Credit: CC0 Public Domain The International Antiviral Society-USA Panel has released updated recommendations for the treatment and prevention of HIV infection in adults, published in the Journal of the American Medical Association. Michael Saag, M.D., director of the University of Alabama at Birmingham’s Center for AIDS Research, served as the article’s lead author. The recommendations, […]Continue Reading ...
Thousands of experts and activists descend on Amsterdam Monday to bolster the battle against AIDS amid warnings that “dangerous complacency” may cause a resurgence of the epidemic that has already killed 35 million people. Rather than closing in on the goal of “ending” AIDS, new HIV infections have surged in parts of the world as […]Continue Reading ...
Credit: The City University of New York HIV testing is a first step and key to stemming the rate of HIV infections around the world. In sub-Saharan African countries, HIV testing rates continue to be suboptimal, creating an urgent need to explore strategic and cost-effective approaches to increase the uptake of HIV testing, particularly among […]Continue Reading ...
Credit: CC0 Public Domain Public health officials are expanding efforts to get the HIV prevention pill into the hands of those at risk, in a nationwide effort to curb infections. But the officials are hitting roadblocks—the drug’s price tag, which has surged in recent years, and changes in insurance coverage that put a heftier financial […]Continue Reading ...
Simplified schematic of HIV transmission. After exposure to HIV through unprotected sexual contact, HIV has to pass several physiological barriers in the exposed individual (e.g. mucosal barrier) to reach a cellular compartment, where it can replicate in sufficient numbers to establish a systemic infection. However, not every exposure leads to infection. HIV prophylaxis with anti-HIV […]Continue Reading ...
HIV infecting a human cell. Credit: NIH Multiple barriers may stop high-risk individuals from accessing an HIV drug that can reduce the subsequent risk of infection, according to a new University of Michigan study. Researchers outlined solutions that would help overcome barriers that make it harder for underserved populations to access pre-exposure prophylaxis (PrEP). The […]Continue Reading ...
Brains are composed of different cell types and the image from microscopy shows what cells EcoHIV infects in a mixture of mouse brain cells in tissue culture. The colors label specific elements in the cell mixture: blue shows DNA found in all cells, red shows a specific protein CD11b that is found in microglia, the […]Continue Reading ...
Credit: CC0 Public Domain A group of men who may be underestimating their HIV risk has been identified in a new study. Public health messages should be targeted specifically at this neglected group, suggest researchers who carried out the work. The men are a distinct group who have sex with other men, but are not […]Continue Reading ...
HIV infecting a human cell. Credit: NIH Researchers have reported the results of the first randomised clinical trial to test a novel strategy involving waking up and then killing the ‘sleeping’ HIV that is hiding in the body using an experimental approach known as ‘kick and kill’. Led by Imperial College London, the University of […]Continue Reading ...
Inositol hexakisphosphate fits into the pore structures (pink) of the HIV capsid (teal), and makes the makes the capsid stronger, protecting the genetic material inside. Credit: UNSW Scientists from UNSW Sydney and the UK have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being […]Continue Reading ...
European patents expired on July 25 for Truvada, allowing EU authorities to clear the way for cheaper generics to enter the market Patient associations on Thursday lauded an EU decision to allow the sale of generic versions of Truvada, an anti-retroviral medicine used by those diagnosed HIV-positive, the virus causing AIDS. “This decision is historic […]Continue Reading ...
Carolina del Real, 37, was diagnosed as HIV positive seven years ago, and now devotes her time to teaching people about prevention The winds of change are blowing through Chile where a youthful sexual revolution is shattering taboos—but also sparking an explosion of HIV cases that has set off alarm bells in the traditionally conservative […]Continue Reading ...
Credit: pixabay By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells. Human immunodeficiency virus-1 (HIV-1) infection is a chronic disease affecting more than 35 million people worldwide. The infection can be controlled by […]Continue Reading ...
Credit: CC0 Public Domain In the first study to comprehensively describe where people are diagnosed with HIV in England, Wales, and Northern Ireland, investigators found that an increasing proportion of HIV diagnoses are being made outside of sexual health clinics, which is in line with evolving HIV testing guidelines. The HIV Medicine study revealed that […]Continue Reading ...
This protein structure diagram illustrates the location of the fusion peptide epitope (red) on the HIV spike (green), which projects out of the viral membrane (grey). The diagram also shows how a broadly neutralizing antibody (yellow) binds to the fusion peptide. Credit: NIAID An experimental vaccine regimen based on the structure of a vulnerable site […]Continue Reading ...
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