Fluorescent microscopy image showing accumulation of phosphatidylethanolamine (PE, red) in human dendritic cells treated with synthetic F. tularensis PE containing liposomes. Blue indicates the cell nucleus. Credit: NIAID National Institutes of Health researchers have identified a naturally occurring lipid—a waxy, fatty acid—used by a disease-causing bacterium to impair the host immune response and increase the […]Continue Reading ...
Every year, Americans make 30,000 emergency room visits because of food allergies, according to the Food and Drug Administration. Even touching a surface that previously held peanuts can trigger anaphylaxis, a life-threatening allergic reaction. When a peanut-allergic person starts feeling their throat close up, they stab themselves with an epinephrine, or adrenaline, device and then […]Continue Reading ...
Mario Brameshuber, Benedikt Rossboth, Florian Baumgart and Gerhard Schütz (left to right). Credit: TU Wien Without T cells, we could not survive. They are a key component of the immune system and have highly sensitive receptors on their surface that can detect pathogens. The exact way that these receptors are distributed over the surface of […]Continue Reading ...
TORC1 contributes to aging in all species. Credit: resTORbio A team of researchers affiliated with Novartis Institutes for Biomedical Research and Biometrics Matters Limited, has found via testing with volunteers that TORC1 inhibitors can boost the immune system in the elderly. In their paper published in the journal Science Translational Medicine, the group describes the […]Continue Reading ...
Although about 10 percent of school-aged children in the United States have asthma, there are few comprehensive U.S. guidelines for treating pediatric asthma. The Pediatric Asthma Yardstick, a new guideline from the American College of Allergy, Asthma and Immunology (ACAAI), offers a user-friendly “operational document”. It helps health care professionals understand which controller treatments are […]Continue Reading ...
One of the most important cell types for controlling certain viral infections are natural killer (NK) cells. As part of the innate and rapid immune response, NK-cell recruitment and activation was thought to be a straightforward process. New research shows that NK-cell recruitment and activation requires a rather carefully choreographed interaction of three cell types […]Continue Reading ...
Polymorphic nuclear leukocytes infected with Chlamydia (blue). Credit: Karthika Rajeeve When chlamydia attacks the human body, the immune system activates. But the bacteria are adapted to defend themselves. Scientists from Würzburg have deciphered new details of their strategy. Chlamydia trachomatis is a common sexually transmitted disease. More than 131 million people are infected with this […]Continue Reading ...
(HealthDay)—Trauma or intense stress may up your odds of developing an autoimmune disease, a new study suggests. Comparing more than 106,000 people who had stress disorders with more than 1 million people without them, researchers found that stress was tied to a 36 percent greater risk of developing 41 autoimmune diseases, including rheumatoid arthritis, psoriasis, […]Continue Reading ...
Artistic rendering of the surface of a human dendritic cell, one of the cells of the innate immune system. Credit: National Institutes of Health EPFL scientists have discovered two small-molecule compound series that can effectively block a central pathway of the innate immune system, offering a promising new way for treating autoinflammatory diseases. The study […]Continue Reading ...
The C6orf106 or ‘C6’ gene. Credit: CSIRO Australia’s national science agency CSIRO has identified a new gene that plays a critical role in regulating the body’s immune response to infection and disease. The discovery could lead to the development of new treatments for influenza, arthritis and even cancer. The gene, called C6orf106 or “C6”, controls […]Continue Reading ...
Washington University researchers have found that immune cells called macrophages can trigger smooth muscle contractions in the intestinal tract, independent of nerve cells. The research in mice suggests that targeting a receptor (green) on macrophages (red) holds potential for treating chemotherapy-induced diarrhea. Credit: Center for the Study of Itch Some 50 to 80 percent of […]Continue Reading ...
‘Timer’ protein fluorescence across time. Credit: Imperial College London Scientists are unveiling how our immune system works – and malfunctions – thanks to an innovative technology that tracks immune cells. The technology has already been used to look at immune cells involved in a mouse model of multiple sclerosis, and could provide valuable insights into […]Continue Reading ...
Lars Bode, Ph.D., associate professor of pediatrics at UC San Diego School of Medicine. Credit: Erik Jepsen, UC San Diego The unique composition of a mother’s breastmilk may help to reduce food sensitization in her infant, report researchers at the University of California San Diego School of Medicine with colleagues in Canada. The findings, publishing […]Continue Reading ...
Nucleoside transporters. Credit: mdpi.com The immune system is host to a bewildering array of cell types. Traditionally, immunologists have classified cells in different states of activation according to the various interleukins, interferons and other cytokines they express or secrete. Unfortunately, this ever-sprawling matrix of cell markers has become a matrix of exceptions that is rapidly […]Continue Reading ...
An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/Wikipedia Recent research from Houston Methodist Hospital showed that a new immunotherapy was safe for patients with ALS and also revealed surprising results that could bring […]Continue Reading ...
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