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Researchers uncover large-scale brain patterns and networks which control sleep

Researchers uncover large-scale brain patterns and networks which control sleep

An international study headed by researchers from Aarhus University has for the first time uncovered the large-scale brain patterns and networks in the brain which control sleep, providing knowledge which in the future may can in the long term help the many Danes large proportion of people who experience problems sleeping.

We spend approximately. one-third of our life asleep and our sleep has fascinated researchers for many years. Research from the Center for Music in the Brain at Aarhus University and the University of Oxford has now revealed, in unprecedented detail, the patterns and networks used by the brain during sleep. The researchers have used a technique called functional MRI together with algorithms that can identify brain activity patterns.

“This provides a new and potentially revolutionary understanding of brain activity during sleep which can in turn lead to new forms of treatment of the sleep problems that affect far too many people,” explains postdoc at the Center for Music in the Brain at Aarhus University, Angus Stevner, who is behind the study.

The results have just been published in Nature Communications.

“Our results can change the way in which we understand sleep and, not least, the way we look at sleep disorders such as insomnia. We hope to be able to utilize this new and detailed categorization of sleep to identify changes in the brain activity of people suffering from certain with unexplained sleep disorders, such as dyssomnia or insomnia, which we currently cannot explain” explains states Angus Stevner.

Can help with sleep problems

Sleep has traditionally been divided into four stages which all produce different brain waves as a result of the brain’s electrical activity, ranging from light sleep – the first stage – to deep sleep and the special REM (rapid eye movement) sleep, and back again.

“This way of dividing sleep into stages is really based on historical conventions, many of which date back from to the 1930s. We’ve come up with a more precise and detailed description of sleep as a higher number of brain networks which change their communication patterns and dynamic characteristics during sleep,” says Angus Stevner.

Almost half of the Danish population experience sleep problems. The researchers hope that a more complete and detailed representation of how the brain’s networks changes during sleep can help them develop better models of the role played by sleep.

New knowledge about brain activity while we sleep

“At the moment we lack a consistent understanding of what’s happening in the brain of someone suffering from insomnia, but also of the role sleep has in mental disorders, where sleep disorders are all-pervadingextremely common,” says the researcher.

In recent years, progress made in modern brain scanning techniques has led to a far more nuanced understanding of the brain’s complexity, which the traditional sleep stages do not take into account.

“Our results provide a modern description of human sleep as a function of the brain’s complex network activities and we’re trying to move on from the somewhat simplified picture that has thus far characterized our understanding of brain activity during sleep,” he says.

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