Breaking News
March 24, 2019 - Enzyme inhibitor stops inflammation and neurodevelopmental disorders in mouse models
March 24, 2019 - Walk, Dance, Clean: Even a Little Activity Helps You Live Longer
March 24, 2019 - Americans used less eye care in 2014 versus 2008
March 24, 2019 - Study finds link between depression in 20s linked to memory loss in 50s
March 24, 2019 - New tool helps physiotherapy students to master complex fine motor skills
March 24, 2019 - The AMR Centre secures £2.3m funding boost
March 24, 2019 - Study examines effects of taking ondansetron during first trimester of pregnancy
March 24, 2019 - Researchers identify a more effective treatment for cancer
March 24, 2019 - Open-source solution for multiparametric optical mapping of the heart’s electrical activity
March 24, 2019 - New nanotechnology approach shows promise in treating triple negative breast cancer
March 24, 2019 - Trevena Announces Publication of APOLLO-1 Results in The Journal of Pain Research Highlighting Oliceridine’s Potential for Management of Moderate-to-Severe Acute Pain
March 24, 2019 - Maternal deaths following C-section 50 times higher in Africa compared to high-income countries
March 24, 2019 - Apple watch could detect irregular heart beat says study
March 24, 2019 - Queen Mary University of London’s BCI boosts radionuclide imaging capabilities with MILabs VECTor technology
March 24, 2019 - Girls should be encouraged to gain more ball skills, shows study
March 24, 2019 - Acute doses of synthetic cannabinoid can impair critical thinking and memory
March 24, 2019 - Presence of bacteria in urine does not always point to infection, shows study
March 24, 2019 - Scientists identify a new role for nerve-supporting cells
March 24, 2019 - Hidden differences between pathology of CTE and Alzheimer’s disease discovered
March 24, 2019 - Knowing causative genes of osteoporosis may open door to more effective treatments
March 24, 2019 - Toilet-seat based cardiovascular monitoring system getting ready to begin commercialization
March 24, 2019 - New model for intensive care identifies factors that send ill patients to ICU
March 24, 2019 - Recommendations Issued for HSCT in Multiple Myeloma
March 24, 2019 - Deep brain stimulation provides sustained relief for severe depression
March 24, 2019 - “Statistical significance” may soon be a thing of past?
March 24, 2019 - Researchers track effects of epigenetic marks carried by sperm chromosomes
March 24, 2019 - AHA News: Family Adopts Three Children With Three Different Heart Conditions
March 24, 2019 - Research into opioid painkillers could provide clues for safer drug development
March 23, 2019 - Lung cancer survivor recounts her lifetime struggles
March 23, 2019 - Radial and femoral approach for PCI achieve similar results in terms of survival
March 23, 2019 - Study sheds light on the optimal timing of coronary angiography in NSTEMI patients
March 23, 2019 - Excess hormones could cause a condition that can lead to blindness in women, study finds
March 23, 2019 - Dramatic shifts in first-time opioid prescriptions bring hope, concern
March 23, 2019 - Antidepressant drugs may not work when neurons are out of shape
March 23, 2019 - TTUHSC El Paso to establish endowed chair in neurology through a major grant
March 23, 2019 - New device approved by FDA for treating patients with moderate-to-severe heart failure
March 23, 2019 - People with peripheral artery disease have lower Omega-3 Index, shows research
March 23, 2019 - Trigger warnings have minimal impact on how people respond to content, shows research
March 23, 2019 - Gilead Announces Data From Two Studies Supporting Further Development of GS-6207, a Novel, Investigational HIV-1 Capsid Inhibitor as a Component of Future Long-Acting HIV Therapies
March 23, 2019 - Selfish genetic elements amplify inflammation and age-related diseases
March 23, 2019 - Study provides new understanding of how the brain recovers from damage caused by stroke
March 23, 2019 - CRISPR/Cas libraries could revolutionize drug discovery
March 23, 2019 - Allergic reaction during pregnancy may alter sexual-development in offspring’s brain
March 23, 2019 - Seeing through a robot’s eyes helps those with profound motor impairments
March 23, 2019 - Recent research shows that ease of breastfeeding after C-section differs culturally
March 23, 2019 - Newly discovered parameters offer more control over efficient release of drugs
March 23, 2019 - ‘De-tabooing’ of abortion- Women would like more support from health care community
March 23, 2019 - Anti-TB drugs can increase susceptibility to Mtb reinfection
March 23, 2019 - New survey indicates need of attention to neglected tropical diseases
March 23, 2019 - Innovative in vitro method to develop easy-to-swallow medicine for children and older people
March 23, 2019 - Sugary drinks could raise risk of early deaths finds study
March 23, 2019 - Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes
March 23, 2019 - Overall, Physicians Are Happy and Enjoy Their Lives
March 23, 2019 - Researchers discover how blood vessels protect the brain during inflammation
March 23, 2019 - CDC study shows modest improvement in optimal hospital breastfeeding policy
March 23, 2019 - Family-based prevention program to reduce alcohol use among older teens
March 23, 2019 - Remote monitoring of implanted defibrillators in heart failure patients prevents hospitalizations
March 23, 2019 - Appropriate doffing of personal protective equipment may reduce healthcare worker contamination
March 23, 2019 - Window screens can suppress mosquito populations, reduce malaria in Tanzania
March 23, 2019 - Researchers discover new biomarker for postoperative liver dysfunction
March 23, 2019 - Pregnancy history may be linked to cognitive function in older women, finds study
March 23, 2019 - Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack
March 23, 2019 - FDA Approves First Drug for Postpartum Depression, Zulresso (brexanolone)
March 23, 2019 - New guidelines outline new treatment management for psoriasis
March 23, 2019 - Thermally abused cooking oil may promote progression of breast cancer
March 23, 2019 - High-fructose corn syrup fuels growth of colon tumors in mice
March 23, 2019 - Partnership aims at establishing best practices to promote diversity in clinical trials
March 23, 2019 - New study examines presence of microbes in tap water from residences, office buildings
March 23, 2019 - Early life trauma may affect brain structure, contribute to major depressive disorder
March 23, 2019 - NIH starts clinical trial of drug to treat cravings associated with opioid use disorder
March 23, 2019 - Cervix bacteria, immune factors could be a warning signal of premature birth, reports new research
March 23, 2019 - Worst-ever emergency care performance figures underscore the need to focus on staffing
March 23, 2019 - The Current issue of “The view from here” is concerned with Cancer
March 23, 2019 - Mouse model validates how ‘good’ and ‘bad’ bacteria affect acne
March 23, 2019 - Individual amygdala neurons respond to touch, imagery and sounds
March 23, 2019 - Combination of two topical creams can prevent cancer
March 23, 2019 - Study suggests depression screening when assessing African-Americans for schizophrenia
March 23, 2019 - New electronic support system for choosing drug treatment based on patient’s genotype
March 23, 2019 - First-of-its-kind study provides pregnancy statistics of imprisoned U.S. women
March 23, 2019 - Marinus Pharmaceuticals Initiates Phase 3 Study in Children with PCDH19-Related Epilepsy
TBIMSC completes 30 years of collaborative research to improve TBI outcomes

TBIMSC completes 30 years of collaborative research to improve TBI outcomes

image_pdfDownload PDFimage_print

Over the past three decades, the Traumatic Brain Injury Model Systems Center (TBIMSC) program has served as a critical source of research to improve care and outcomes for patients and families affected by traumatic brain injury (TBI). The history and research achievements of the TBIMSC are reviewed in the November/December issue of the Journal of Head Trauma Rehabilitation (JHTR). The official journal of the Brain Injury Association of America, JHTR is published in the Lippincott portfolio by Wolters Kluwer.

“On the occasion of the 30th anniversary of the TBIMSC program, this article highlights many of the accomplishments of this well-established, multicenter TBI research consortium,” write Marcel P. Dijkers, PhD, of Icahn School of Medicine at Mount Sinai, New York City, and colleagues. In a special article, the authors focus on the recent research activities of the TBIMSC program – including its long-term National Database and efforts to “translate” research advances into improvements in the care and rehabilitation of patients with TBI.

Thirty Years of Collaborative Research to Improve TBI Outcomes The Traumatic Brain Injury Model Systems Centers were established by the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR) in 1987, with the goal of improving healthcare – especially rehabilitation care – and outcomes for patients with moderate-to-severe TBI. The original objective of the TBIMSC program was to demonstrate the value of coordinated medical, social, and vocational services for this group of patients, a group that had previously been placed in psychiatric hospitals or other long-term care facilities.

Currently, there are 16 funded TBIMSCs across the United States. All of these institutions carry out research activities connected to clinical care for patients with TBI, including emergency, acute, neurosurgical, and inpatient and outpatient rehabilitation services. The TBIMSCs perform site-specific and collaborative research to build the evidence base for advancing care and outcomes for patients with TBI. For the past decade, the TBIMSC program has collaborated with the Department of Veterans Affairs Polytrauma Research Centers, focusing on TBI as the “signature injury” of the Middle-East wars.

A central component of the program’s mission is the creation and maintenance of the TBI National Database. The database includes information on all eligible adult patients with moderate-to-severe TBI at each TBIMSC institution. Standardized data are collected at the time of initial injury, at one, two, and five years post-injury, and every five years thereafter. The first group of patients recently completed their 25th year of follow-up.

Since 1989, TBIMSC institutions have contributed about 16,500 patients to the TBI National Database, building a uniquely rich source of data to answer clinical questions and evaluate long-term outcomes after TBI. Ongoing efforts continue to assess and expand the quality and value of the data collected.

Over the years, the TBIMSCs have produced hundreds of research papers advancing the field of TBI care. The scope of research is broad, with outcomes including not only long-term health and functioning, but also social participation, employment, and quality of life. Research has also focused on new approaches for problems such as sleep and fatigue, emotional dysregulation, and memory and cognitive impairments.

Emerging initiatives include efforts to identify genetic or other factors to help in understanding why some patients with moderate-to-severe TBI have better outcomes than others. The TBIMSCs also collaborate with another NIDILRR initiative, the Model Systems Knowledge Translation Center, following a variety of strategies to ensure that research is “relevant and accessible” to people with disabilities and their families, as well as to researchers, clinicians, policy makers, and advocacy groups.

The TBIMSC program includes the largest research database for TBI in the world. Researchers continue to learn from the data collected in their efforts to advance the field. With a focus on relevance to stakeholders, the TBIMSCs’ have and continue to improve outcomes for individuals with TBI.

Source:

http://home.lww.com/news.entry.html/2018/11/07/traumatic_brain_inju-U3xV.html

Tagged with:

About author

Related Articles