Dr. Johanna DiStefano, a TGen Professor and head of the institute’s Diabetes and Fibrotic Disease Unit. Credit: TGen DNA methylation is a molecular process that helps enable our bodies to repair themselves, fight infection, get rid of environmental toxins, and even to think. But sometimes this process goes awry. A team of scientists led by […]Continue Reading ...
Figure 1: Hypothesis for the onset mechanism of childhood steroid-sensitive nephrotic syndrome. Credit: Kobe University Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related to the development of childhood nephrotic syndrome. The results of this study could […]Continue Reading ...
Kendra Snyder, right, talks with patrons at Checkers Bar & Grill in Mount Union, Pa., on Monday, July 16, 2018. At age 12, Snyder passed out from a condition where her heart was missing over 1,000 beats every day. She had heart surgery for it when she turned 20, and doctors said the problem seemed […]Continue Reading ...
Research scientist Kwan Young Lee, left, molecular and integrative physiology professor Nien-Pei Tsai and their colleagues discovered that an overabundance of the tumor suppressor protein p53 in neurons can lead to impaired regulation of neuronal excitability in a mouse model of Fragile X syndrome. Credit: Steph Adams In a new study in mice, researchers have […]Continue Reading ...
Credit: Cardiff University A biological switch that could potentially regulate gene drive technology has been created by researchers from Cardiff University. The switch, a cheap and non-toxic amino acid called BOC, could switch proteins ‘on’ and ‘off’ in any species and offers promise in a whole host of fields, from pest control to regenerative medicine. […]Continue Reading ...
Credit: CC0 Public Domain Researchers at the Stanford University School of Medicine have found a way to predict whether someone exposed to the flu virus is likely to become ill. Purvesh Khatri, Ph.D., associate professor of medicine and of biomedical data science, and his team used a computational approach to pinpoint a blood-based genetic biomarker […]Continue Reading ...
Credit: CC0 Public Domain Psychiatric disorders such as schizophrenia and bipolar disorder often run in families. In a new international collaboration, researchers explored the genetic connections between these and other disorders of the brain at a scale that far eclipses previous work on the subject. The team determined that psychiatric disorders share many genetic variants, […]Continue Reading ...
This stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is dividing. Introns are regions often found in eukaryote genes that are removed in the splicing process (after the DNA is transcribed into RNA): Only the exons encode the […]Continue Reading ...
Graphic representation of the study. Credit: Sigrid Knemeyer, SciStories LLC The idea of testing blood or urine to find markers that help diagnose or treat disease holds great promise. But as technology has improved to allow researchers to examine tiny fragments of RNA, one major problem has led to limited success. “Different people are using […]Continue Reading ...
Credit: CC0 Public Domain A trio of researchers at the University of Cambridge School of Clinical Medicine has uncovered genes that appear to play a role in a person’s propensity for loneliness, and to some degree, how social they are. In their paper published in the journal Nature Communications, Felix Day, Ken Ong and John […]Continue Reading ...
A group of seven patients presenting with a similar disorder of unknown origin now know of a possible genetic root of their condition. A team of researchers sequenced all the protein-coding genes in the patients’ genomes and identified four different mutations in the gene TRAF7. The researchers report in the American Journal of Human Genetics […]Continue Reading ...
The pioneering technique UD Professor Adam Marsh developed to analyze the genetic activity of Antarctic worms is proving valuable for human health care research. Credit: University of Delaware/ Jeffrey Chase When University of Delaware molecular biologist Adam Marsh was studying the DNA of worms living in Antarctica’s frigid seas to understand how the organisms managed […]Continue Reading ...
Colm Nestor, Assistant Professor, Linköping University. Credit: Linköping University An error in one of the most widely used methods in epigenetics, DIP-seq, can cause misleading results, researchers at Linköping University, Sweden, have shown. This may have major significance in the research field, where Big Data and advanced methods of DNA analysis are used to study […]Continue Reading ...
Credit: CC0 Public Domain Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients. A UT Southwestern study that used genetic data from more than 1,200 participants may help scientists improve treatments of neuromyelitis optica (NMO). […]Continue Reading ...
Credit: University of Queensland A genetic defect affecting normal development in children has been identified by a study involving University of Queensland researcher and alumnus Professor David Coman. The study revealed that mutations in the gene FDFT1 prevented children from producing enough cholesterol, causing physical abnormalities. Professor Coman said cholesterol is critical for normal development […]Continue Reading ...
- Researchers create the world’s first artificial retina
- Yale researchers identify racial disparities in prescribing opioids for chronic pain
- BOOST-3 clinical trial aims to improve outcomes for severe TBI patients
- New study highlights Alzheimer’s herpes link, experts say
- Airline crew don’t have significantly elevated risk of thyroid cancer, new study finds
- States leverage federal funds to help insurers lower premiums
- New badge course explores research around skeletal muscle as an endocrine organ
- TG Therapeutics Announces Completion of Target Enrollment in the ULTIMATE Phase 3 Trials in Multiple Sclerosis
- Increased levels of human herpesvirus ID’d in Alzheimer’s
- To help patients quash pain, researcher develops practical guide for health care providers
- Medicine on the front line to be presented at Medical Innovation 2018
- Harbour Biomed and Kelun-Biotech collaborate to develop, commercialize anti-PD-L1 antibody
- The man who sold America on vitamin D — and profited in the process
- Finding the light in antimicrobials
- Unique pain program helps surgical patients wean off opioids safely and effectively
- Strawberries could mitigate colonic inflammation
- FDA Accepts New Drug Application (NDA) to Review Midazolam Nasal Spray, an Investigational Product for the Acute Treatment of Seizure Clusters
- Using Facebook to help young adults quit smoking
- ‘Liquid biopsy’ predicts lymphoma therapy success within days | News Center
- 5 Questions with Jordan Orange, Chair of Pediatrics