At right, a close-up of mouse brain tissue shows an engineered protein (stained green) being expressed by astrocytes, but no other cells. UCLA scientists used this technique to selectively silence astrocytes to explore their roles in mouse behavior. Credit: UCLA Health Repetitive behavior disorders are relatively common. One of the best known in this family […]Continue Reading ...
Credit: CC0 Public Domain Older adults fitted with a cochlear implant to compensate for severe hearing loss have significantly poorer cognitive function than their normal-hearing counterparts, reveals a new study. Hearing loss is a risk factor for cognitive decline and dementia, so this new finding suggests cochlear implants cannot fully compensate for this deterioration in […]Continue Reading ...
The ganglion cell layer of the retina is labelled with red to show the presence of a cell sensitive to motion in the upward direction. In low light, these cells become generalists to help the retina pick up the faintest signals of any kind of motion. Credit: Xiaoyang Yao, Duke University and Amanda J. McLaughlin […]Continue Reading ...
In multiple sclerosis, the immune system attacks the myelin sheaths of the nerve fibres (white). Credit: Ralwel/iStockphoto A team of researchers from the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis it is not only specific T cells that cause inflammation and lesions in the brain. B cells, a […]Continue Reading ...
In this March 23, 2017 photo provided by the Sunnybrook Health Sciences Centre, patient Rick Karr is prepared for treatment at the facility in Toronto, Canada. Karr was the first Alzheimer’s patient treated with focused ultrasound to open the blood-brain barrier. Scientists are using ultrasound waves to temporarily jiggle an opening in the brain’s protective […]Continue Reading ...
Generalized 3 Hz spike and wave discharges in a child with childhood absence epilepsy. Credit: Wikipedia. Heartbeat irregularities connected to brain activity abnormalities may lead to the ability to predict eventual epileptic seizures in subjects who suffered physical or infectious brain insults, according to Penn State researchers who studied mouse models of cerebral malaria, which […]Continue Reading ...
Credit: CC0 Public Domain Take a look at your favorite mug; it probably looks the same as it always has, but your neurons may not think so. Neurons are firing in response to the visual stimuli they see but they don’t fire in exactly the same way every time. Researchers at Baylor College of Medicine […]Continue Reading ...
Methamphetamine (“meth,” left) is known to disrupt the tight junctions – shown here in green – between the cells of the blood-brain barrier (BBB), letting toxic substances enter the brain. When the researchers added meth to healthy BBB cells (middle), it caused the junctions to become leaky (right), confirming that the BBB-Brain Chip system can […]Continue Reading ...
A pile of cocaine hydrochloride. Credit: DEA Drug Enforcement Agency, public domain A study in cocaine-addicted rats reports long-lasting increases in the number of neurons that produce orexin—a chemical messenger important for sleep and appetite—that may be at the root of the addiction. The study, performed by researchers at Rutgers University, New Jersey, was published […]Continue Reading ...
Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Tremor, rigidity and bradykinesia are well known symptoms of Parkinson’s disease, occurring in different combinations in individual patients. However, there have not been any neuronal components that definitively identify the main symptom groupings – including […]Continue Reading ...
New evidence-based guidelines, developed by the Centers for Disease Control and Prevention (CDC) with input from the American College of Emergency Physicians (ACEP) and others put forward recommendations for a broad range of health care providers responsible for detection and management of pediatric mild traumatic brain injury, most of which are concussions. The CDC recommendations […]Continue Reading ...
Farah Lubin. Credit: UAB Understanding how memories form and are retrieved has applications to psychiatric, neurological and neurodegenerative disorders, and may be helpful to attenuate maladaptive memories in psychiatric disorders. Two broad findings have been seen in memory reconsolidation, which is the retrieval and strengthening of a recent memory. The first broad finding is that, […]Continue Reading ...
Scientists have discovered a new way to organize odor molecules based on how often they occur together in nature, and to map this data to discover regions of odor combinations humans find most pleasurable. From left: Yuansheng Zhou and Tatyana Sharpee. Credit: Salk Institute Every smell, from a rose to a smoky fire to a […]Continue Reading ...
STRASBURG, PA- A new report has identified an alternative method to deliver nusinersen to patients with spinal muscular atrophy (SMA) using a subcutaneous intrathecal catheter system (SIC) configured by connecting an intrathecal catheter to an implantable infusion port. SMA is a devastating genetic disease that leads to progressive degeneration of motor neurons that control movement, […]Continue Reading ...
Credit: Gabriella Panuccio At the border between regenerative medicine and neural engineering lies enhanced regenerative medicine. Using brain tissue modulated by electronic components, EU research has tackled the most common form of epilepsy. Temporal lobe epilepsy (TLE) is the most common form of epilepsy and yet, the most unresponsive to treatment. Patients have a typical […]Continue Reading ...
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