HIV infecting a human cell. Credit: NIH A study published in The Lancet HIV shows that HIV-2 is more pathogenic than previously demonstrated. The new findings indicate that early treatment should be applied to all patients with HIV, not only to those with HIV-1. “The study is unique in that we have followed cohort of […]Continue Reading ...
Peer leader speaks to the sex worker community at the annual Baraza (community meeting) in Nairobi, Kenya. Credit: Julie Lajoie, Author provided With nearly two million new infections and one million associated deaths each year, the HIV (human immunodeficiency virus) pandemic is alive and well. Thirty-seven million people are now living with HIV, more than […]Continue Reading ...
Scanning electron micrograph of HIV-1 budding (in green) from cultured lymphocyte. This image has been colored to highlight important features; see PHIL 1197 for original black and white view of this image. Multiple round bumps on cell surface represent sites of assembly and budding of virions. Credit: CDC / C. Goldsmith, P. Feorino, E. L. […]Continue Reading ...
The WHO recommends HIV viral load testing to monitor people on ARVs. Credit: Shutterstock A United Nations initiative backed by global experts has set its sights on an ambitious programme to bring an end to the AIDS epidemic by 2030. The 90-90-90 strategy aims to do this by reaching three targets: 90% of all people […]Continue Reading ...
HIV infecting a human cell. Credit: NIH With more than 35 million people worldwide living with the virus and nearly 2 million new cases each year, the human immunodeficiency virus (HIV) remains a major global epidemic. Existing antiretroviral drugs do not cure HIV infection because of the virus’s ability to become dormant, remaining present but […]Continue Reading ...
HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia In a proof-of-principle study, researchers at Johns Hopkins report that a certain liver immune cell called a macrophage contains only defective or inert HIV-1 copies, and aren’t likely to restart infection on their own in HIV-1-infected people on long-term antiretroviral therapy (ART). The study, the investigators say, strongly suggest […]Continue Reading ...
Credit: CC0 Public Domain In the quest to develop a vaccine that triggers the immune system to prevent HIV infection, researchers have focused on identifying and eliciting a particular type of antibody that is capable of neutralizing the virus. These broadly neutralizing antibodies, or bnAbs, eventually arise naturally in about half of HIV-infected people, but […]Continue Reading ...
The researchers’ anti-integrin therapy using the approved medication vedolizumab (VDZ) reduced aggregates of immune cells (green) in intestinal biopsies from a patient with HIV and IBD. Credit: M. Uzzan et al., Science Translational Medicine (2018) In a study published today in Science Translational Medicine, Mount Sinai researchers describe for the first time a mechanism that […]Continue Reading ...
Credit: CC0 Public Domain A persistent challenge in HIV/AIDS treatment and prevention is medication adherence – getting patients to take their medication as required to get the best results. Currently, a once-daily pill to prevent HIV infection is available. However, adherence to a once-daily regimen can be difficult for some people. Researchers from the UNC […]Continue Reading ...
Credit: CC0 Public Domain An international team that includes Rutgers scientists has made significant progress in developing a urine diagnostic test that can quickly, easily and inexpensively identify tuberculosis infection in people also infected with HIV. TB is the leading infectious disease killer in the world and the most common cause of death for people […]Continue Reading ...
Credit: CC0 Public Domain Research has shown that drug and alcohol use interferes with anti-retroviral medication adherence among gay and bisexual men (GBM) living with HIV. There is limited parallel examination of whether the same holds true for pre-exposure prophylaxis (PrEP) adherence among HIV-negative GBM. In a study published this month in the journal AIDS […]Continue Reading ...
Credit: CC0 Public Domain This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child’s life. In 2017, doctors from the Transplant Unit at the Wits Donald Gordon Medical Centre performed what is believed to be the world’s first intentional liver transplant from a mother living with HIV […]Continue Reading ...
Credit: Mary Ann Liebert, Inc., publishers Diagnosis of HIV-1 infection in the 4-year old child of an HIV-negative mother led to a forensic analysis to determine the source of the infection and try to date the transmission of the virus. The results of genetic, phylogenetic, and serologic data analysis on both the father and son […]Continue Reading ...
That men who have sex with men run a greater risk of HIV than others has been known since the virus was discovered. However a thesis from Karolinska Institutet now shows that it is a small sub-group of these men who account for the greater part of the risk increase. The results are important to […]Continue Reading ...
Marina Caskey, a researcher who is part of a new clinical trial that shows that broadly neutralizing antibodies can suppress HIV for up to four months, far longer than currently available drugs. Credit: Mario Morgado/The Rockefeller University Thanks to improvements in antiretroviral therapy, HIV is now a manageable condition. Yet even the best drugs do […]Continue Reading ...
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