A team of researchers led by Jonathan Stamler, MD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center, has discovered a pathway for enhancing the self-repair efforts of injured kidneys. The finding may pave the way for new drugs to stop or even reverse the progression of serious kidney disease […]Continue Reading ...
Credit: CC0 Public Domain Mice represent well over half of the non-human subjects of biomedical research, and the vast majority of those mice are inbred. Formed by generation after generation of mating between brothers and sisters, inbred mice are genetically identical to each other, like twins or clones. Inbreeding is well known to reduce health […]Continue Reading ...
Credit: NASA Research examining pressure on surgical units in sub-Saharan African countries estimates nearly 300 million people have a need for surgery in the region, placing a heavy burden on hospitals. The study by researchers from the United Nations Population Fund (UNFPA), WorldPop at the University of Southampton, the Technical University of Munich, Kenya Medical […]Continue Reading ...
Axons of retinal ganglion cells (red) derived from human pluripotent stem cells bundle together and navigate their environment using growth cones (green), similar to human development of the optic nerve. Credit: Department of Biology, School of Science at IUPUI IUPUI biologists are growing ‘mini retinas’ in the lab from stem cells to mimic the growth […]Continue Reading ...
Almost everything we do incorporates rhythm. At the University of Oslo 50 researchers from all over the world will provide us with some new answers about the meaning of rhythm for people – and possibly also develop the world’s best dancing robot. “If we can understand more about rhythm, we will understand more about how […]Continue Reading ...
Credit: CC0 Public Domain A material based on a natural product of bones and citrus fruit, called citrate, provides the extra energy that stem cells need to form new bone tissue, according to a team of Penn State bioengineers. Their new understanding of the mechanism that allows citrate to aid in bone regeneration will help […]Continue Reading ...
CRISPR (= Clustered Regularly Interspaced Short Palindromic Repeats) + DNA fragment, E.Coli. Credit: Mulepati, S., Bailey, S.; Astrojan/Wikipedia/ CC BY 3.0 Scientists at the RIKEN Center for Brain Science (CBS) in Japan have discovered how mutations related to a group of movement disorders produce their effects. Published in Proceedings of the National Academy of Sciences, […]Continue Reading ...
Comparison of the abundance of several species between the I/R-injured and the sham-operated mice at pre-I/R and days 2 and 10. Credit: Kanazawa University Gut microbiota-derived metabolites play important roles in health and disease. In this study, we show the pathophysiological role of D-serine in association with the gut microbiota in humans and mice with […]Continue Reading ...
Credit: CC0 Public Domain Researchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone that can be used to treat osteoarthritis. The bi-functional composite imitates the complex osteochondral structure of a joint, i.e. both cartilage and bone tissues. According to the World Health Organisation, around 10 percent […]Continue Reading ...
High magnification micrograph of hypertrophic decidual vasculopathy, as seen in pregnancy-induced hypertension. Credit: Wikipedia A collaboration of scientists from the University of Massachusetts Medical School, Beth Israel Deaconess Medical Center and Western Sydney University, have shown that an innovative new type of therapy using small interfering RNAs (siRNA) can temper the symptoms of preeclampsia in […]Continue Reading ...
Common bacteria that cause foodborne diseases are resistant to antibiotics used to treat infections, according to research that identified 39 genes responsible for this resistance. Credit: Rocky Mountain Laboratories / NIAID / NIH) Brazil’s Ministry of Health received reports of 11,524 outbreaks of foodborne diseases between 2000 and 2015, with 219,909 individuals falling sick and […]Continue Reading ...
Wildtype lens development (top) compared to the VPS45 mutant (bottom). Fiber cell differentiation is indicated in green. Credit: OIST How different cells in a multicellular organism acquire their identities remains a fundamental mystery of development. In the eye, for example, the lens contains two cell types—lens epithelial cells and lens fiber cells—the first of which […]Continue Reading ...
Skeletal muscle tissue. Credit: University of Michigan Medical School All vertebrates need muscles to function; they are the most abundant tissue in the human body and are integral to movement. In a recent article published in Nature Communications, an international team of researchers discovered two proteins essential to the development of skeletal muscle. This research, […]Continue Reading ...
After targeting the “motors” that generate forces in cancer cells to move, the cancer cells switch to a dendritic or “flowing” response to follow pathways in tumors that drive cell migration and promote spreading of the cancer. Credit: Tabdanov/Provenzano, University of Minnesota A new study by University of Minnesota biomedical engineers shows how they stopped […]Continue Reading ...
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