Breaking News
February 20, 2019 - Self-reported sleep duration is a useful tool to measure sleep in children, study suggests
February 20, 2019 - T-cells play key role in how the body fights follicular lymphoma
February 20, 2019 - Study shows how 3D organization of genetic material helps perpetuate the species
February 20, 2019 - Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells
February 20, 2019 - Health Tip: Get Your Child to School on Time
February 20, 2019 - Shortcut strategy for screening compounds with clinical potentials for drug development
February 20, 2019 - Common acid reflux drugs tied to elevated risk for kidney disease
February 20, 2019 - Microbiome could be culprit when good drugs do harm
February 20, 2019 - Prenatal exposure to forest fires causes stunted growth in children
February 20, 2019 - Gene therapy restores hearing in mice with congenital genetic deafness
February 20, 2019 - First molecular test predicts treatment response for kidney cancer
February 20, 2019 - New method for improved visualization of single-cell RNA- sequencing data
February 20, 2019 - Researchers capture altered brain activity patterns of Parkinson’s in mice
February 20, 2019 - A possible blood test for detecting Alzheimer’s disease before symptoms show
February 20, 2019 - Primary care physicians associated with longevity, new research finds
February 19, 2019 - New study identifies many key lessons to establish sanctioned safe consumption sites
February 19, 2019 - Single CRISPR treatment can safely and stably correct genetic disease
February 19, 2019 - Multinational initiative to study familial primary distal renal tubular acidosis
February 19, 2019 - Breakthrough study highlights the promise of cell therapies for muscular dystrophy
February 19, 2019 - Subsymptom Threshold Exercise Speeds Concussion Recovery
February 19, 2019 - Midline venous catheters – infants: MedlinePlus Medical Encyclopedia
February 19, 2019 - Searching for side effects
February 19, 2019 - Humanity is all right, probably, although human extinction remains quite possible, researcher says
February 19, 2019 - Having Anesthesia Once as a Baby Does Not Cause Learning Disabilities, New Research Shows
February 19, 2019 - Anti-cancer immunotherapy could be used to fight HIV
February 19, 2019 - Customized Micropatterning for Improved Physiological Relevance
February 19, 2019 - Unique gene therapy approach paves new way to tackle rare, inherited diseases
February 19, 2019 - Activating gene that helps excite neurons reverses depression in male mice
February 19, 2019 - Science Puzzling Out Differences in Gut Bacteria Around the World
February 19, 2019 - Cells that destroy the intestine
February 19, 2019 - On recovery, vulnerability and ritual: An exhibit in white
February 19, 2019 - Scientific Duo Gets Back To Basics To Make Childbirth Safer
February 19, 2019 - COPD patients need more support when understanding new chest symptoms
February 19, 2019 - Using light-based method for production of pharmaceutical molecules
February 19, 2019 - Scientists find link between inflammation and cancer
February 19, 2019 - The High Cost Of Sex: Insurers Often Don’t Pay For Drugs To Treat Problems
February 19, 2019 - Hearing impairment associated with accelerated cognitive decline with age
February 19, 2019 - Researchers identify multiple genetic variants associated with body fat distribution
February 19, 2019 - Influenza and common cold are completely different diseases, study shows
February 19, 2019 - Scientists untangle how microbes manufacture key antibiotic compound
February 19, 2019 - Greater primary care physician supply associated with longer life spans
February 19, 2019 - HIV-1 protein suppresses immune response more broadly than thought
February 19, 2019 - Brain imaging indicates potential success of drug therapy in depressive patients
February 19, 2019 - For 2020 Dem Hopefuls, ‘Medicare-For-All’ Is A Defining Issue, However They Define It
February 19, 2019 - Specialized lung cells appear in the developing fetus much earlier than previously thought
February 19, 2019 - KU professor discusses promise of brain-computer interface to aid, restore communication
February 19, 2019 - Highly effective solution for detecting onset of aggregation in nanoparticles
February 19, 2019 - Early marker of cardiac damage triggered by cancer treatment identified
February 19, 2019 - Antidepressant drug could save people from deadly sepsis, research suggests
February 19, 2019 - CRISPR technology creates pluripotent stem cells that are ‘invisible’ to the immune system
February 19, 2019 - New study establishes how stress favors breast cancer growth and spread
February 19, 2019 - Midlife Systemic Inflammation Linked to Later Cognitive Decline
February 19, 2019 - Therapy derived from parasitic worms downregulates proinflammatory pathways
February 19, 2019 - Antimicrobial reusable coffee cups are less likely to become contaminated with bacteria, study shows
February 19, 2019 - Harnessing the evolutionary games played by cancer cells to advance therapies
February 19, 2019 - AHA News: Heart Transplant Survivor Gets Wedding Proposal at Finish Line
February 19, 2019 - HIV hidden in patients’ cells can now be accurately measured
February 19, 2019 - Research finds reasons for sudden cardiac death in patients with stable ischemic disease
February 19, 2019 - New protocol could help physicians to rule out bacterial infections in infants
February 19, 2019 - Women experiencing miscarriage should be offered treatment choices
February 19, 2019 - New protocol can help identify febrile infants at low risk for serious bacterial infections
February 19, 2019 - Innovative way to block HIV runs into a roadblock
February 19, 2019 - Springer Nature with BCRF conduct pilot project to make their research datasets more accessible
February 19, 2019 - Study finds neuromelanin-sensitive MRI as potential biomarker for psychosis
February 19, 2019 - Improvements in cardiovascular care for elderly save billions in health care costs
February 19, 2019 - Chilean food regulations are changing food perceptions and purchasing habits, study suggests
February 19, 2019 - Index endoscopy results are crucial for assessment of Barrett’s patients
February 18, 2019 - Breast cancer screening age should be lowered to 35
February 18, 2019 - Brain synchronization depends on the language of communication
February 18, 2019 - Drug Company Payments Over Time May Influence Rx Practices
February 18, 2019 - Despite socioeconomic gains, black-white ‘health gap’ remains
February 18, 2019 - Researchers report progress in the treatment of aggressive brain tumors
February 18, 2019 - Scientists discover trigger that turns strep infections into devastating disease
February 18, 2019 - Scanning children’s teeth may predict future mental health issues
February 18, 2019 - Health Highlights: Feb. 14, 2019
February 18, 2019 - New knowledge could help predict and prevent depression
February 18, 2019 - More primary care physicians leads to longer life spans | News Center
February 18, 2019 - Study examines link between supply of primary care physicians and life expectancy
February 18, 2019 - New study assesses screen time in young children
February 18, 2019 - Patented IU discovery to treat ARDS has been optioned to Theratome Bio
Neck scan detects dementia way before symptoms appear

Neck scan detects dementia way before symptoms appear

image_pdfDownload PDFimage_print

Researchers have shown that early dementia signs could be detected by a simple short scan of the individual’s neck. The actual dementia symptoms could be seen up to 10 years after these signs are visible on the scans they add. If proven robust for all cases, this test could soon become routine for screening middle aged individuals and classifying them as high risk for dementia later in life.

The researchers at the University College London (UCL) looked at the strength of a pulse travelling to the brain via the neck from the heart. The intensity of this pulse from the heart to different parts of the body often varies. The large blood vessels are normally elastic and they absorb the major pulse intensity from the heart due to their wall elasticity. This leads to diminishing the pulse intensity that travels to the brain and thus it prevents damage to the delicate and thin blood vessels of the brain, the team explains.

MRI brain of Dementia patient with left parietal atrophy asymmetry. Shutterstock / Atthapon Raksthaput

MRI brain of Dementia patient with left parietal atrophy asymmetry. Shutterstock / Atthapon Raksthaput

As a person ages, the wall elasticity of the arteries is lost and they become rigid. This means that the full intensity of the heart beat pulse reaches the brain via the stiffened arteries. This can damage the smaller and more delicate brain blood vessels which could eventually cause damage to the brain and its tissues leading to dementia. There are mini-strokes as these delicate blood vessels are damaged and they form new networks and undergo structural changes. These changes are all contributory to dementias, the authors explain.

For this study the team looked at around 3,200 middle-aged participants who were followed for an average of 15 years to see if they were at high risk of dementia. They underwent an ultrasound test of the neck in 2002 to see if their pulse intensity to the brain. In addition memory functions and problem solving tests were also conducted on these participants at baseline. Results showed that those who had the highest pulse intensity were 50 percent more likely to show an accelerated or rapidly progressing decline in cognitive abilities over the following 10 years compared to those who had a lower intensity. The team adjusted their results for other factors that may influence dementia risks such as age, blood pressure, obesity, presence of diabetes and other heart diseases.

According to the researchers, the neck scan could predict the “risk scores” for dementia later in life and increased pulse intensity was associated with a significant decline in memory, thinking, problem solving, language etc.

Dr Scott Chiesa, post-doctoral researcher at UCL in a statement said, “These findings demonstrate the first direct link between the intensity of the pulse transmitted towards the brain with every heartbeat and future impairments in cognitive function. It’s therefore an easily measurable and potentially treatable cause of cognitive decline in middle-aged adults which can be spotted well in advance.”

The study was co-funded by the British Heart Foundation. Professor Metin Avkiran, the associate medical director of the BHF said that this could soon become a tool to detect dementia way before symptoms appeared. He added, “What we need now is further research, for example to understand whether lifestyle changes and medicines that reduce pulse wave intensity also delay cognitive decline.” As of now keeping blood pressure and cholesterol levels in check with appropriate medication when prescribed, in addition to a healthy diet and regular exercise can help keep dementia at bay say the experts.

The team is presenting the results of this study at the American Heart Association Scientific Sessions conference in Chicago.

Tagged with:

About author

Related Articles