Breaking News
February 22, 2019 - AbbVie Announces New Drug Application Accepted for Priority Review by FDA for Upadacitinib for Treatment of Moderate to Severe Rheumatoid Arthritis
February 22, 2019 - Nature versus nurture and addiction
February 22, 2019 - New website connects researchers with data experts, resources | News Center
February 22, 2019 - Today’s Concerns About Drug Prices Echo The Past
February 22, 2019 - CT and Doppler equipment have low accuracy in detecting cerebral vasospasm and ischemia
February 22, 2019 - Study finds out similarity in function between healthy retina cell and tumor cell
February 22, 2019 - CWRU awarded NIH grant to identify effective treatments for intimate partner violence
February 22, 2019 - Oncotype DX Not Cost-Effective for Low-Risk Breast Cancer
February 22, 2019 - Scientists discover new type of immune cells that are essential for forming heart valves
February 22, 2019 - Talk About Déjà Vu: Senators Set To Re-Enact Drug Price Hearing Of 60 Years Ago
February 22, 2019 - Genetic defect linked to pediatric liver disease identified
February 22, 2019 - New cellular atlas could provide a deeper insight into blinding diseases
February 22, 2019 - Growing number of cancer survivors, fewer providers point to challenge in meeting care needs
February 22, 2019 - Innovative compound offers a new therapeutic approach to treat multiple sclerosis
February 22, 2019 - $1.5 million grant to develop opioid treatment program for jail detainees
February 22, 2019 - FDA’s new proposed rule would update regulatory requirements for sunscreen products in the U.S
February 22, 2019 - Most Hip, Knee Replacements Last Decades, Study Finds
February 22, 2019 - Wellness problems prevalent among ob-gyn residents
February 22, 2019 - In the Spotlight: “The world is your oyster in geriatrics”
February 22, 2019 - Successful testing of multi-organ “human-on-a-chip” could replace animals as test subjects
February 22, 2019 - Analysis of cervical precancer shows decline in two strains of HPV
February 22, 2019 - Sugary stent eases suturing of blood vessels
February 22, 2019 - From surgery to psychiatry: A medical student reevaluates his motivations
February 22, 2019 - Is New App From Feds Your Answer To Navigating Medicare Coverage? Yes And No
February 22, 2019 - New pacemakers powered by heartbeats could reduce need for surgery
February 22, 2019 - The United States records highest drug overdose death rates
February 22, 2019 - Phase 1 data reinforce safety profile of new drug for treating Duchenne muscular dystrophy
February 22, 2019 - Vitamin D supplementation less effective in the presence of obesity, shows study
February 22, 2019 - CPRIT awards nearly $20 million to The University of Texas MD Anderson Cancer Center
February 22, 2019 - Sarepta Announces FDA Acceptance of Golodirsen (SRP-4053) New Drug Application for Patients with Duchenne Muscular Dystrophy Amenable to Skipping Exon 53
February 22, 2019 - An institutional effort to reduce the amount of opioids prescribed following lumbar surgery
February 22, 2019 - Family-history-based models perform better than non-family-history based models
February 22, 2019 - Failure to take statins leads to higher mortality rates | News Center
February 22, 2019 - New study explains why some patients report phantom sensations after limb amputation
February 22, 2019 - First motor-controlled heart valves implanted by Mainz University Medical Center
February 22, 2019 - Novel preclinical model mimics persistent interneuron loss seen in preterm infants
February 22, 2019 - Global health burden of glaucoma has increased, study reveals
February 22, 2019 - A holistic approach key to minimize treatment complexity in patients with interstitial lung disease
February 22, 2019 - 1 in 10 middle-aged Chinese adults are at high risk for heart disease, finds study
February 22, 2019 - More than half a million breast cancer patient’s lives saved by improvements in treatment
February 22, 2019 - Study finds no evidence that tougher policies prevent teenage cannabis use
February 22, 2019 - New blood test detects genetic disorders in fetuses
February 22, 2019 - Lower Self-Perception Observed in Children With Amblyopia
February 22, 2019 - Up to 15 percent of children have sleep apnea, yet 90 percent go undiagnosed
February 22, 2019 - Rare pulmonary defect prompts parents’ nationwide search for answers | News Center
February 22, 2019 - Lesbian and bisexual women at greater risk of being overweight, study finds
February 22, 2019 - UQ research may explain why vitamin D is essential for brain health
February 22, 2019 - Heart Attacks Rising Among Younger Women
February 22, 2019 - How your smartphone is affecting your relationship
February 22, 2019 - Orthopaedic surgeon receives prestigious award, $10 million grant | News Center
February 22, 2019 - New sepsis test could save thousands of lives
February 22, 2019 - Cervical cancer could be eradicated by 2100
February 21, 2019 - Sustained smoking cessation can lower risk of seropositive RA
February 21, 2019 - Thousands with chronic UTIs are not receiving the treatment they need
February 21, 2019 - Are teens getting high on social media? The surprising study seeking the pot-Instagram link
February 21, 2019 - Stanford expands biobank services | News Center
February 21, 2019 - Scientists identify link between drinking contexts and early onset intoxication among adolescents
February 21, 2019 - Strong social support may reduce cardiovascular disease risk in postmenopausal women
February 21, 2019 - Rapid expansion of interventions could prevent up to 13 million cases of cervical cancer within 50 years
February 21, 2019 - Motif Bio Receives Complete Response Letter From The FDA
February 21, 2019 - Researchers map previously unknown disease in children
February 21, 2019 - A skeptical look at popular diets: Going gluten-free
February 21, 2019 - Podcast: KHN’s ‘What The Health?’ How Safe Are Your Supplements?
February 21, 2019 - Factors associated with increased risk of developing surgical site infections
February 21, 2019 - Anticipatory signals in eye movements can help measure attentive capacity, learning with greater precision
February 21, 2019 - Study explores daily exposure to indoor air pollutants
February 21, 2019 - Evening exercise does not negatively affect sleep, may also reduce hunger
February 21, 2019 - Artificial intelligence technique can be used to identify alcohol misuse in trauma setting
February 21, 2019 - Overweight, obesity in adolescence associated with increased risk of renal cancer later in life
February 21, 2019 - BGU develops new AI platform for monitoring and predicting ALS progression
February 21, 2019 - Researchers discover a new promising target to improve HIV vaccines
February 21, 2019 - Brief Anesthesia in Infancy Does Not Mar Neurodevelopment
February 21, 2019 - Gaming system helps with autism diagnosis
February 21, 2019 - Heart Disease: Six Things Women Should Know
February 21, 2019 - More States Say Doctors Must Offer Overdose Reversal Drug Along With Opioids
February 21, 2019 - Researchers explore case studies focused on industries that kill more people than employed
February 21, 2019 - Only half of GP practice buildings are fit for purpose
February 21, 2019 - Intense exercise, fasting and hormones can enhance waste-protein removal, study shows
February 21, 2019 - Scientists can monitor brain activity to predict epileptic seizures few minutes in advance
February 21, 2019 - Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats
Cessation fatigue predicts relapse rate after attempts to quit smoking

Cessation fatigue predicts relapse rate after attempts to quit smoking

image_pdfDownload PDFimage_print

Although there is good news about smoking — only 14 percent of Americans smoke, the lowest number ever, according to a 2017 National Health Interview Survey — challenges remain. In a given year, more than 40 percent of smokers make no attempt to quit. For those who do, it can take many tries — estimates vary from six to 30 — before they succeed, if they ever do. If more smokers are to succeed in staying quit, a better understanding of the factors that hinder them from meeting smoking cessation milestones is needed.

In the November issue of the Journal of Consulting and Clinical Psychology, investigators at the Medical University of South Carolina (MUSC) identify cessation fatigue — emotional exhaustion and reduced coping resources due to attempts to quit smoking or stay quit — as one such factor.

“We all know the stories of people who have tried and tried but repeatedly failed. Think about the cognitive and emotional toll that must take,” explains Matthew J. Carpenter, Ph.D., professor in the Department of Psychiatry and Behavioral Sciences at MUSC, a member of the Hollings Cancer Center and senior author on the article. “People get burnt out or exhausted from making repeated attempts and this study shows that has an effect on smoking cessation milestones.”

In the study, cessation fatigue, which was measured with a new multi-item scale for emotional exhaustion developed at MUSC, increased in the first six weeks of a quit attempt before plateauing. High cessation fatigue scores also predicted worse performance on important cessation milestones, such as time to quit attempt (for smokers who intended to quit) and relapse (for those already making a quit attempt). For both groups, those with higher scores on the emotional exhaustion scale, indicating a greater degree of cessation fatigue, were significantly less likely to have gone a full week without smoking at two months.

Why is this important? First, because cessation fatigue seems to be increasing just as other important predictors of relapse, such as withdrawal symptoms, are abating. Second, it offers a novel target for intervention strategies and helps identify those who would be most likely to benefit from those interventions.

“This could be like a triage where you could quickly give it to people and see where they’re at on this fatigue level,” says Bryan W. Heckman, Ph.D., assistant professor in the Department of Psychiatry and Behavioral Sciences at MUSC and first author on the article. “If they’re high or elevated, then that might be an intervention point to help them reduce their fatigue.”

A number of existing and developing intervention strategies could help reduce cessation fatigue. Pharmacological therapies already used in smoking cessation could be timed to ease cessation fatigue. Mobile health (mHealth) applications, which can reduce the logistical burden and stress of making a quit attempt, could be especially useful. For instance, Heckman is testing whether locations that prompt increases in urges to smoke can be programmed into an app using the GPS available on cell phones. When smokers making a quit attempt approach a location that they associate with smoking, they would automatically receive a push notification from the app to take a nicotine lozenge to help stave off the temptation to smoke.

“If we automate treatment using apps and reduce the amount of effort that people need to put into quit attempts, that could end up reducing fatigue over time,” says Heckman.

“Using these mHealth technologies, we both automate and personalize,” adds Carpenter. “Instead of giving blanket advice to twenty people, we can tailor therapy to each individual.”z

Next steps will be a longer-term study of the effects of cessation fatigue on quit attempts. Once cessation fatigue and its time course are better understood, more mHealth interventions targeting it will be developed and tested. Heckman and Carpenter also think it would be worthwhile to explore cessation fatigue in those making quit attempts for different substances of abuse or in those making other efforts at lifestyle change.

“I don’t think this is just about addictions and smoking,” says Carpenter. “This is about health behavior change. Think about anything that anybody tries to do that’s hard. It takes time. To say that you’re going to be one hundred percent committed on every day of your life in that attempt is folly. It’s a process. It takes a toll on you. Now we can look at this as a process and quantify that fatigue over time and see how it matters.”

Tagged with:

About author

Related Articles