 - Researchers develop new tool for imaging large groups of neurons in living animals
March 22, 2019 - Certain bacteria and immune factors in vagina may cause or protect against preterm birth
March 22, 2019 - Novel breath test could pave new way to non-invasively measure gut health
March 22, 2019 - Pharmaceutical and personal care products may result in new contaminants in waterways
March 22, 2019 - ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib
March 22, 2019 - Wiedemann-Rautenstrauch syndrome – Genetics Home Reference
March 22, 2019 - Health insurance is not assurance of healthcare
March 22, 2019 - Supporting “curiosity-driven research” at the Discovery Innovation Awards
March 22, 2019 - Must-Reads Of The Week (Some Flying Below The Radar)
March 22, 2019 - Newly engineered nanoscale protein micelles can be tracked by MRI
March 22, 2019 - Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD
March 22, 2019 - Early discharge does not increase readmission risk for patients after lung surgery
March 22, 2019 - Creating diverse pool of trained scientists to address Alzheimer’s research needs
March 22, 2019 - Study shows ACA’s positive impact on healthcare affordability and access for women
March 22, 2019 - New combination treatment shows promise for common brain tumor in children
March 22, 2019 - Virginia Tech Helmet Lab releases first youth-specific football helmet ratings
March 22, 2019 - New algae-based treatment could reduce need for limb amputation
March 22, 2019 - Stroke risk reduces in both black and white older Medicare beneficiaries, study reports
March 22, 2019 - City of Hope exhibits current studies and data on cancer therapies at AACR
March 22, 2019 - New study identifies CD40 molecule as key entry point for dangerous bacteria
March 22, 2019 - Health Tip: Six Steps to a Healthier Life
March 22, 2019 - even a little activity helps you live longer
March 22, 2019 - Many individuals recovering from addiction continue to suffer from chronic physical disease
March 22, 2019 - New drugs on PBS for Parkinson’s, MND and Cutaneous T cell lymphoma
March 22, 2019 - Saving energy also saves lives, UW-Madison study says
March 22, 2019 - Former inmates who receive social support have better mental health, study finds
March 22, 2019 - Nanofibrous membrane could enhance periodontal tissue regeneration
March 22, 2019 - Anti-vaxxer Italian leader down with chickenpox
March 22, 2019 - Servier collaborates with Harvard researchers to fight metabolic diseases
March 22, 2019 - National Eating Disorders Association
March 22, 2019 - Pumping up red blood cell production
March 22, 2019 - Excessive phosphate fertilizer may hurt plants by altering microbial composition in soil
March 22, 2019 - Medical marijuana laws could be improving older Americans’ health, study suggests
March 22, 2019 - Study indicates the benefits of stopping aspirin in heart attack patients
March 22, 2019 - Deep brain stimulation offers significant relief for patients with treatment-resistant depression
March 22, 2019 - Mental health problems in young adults on the rise
March 22, 2019 - Innovative membrane offers a viable solution for periodontitis
March 22, 2019 - The FDA Grants Rare Pediatric Disease Designation to Odiparcil for the Treatment of MPS VI
March 22, 2019 - insulin therapy: MedlinePlus Medical Encyclopedia
March 22, 2019 - Guidelines on the use of genetic testing in psychiatry
March 22, 2019 - Aspiring Doctors Seek Advanced Training In Addiction Medicine
March 22, 2019 - A change in focus could enable the development of new treatments for Alzheimer’s disease
March 22, 2019 - A new way to visualize the immune cell “landscape” of bowel cancer tumors
March 22, 2019 - Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia
March 22, 2019 - Ludwig scientists to share advances in cancer research at AACR Annual Meeting 2019
March 22, 2019 - Less invasive valve replacement can be safe and effective alternative for healthier patients
March 22, 2019 - Aphasia research reveals new, complex interactions between thought and language
March 22, 2019 - Artificial neural networks can predict how different areas in the brain respond to words
March 22, 2019 - Age-related changes to gut microbiome have adverse impact on vascular health, study shows
March 22, 2019 - Study provides new insight into blood cell and immune cell production
March 22, 2019 - Isolated seniors chat online to prevent cognitive decline
March 22, 2019 - Repurposing drugs to outsmart cancers
March 22, 2019 - Naltrexone implant more effective in reducing relapses in HIV patients with opioid addiction
March 22, 2019 - The Brain Institute wins $7.04 million grant to investigate ‘neurophilosphy of free will’
March 22, 2019 - Karyopharm Announces FDA Extension of Review Period for Selinexor New Drug Application
March 22, 2019 - Eruptive xanthomatosis
March 22, 2019 - Cause of vascular disease in kidney failure reversed in animal model
March 22, 2019 - Researchers discover possible new therapeutic strategy for pancreatic cancer
March 22, 2019 - Ebola spreads to second largest city in DRC
March 22, 2019 - Perivascular spaces contribute to worse cognitive health in older adults
March 22, 2019 - Adolescent daily users more likely to obtain electronic cigarettes from commercial sources
March 22, 2019 - FDA Approves Genentech’s Tecentriq in Combination With Chemotherapy for the Initial Treatment of Adults With Extensive-Stage Small Cell Lung Cancer
March 22, 2019 - Diabetes myths and facts: MedlinePlus Medical Encyclopedia
March 22, 2019 - TGen and ABL pursue global rollout of advanced TB test
March 22, 2019 - Traffic light labels influence people to choose healthier and more sustainable meals
March 22, 2019 - Alzheimer’s patients using antiepileptic drugs have twice the risk of pneumonia, study shows
March 22, 2019 - Skin diseases may be more prevalent than previously thought
March 22, 2019 - Overall rates of death from breast cancer are falling across the EU
March 22, 2019 - Novel plasmid could hold key to control of mosquito-borne illness
March 22, 2019 - Female Emergency Physicians Paid Less Than Males
March 22, 2019 - Estimated average glucose (eAG): MedlinePlus Medical Encyclopedia
March 22, 2019 - Experimental drug could be new option for type 2 diabetes
March 22, 2019 - Five Things To Know About The Electronic Health Records Mess
March 22, 2019 - TMJ disorders could be treated with tissue-engineered implants after successful animal study
March 22, 2019 - Team-based approach is key to successful care of pregnant women with heart failure
March 22, 2019 - Study identifies gene variant associated with accelerated cellular aging
March 21, 2019 - Salk scientists show how background noise from neurons can interrupt focused attention
March 21, 2019 - New class of drugs could help treat patients diagnosed with ovarian cancer
March 21, 2019 - Tecentriq Approved for Small Cell Lung Cancer
March 21, 2019 - Adipocyte glucocorticoid receptors play a role in developing steroid diabetes
New flexible sensor can map blood-oxygen levels over large areas of the body

New flexible sensor can map blood-oxygen levels over large areas of the body

image_pdfDownload PDFimage_print

Berkeley — Injuries can’t heal without a constant influx of blood’s key ingredient — oxygen.

A new flexible sensor developed by engineers at the University of California, Berkeley, can map blood-oxygen levels over large areas of skin, tissue and organs, potentially giving doctors a new way to monitor healing wounds in real time.

“When you hear the word oximeter, the name for blood-oxygen sensors, rigid and bulky finger-clip sensors come into your mind,” said Yasser Khan, a graduate student in electrical engineering and computer sciences at UC Berkeley. “We wanted to break away from that, and show oximeters can be lightweight, thin and flexible.”

The sensor, described this week in the journal Proceedings of the National Academy of Sciences, is made of organic electronics printed on bendable plastic that molds to the contours of the body. Unlike fingertip oximeters, it can detect blood-oxygen levels at nine points in a grid and can be placed anywhere on the skin. It could potentially be used to map oxygenation of skin grafts, or to look through the skin to monitor oxygen levels in transplanted organs, the researchers say.

“All medical applications that use oxygen monitoring could benefit from a wearable sensor,” said Ana Claudia Arias, a professor of electrical engineering and computer sciences at UC Berkeley. “Patients with diabetes, respiration diseases and even sleep apnea could use a sensor that could be worn anywhere to monitor blood-oxygen levels 24/7.”

Existing oximeters use light-emitting diodes (LEDs) to shine red and near-infrared light through the skin and then detect how much light makes it to the other side. Red, oxygen-rich blood absorbs more infrared light, while darker, oxygen-poor blood absorbs more red light. By looking at the ratio of transmitted light, the sensors can determine how much oxygen is in the blood.

These oximeters only work on areas of the body that are partially transparent, like the fingertips or the earlobes, and can only measure blood-oxygen levels at a single point in the body.

“Thick regions of the body, such as the forehead, arms and legs, barely pass visible or near-infrared light, which makes measuring oxygenation at these locations really challenging,” Khan said.

In 2014, Arias and a team of graduate students showed that printed organic LEDs can be used to create thin, flexible oximeters for fingertips or earlobes. Since then, they have pushed their work further, developing a way of measuring oxygenation in tissue using reflected light rather than transmitted light. Combining the two technologies let them create the new wearable sensor that can detect blood-oxygen levels anywhere on the body.

The new sensor is built of an array of alternating red and near-infrared organic LEDs and organic photodiodes printed on a flexible material. The team used the sensor to track the overall blood-oxygen levels on the forehead of a volunteer who breathed air with progressively lower concentrations of oxygen — similar to going up in altitude — and found that it matched those using a standard fingertip oximeter. They also used the sensor to map blood-oxygen levels in a three-by-three grid on the forearm of a volunteer wearing a pressure cuff.

“After transplantation, surgeons want to measure that all parts of an organ are getting oxygen,” Khan said. “If you have one sensor, you have to move it around to measure oxygenation at different locations. With an array, you can know right away if there is a point that is not healing properly.”

Tagged with:

About author

Related Articles