Killer T cells surround a cancer cell. Credit: NIH Scientists at the VIB-UGent Center for Medical Biotechnology have taken important steps toward the development of cancer-targeting immunotherapy. The research team developed a treatment in mice that destroys part of the tumor and stimulates the immune system to attack persistent surviving cancer cells. In addition, the […]Continue Reading ...
Cancer cell during cell division. Credit: National Institutes of Health A retrospective study led by researchers at Baylor College of Medicine and The University of Texas Health Science Center at Houston (UTHealth) School of Public Health found that survivors of HPV-associated cancers have a high incidence of developing second HPV-related cancers. Their findings, which were […]Continue Reading ...
Credit: CC0 Public Domain An analysis of more than a decade of U.S. nursing home data has shown that breast cancer surgery is associated with high rates of mortality and hospital readmission, along with loss of functional independence, for frail nursing home residents. In a study appearing Aug. 29, 2018, in JAMA Surgery, UCSF researchers […]Continue Reading ...
Dr. Ralph Deberardinis and his Lab Manager, Jessica Sudderth, looking at a western blot. Credit: UT Southwestern In order to halt the growth of cancer cells, you have to know what feeds them. Researchers at the nationally recognized Kidney Cancer Program at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center have developed a novel approach […]Continue Reading ...
Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Image created in 2014 by Tom Misteli, Ph.D., and Karen Meaburn, Ph.D. at the NIH IRP. Certain types of breast tumors can send signals that freeze the growth of their own secondary cancers, according […]Continue Reading ...
The diagram shows the use of the new inhibitor for the treatment of triple-negative breast cancer. Credit: HKBU Chemists at Hong Kong Baptist University (HKBU) have discovered the use of a metal compound that inhibits the enzyme closely associated with triple-negative breast cancer (TNBC), one of the most difficult forms of breast cancer to treat. […]Continue Reading ...
A microscopic view of an invasive squamous cell cancer that stemmed from a rare skin disorder called recessive dystrophic epidermolysis bullosa (RDEB), or Butterfly Syndrome. Credit: Andrew South It is well known that extended exposure to the sun’s UV rays can cause DNA mutations that lead to skin cancer. Now new research reveals that inflammation from […]Continue Reading ...
This electron microscopic image of two Epstein Barr Virus virions (viral particles) shows round capsids—protein-encased genetic material—loosely surrounded by the membrane envelope. Credit: DOI: 10.1371/journal.pbio.0030430.g001 Epstein-Barr Virus (EBV) doesn’t directly cause cancer, but infection with this common herpes virus brings an increased risk of some cancers, including fast-growing lymphomas. This week in mSphere, researchers report […]Continue Reading ...
The American Association for Cancer Research (AACR) today released its annual Cancer Progress Report highlighting how federally funded research discoveries are fueling the development of new and even more effective ways to prevent, detect, diagnose, and treat cancer. Key advances outlined in the AACR Cancer Progress Report 2018 include the following: Twenty-two treatments for cancer […]Continue Reading ...
Artistic rendering of the surface of a human dendritic cell illustrating sheet-like processes that fold back onto the membrane surface. Credit: National Institutes of Health (NIH) For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published […]Continue Reading ...
Killer T cells surround a cancer cell. Credit: NIH Researchers have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer. Their findings, published in eLife, suggest the percentage of a tumor’s genome with alterations in copy number (or ‘copy number alteration’; CNA) […]Continue Reading ...
An aggressive brain tumor (glioblastoma), illustrated based on magnetic resonance data. Credit: Karl-Heinz Nenning Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than […]Continue Reading ...
Credit: CC0 Public Domain Patients with muscle-invasive bladder cancer have been shown to benefit from chemotherapy prior to surgical removal of the bladder. But which type of chemotherapy leads to the best outcomes in terms of complete response rates or cancer control? Moffitt Cancer Center researchers examined data from more than 800 surgical patients with […]Continue Reading ...
Melanoma in skin biopsy with H&E stain — this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0 In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy. The predictor […]Continue Reading ...
The effects of p53 in cancer-associated fibroblasts on cancer cell migration: Cancer cells (magenta) migrate in the direction of cancer-associated fibroblasts (yellow) that express a non-mutated p53 gene (left); this migration slows down (center) when the p53 in the fibroblasts is silenced; when substances released by the cancer-associated fibroblasts are added to the laboratory dish, […]Continue Reading ...
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