(HealthDay)—For the first time, a highly influential panel of experts says doctors should offer a daily pill to prevent HIV transmission to people who are at high risk for infection with the AIDS-causing virus. This treatment is called pre-exposure prophylaxis—PrEP for short—and it has been shown to be highly effective at preventing HIV’s spread, concluded […]Continue Reading ...
More than a year after a groundbreaking liver transplant doctors still can’t say if the recipient is HIV-positive or not. Credit: Shutterstock A lifesaving partial liver transplant from an HIV-infected mother to her uninfected child – the first of its kind – was conducted last year at the University of the Witwatersrand’s Donald Gordon Medical […]Continue Reading ...
Credit: CC0 Public Domain Researchers at Johns Hopkins have identified two patients with HIV whose immune cells behave differently than others with the virus and actually appear to help control viral load even years after infection. Moreover, both patients carry large amounts of virus in infected cells, but show no viral load in blood tests. […]Continue Reading ...
This graphic shows a modified HIV Env trimer (yellow) bound by neutralizing antibodies (left) and multiple modified HIV Env trimers (yellow) displayed on nanoparticle (blue) to mimic whole virus (right). Credit: Jiang Zhu/Scripps Research A new candidate HIV vaccine from Scripps Research surmounts technical hurdles that stymied previous vaccine efforts, and stimulates a powerful anti-HIV […]Continue Reading ...
Credit: CC0 Public Domain The abundance of personal smartphones in southern African countries got University of Washington professor Sarah Gimbel thinking: What if these phones were used by front-line health workers—namely nurses—to collect and analyze data on patients living with HIV or AIDS to improve their care? Gimbel, an implementation scientist at the UW School […]Continue Reading ...
Peer leader speaks to the sex worker community at the annual Baraza (community meeting) in Nairobi, Kenya. Credit: Julie Lajoie, Author provided With nearly two million new infections and one million associated deaths each year, the HIV (human immunodeficiency virus) pandemic is alive and well. Thirty-seven million people are now living with HIV, more than […]Continue Reading ...
Scanning electron micrograph of HIV-1 budding (in green) from cultured lymphocyte. This image has been colored to highlight important features; see PHIL 1197 for original black and white view of this image. Multiple round bumps on cell surface represent sites of assembly and budding of virions. Credit: CDC / C. Goldsmith, P. Feorino, E. L. […]Continue Reading ...
The WHO recommends HIV viral load testing to monitor people on ARVs. Credit: Shutterstock A United Nations initiative backed by global experts has set its sights on an ambitious programme to bring an end to the AIDS epidemic by 2030. The 90-90-90 strategy aims to do this by reaching three targets: 90% of all people […]Continue Reading ...
HIV infecting a human cell. Credit: NIH A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy (ART) originated from cellular proliferation, not viral replication, according to new research published in Nature Communications. Reducing the population size of this “reservoir” of infected cells represents the largest challenge for cure […]Continue Reading ...
The cone-shaped HIV capsid (left) is made up of capsid, or CA, proteins (right). Those proteins assemble into five-sided pentamers and six-sided hexamers to form the lattice-like structure of the protective capsid. Credit: University of Delaware HIV, the virus that causes AIDS, has been studied extensively ever since the AIDS epidemic was officially recognized by […]Continue Reading ...
HIV infecting a human cell. Credit: NIH The management of human immunodeficiency virus 1 (HIV), an autoimmune disorder that cripples the immune system by attacking healthy cells, remains a major global health challenge in developing countries that lack infrastructure and trained medical professionals. Investigators from Brigham and Women’s Hospital have designed a portable and affordable […]Continue Reading ...
HIV infecting a human cell. Credit: NIH A study published in The Lancet HIV shows that HIV-2 is more pathogenic than previously demonstrated. The new findings indicate that early treatment should be applied to all patients with HIV, not only to those with HIV-1. “The study is unique in that we have followed cohort of […]Continue Reading ...
Credit: CC0 Public Domain A persistent challenge in HIV/AIDS treatment and prevention is medication adherence – getting patients to take their medication as required to get the best results. Currently, a once-daily pill to prevent HIV infection is available. However, adherence to a once-daily regimen can be difficult for some people. Researchers from the UNC […]Continue Reading ...
Credit: CC0 Public Domain An international team that includes Rutgers scientists has made significant progress in developing a urine diagnostic test that can quickly, easily and inexpensively identify tuberculosis infection in people also infected with HIV. TB is the leading infectious disease killer in the world and the most common cause of death for people […]Continue Reading ...
Credit: CC0 Public Domain Research has shown that drug and alcohol use interferes with anti-retroviral medication adherence among gay and bisexual men (GBM) living with HIV. There is limited parallel examination of whether the same holds true for pre-exposure prophylaxis (PrEP) adherence among HIV-negative GBM. In a study published this month in the journal AIDS […]Continue Reading ...
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