Credit: Wikipedia / CC-BY-SA-3.0-de Inflammation can be good. It’s part of the body’s innate immune system, our first line of defense against illness and injury. However, if the inflammatory response goes on for too long, it can lead to a condition called chronic inflammation, where the body essentially attacks itself, wreaking biological havoc on our […]Continue Reading ...
A microscopic image of gastric cancer cells (magenta), with dividing cells shown in green. Credit: Jun Low/Walter and Eliza Hall Institute. Melbourne researchers have made the surprise discovery that the ‘odd one out’ in a family of proteins known to drive cancer development is instead critical for preventing stomach cancers. The research team showed switching […]Continue Reading ...
(The researchers from left to right) Adam Getzler, Huitian Diao, Dapeng Wang and Matthew Pipkin led the study on the Florida campus of The Scripps Research Institute. Credit: Scott Wiseman/The Scripps Research Institute Memory T cells are a critical element of our immune system’s historical archive. To prevent repeat infections, these cells retain a record […]Continue Reading ...
One day after head injury (left), bright dye along the edge of the brain suggests damage to the meninges, or the brain’s protective lining. After 35 days (right), the dye no longer appears, indicating the meninges may have healed. Credit: Larry Latour, Ph.D., National Institute of Neurological Disorders and Stroke. Following head injury, the protective […]Continue Reading ...
Credit: CC0 Public Domain Biological sex differences can have far-reaching, clinical consequences, as illustrated by organ transplant outcomes. Men and women who receive donated organs can have different rates of transplant rejection, in some cases influenced by the sex of the donor. In general, the influence of biological sex on transplant outcomes has not been […]Continue Reading ...
Credit: University of Reading Elderly people who find their annual flu shot is not helping them beat the virus may be lacking in effective natural killer cells, according to new research. In a paper published in Frontiers in Immunology, a team from the University of Reading looked at levels of different types of natural killer […]Continue Reading ...
Scientists have discovered a new metabolic process in the body that can switch off inflammation. They have discovered that ‘itaconate’—a molecule derived from glucose—acts as a powerful off-switch for macrophages, which are the cells in the immune system that lie at the heart of many inflammatory diseases including arthritis, inflammatory bowel disease and heart disease. […]Continue Reading ...
Cross section of an aorta from a mouse that was fed a high-fat, high-cholesterol diet, which accelerates the build-up of plaque. The large red plaque on the inside of the aorta was labeled with oil based stain, which highlights lipids. Credit: Dr. Dalia Gaddis, La Jolla Institute for Allergy and Immunology New research from scientists […]Continue Reading ...
Assistant Professor Maximiliano D’Angelo, Ph.D. Credit: Sanford Burnham Prebys Medical Discovery Institute (SBP) Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus—they play an essential role in the survival of T cells. A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers […]Continue Reading ...
From left to right Monash Biomedicine Discovery Institute’s Dr Jiyoti Verma, Associate Professor Ana Traven, Dr Thomas Naderer and Dr Tim Tucey. Credit: Steve Morton, Monash University A multidisciplinary study by Monash University Biomedicine Discovery Institute (BDI) researchers has revealed that a lethal fungus destroys the immune cell that would ordinarily kill it by stealing […]Continue Reading ...
Credit: Medical University of Vienna Whether or not you develop an allergy is largely dependent upon genetic factors. This is the main finding of a study recently published in EBioMedicine, just in time for World Allergy Week. The study was supervision of Winfried F. Pickl from MedUni Vienna’s Institute of Immunology. The Vienna researchers were […]Continue Reading ...
Prevalence of specific allergies among food-allergic children. Credit: Northwestern University Once upon a time, kids could bring candy to school for Halloween, and the market for trading lunchbox goodies was hot. These days, classrooms are peanut-free zones, and many schools ban treats altogether. That’s a direct response to a surge in childhood food allergies across […]Continue Reading ...
A conceptual illustration of how a protein can adopt different conformations upon mutation. The colored landscape represents the protein’s free energy, from high stability (yellow-green) to low (red). The all-atom details on the ribbon models depict mutated protein residues. Credit: Cecilia Clementi, Rice University For years, computational biologists have sought ways to model how proteins […]Continue Reading ...
Credit: CC0 Public Domain Long-term exposure to high levels of road traffic and ozone significantly increases the risk of asthma symptoms, asthma attacks or the need for use of asthma medications, according to a new study published in the European Respiratory Journal. The study strengthens the evidence on the link between long-term exposure to outdoor […]Continue Reading ...
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