An expert committee of psychiatrists and geneticists has issued revised guidelines for the use of genetic testing in psychiatric care. The new guidelines, which represent the first complete revision since 2014, address several controversial questions, including the use of genetic testing to guide treatment decisions (pharmacogenetics), diagnosis of mental disorders with powerful new molecular genetic […]Continue Reading ...
Credit: CC0 Public Domain A team of researchers from the U.S., Australia and Denmark has found evidence of the prenatal environment tuning genomic imprinting. In their paper published in Proceedings of the National Academy of Sciences, the group describes their analysis of genomic data from several prior studies and what they found regarding genomic imprinting. […]Continue Reading ...
Immunofluorescence detection of the CLAG3 proteins, which play a role in resistance to some antimalarial compounds. Credit: Mira et al, 2019 Resistance to antimalarial drugs is thought to result mainly from changes in the parasite’s genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new study […]Continue Reading ...
Brain tissue reveals scar formation (at left) and inflammation (on right) in mice after stroke. Bottom images show less scarring and inflammation (in red) in animals treated with the drug maraviroc, which blocks the CCR5 gene. Credit: UCLA/Carmichael lab More than 6 million Americans live with disabilities following a stroke. Even mild strokes can leave […]Continue Reading ...
(From left) Researchers Ted Allison, Tim Footz and Gavin Neil in Allison’s zebrafish lab at the University of Alberta. The trio worked with medical geneticist Michael Walter to discover a gene that causes a type of glaucoma that strikes young males. Credit: Jordan Carson An international team of researchers has identified a gene responsible for […]Continue Reading ...
Credit: CC0 Public Domain A newly discovered ribosomal DNA (rDNA) clock can be used to accurately determine an individual’s chronological and biological age, according to research led by Harvard T.H. Chan School of Public Health. The ribosomal clock is a novel biomarker of aging based on the rDNA, a segment of the genome that has […]Continue Reading ...
Credit: CC0 Public Domain The use of alcohol and tobacco is closely linked to several diseases, and is a contributing factor in many deaths. A recent study using data from 1.2 million people has now been published in the journal Nature Genetics. Several research groups around the world are involved, among them a group from […]Continue Reading ...
Credit: CC0 Public Domain Researchers at the Leiden University Medical Center (LUMC), in collaboration with Delft University of Technology, have found a way to reset a racing heart immediately and automatically with an implanted LED device. In the scientific journal Science Translational Medicine, they describe how their bioelectronic defibrillator works in the laboratory. It could […]Continue Reading ...
New research suggests an earlier emergence of malaria in Africa. Credit: Institut Pasteur Malaria claims hundreds of thousands of lives each year—mainly children, and especially in Africa. It is one of the leading causes of death by an infectious agent, the Plasmodium falciparum parasite. In research on malaria, the genetic mutation that causes sickle cell […]Continue Reading ...
Magnetic resonance imaging of the brain. Credit: McGill University Health Centre An international effort led by physician-scientists at Rady Children’s Institute for Genomic Medicine (RCIGM), in collaboration with a team at the Montreal Children’s Hospital of the McGill University Health Centre (MCH-MUHC), has identified the cause of a devastating pediatric brain disorder paving the way […]Continue Reading ...
Credit: CC0 Public Domain Obesity is a major public-health problem in the United States and around the world, with an estimated 650 million people suffering from the condition. One of the biggest challenges of this ever-worsening condition is figuring out why people become obese in the first place, and why some people are more vulnerable […]Continue Reading ...
Neurons in the rat nucleus accumbens — a key brain reward structure — were targeted for CRISPR-based gene activation. Fluorescent reporter molecules mark the protein product of a gene targeted for activation (green), neurons expressing a CRISPR guide RNA (red), and DNA (blue). Credit: Katherine Savell and Nancy Carullo, UAB A powerful new tool is […]Continue Reading ...
Roche is boosting its presence in gene therapy research by buying US company Spark Therapeutics Swiss pharmaceuticals giant Roche said Monday it reached a deal worth $4.3 billion (3.7 billion euros) to buy US group Spark Therapeutics, which specialises in the development of gene therapy drugs. Roche said the deal was approved by the boards […]Continue Reading ...
- Toilet seat heart monitoring system
- Researchers identify way to improve common treatment for PTSD
- High potency cannabis use linked to psychosis finds study
- Evoke Pharma Submits Response to FDA Review Letter for Gimoti NDA
- Tracking HIV’s ever-evolving genome in effort to prioritize public health resources
- Scientists grow most sophisticated brain organoid to date
- ADHD drug raising risk of psychosis
- FDA approves brexanolone, first drug developed to treat postpartum depression
- Gruesome cat and dog experiments by the USDA exposed
- Ball pits used in children’s physical therapy may contribute to germ transmission
- Long-term use of inexpensive weight-loss drug may be safe and effective
- FDA Approves Sunosi (solriamfetol) for Excessive Daytime Sleepiness Associated with Narcolepsy or Obstructive Sleep Apnea
- Anti-Müllerian Hormone Test: MedlinePlus Lab Test Information
- Finding the right exercise, diet aids for HIV patients
- Health Plans For State Employees Use Medicare’s Hammer On Hospital Bills
- Researchers develop new tool for imaging large groups of neurons in living animals
- Certain bacteria and immune factors in vagina may cause or protect against preterm birth
- Novel breath test could pave new way to non-invasively measure gut health
- Pharmaceutical and personal care products may result in new contaminants in waterways
- ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib