Despite declines in cancer incidence rates among HIV-infected people, cancer will remain a significant concern as this patient population ages. By 2030, prostate and lung cancers are projected to be the most common cancers among individuals aging with HIV. The findings are published in Annals of Internal Medicine. Due to their weakened immune systems, people […]Continue Reading ...
Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia An international team of researchers including USC scientists has found scores of new genetic markers in DNA code that increase prostate cancer risk—powerful knowledge likely to prove useful to detect and prevent the disease. Focusing on DNA of more than 140,000 […]Continue Reading ...
Credit: CC0 Public Domain The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators. Whole genome sequencing of tumours revealed mutations which are targetable by existing drugs used to treat lung cancer and melanoma. The results, published today […]Continue Reading ...
A new study reveals that pediatric neuroblastoma patients are at elevated risk for long-term psychological impairment. In addition, those who experience such impairment as they get older tend to require special education services and to not go on to college. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer […]Continue Reading ...
Joseph A. Fraietta, Ph.D. (left) and J. Joseph Melenhorst, Ph.D. (right) Credit: Penn Medicine The doctors who have spent years studying the case call it “a series of fortunate events.” What began as a remarkable response to chimeric antigen receptor (CAR) T cell therapy is now providing evidence about the human genome and immune response […]Continue Reading ...
Killer T cells surround a cancer cell. Credit: NIH A cancer treatment that can completely destroy cancer cells without affecting healthy cells could soon be a possibility, thanks to research led by Cardiff University. The team of researchers has successfully ‘trained’ a respiratory virus to recognise ovarian cancer and completely destroy it without infecting other […]Continue Reading ...
Credit: Imperial College London A breath test can successfully detect oesophageal and gastric cancer and could be used as a first-line test for patients, say researchers. In a multi-centre clinical trial of 335 patients, the breath test can identify cancer from benign diseases with 85 per cent accuracy. Unlike other methods, the test is non-invasive. […]Continue Reading ...
Electron microscopic image of a single human lymphocyte. Credit: Dr. Triche National Cancer Institute Anyone who’s taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure […]Continue Reading ...
Austrian researchers have discovered that a small number of patients taking targeted drugs known as Janus kinase (JAK) inhibitors to treat myelofibrosis may develop aggressive lymphomas. They also speculate that screening for a preexisting B-cell clone before starting therapy may help prevent this side effect and potentially save lives, according to a study published online […]Continue Reading ...
Paul B. Fisher, M.Ph., Ph.D., F.N.A.I., Thelma Newmeyer Corman Endowed Chair in Cancer Research and member of the Cancer Molecular Genetics research program at VCU Massey Cancer Center, chairman of the Department of Human and Molecular Genetics at VCU School of Medicine and director of the VCU Institute of Molecular Medicine Credit: VCU Massey Cancer […]Continue Reading ...
Human cancer cells in a culture. Credit: Matthew Daniels Early results from a small-scale clinical trial have revealed the potential of a virus to treat some advanced cancers. The findings, presented by scientists from the University of Leeds at the annual meeting of the American Society for Clinical Oncology, revealed that the specifically-engineered virus was able […]Continue Reading ...
An illustration and summary of the four strategies (free to use for news purposes). Credit: Catrin Jakobsson Cancer cells in children tend to develop by following four main trajectories—and two of them are linked to relapse of the disease, according to a study led by Lund University in Sweden, now published in Nature Genetics. The […]Continue Reading ...
An updated American Cancer Society guideline says colorectal cancer screening should begin at age 45 for people at average risk, based in part on data showing rates of colorectal cancer are increasing in young and middle-aged populations. The new recommended starting age is based on colorectal cancer (CRC) incidence rates, results from microsimulation modeling that […]Continue Reading ...
In a Journal of Bone and Mineral Research study that followed 186 children with Acute Lymphoblastic Leukemia (ALL) for 6 years after initiation of chemotherapy, approximately 1 in 5 children experienced a non-vertebral fracture and 1 in 3 had a new vertebral fracture. Vertebral fractures were asymptomatic in 39 percent of the children, and approximately […]Continue Reading ...
Credit: CC0 Public Domain Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers. The researchers found that bladder cancer patients who had mutations in their ATM or RB1 genes—proteins that help repair DNA damage when they’re functioning normally—tended […]Continue Reading ...
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