August 13, 2018 Autophagy is a process of destruction and processing of damaged cell components by the cells themselves. It is used by a cell to clean itself of excessive organelles and sometimes for self-execution. This adaptive mechanism supports a healthy phenotype on the cellular level. Autophagy is activated in certain cases of acute kidney […]Continue Reading ...
June 28, 2018 A study led by Luísa Lopes, Group Leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and published today in the prestigious journal Molecular Psychiatry, describes a new mechanism involved in memory loss associated with aging. The work developed over 3 years by a team of Portuguese, French and German […]Continue Reading ...
May 11, 2018 A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism. The study shows that an increasingly deteriorating communication between the cells’ organelles is an important cause of aging. The discovery is the result of a collaboration between five research groups at the […]Continue Reading ...
April 11, 2018 For 93-year-old Joseph Brown, the clearest sign of aging was his inability the other day to remember he had to have his pants unzipped to pull them on. For 95-year-old Caroline Mayer, it was deciding at age 80 to put away her skis, after two hip replacements. And for 56-year-old Dr. Thomas […]Continue Reading ...
April 6, 2018 Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized […]Continue Reading ...
Dena Dubal (center), MD, PhD, and her team have jumped head first into studying aging and neurodegenerative disease through their research into a protein called klotho. Credit: Steve Babuljak Neurologist and neuroscientist Dena Dubal, MD, Ph.D., is taking an innovative approach to battling neurodegenerative diseases like Alzheimer’s disease and dementia. Rather than trying to understand […]Continue Reading ...
March 22, 2018 We are as old as our arteries, the adage goes, so could reversing the aging of blood vessels hold the key to restoring youthful vitality? The answer appears to be yes, at least in mice, according to a new study led by investigators at Harvard Medical School. The research, published March 22 […]Continue Reading ...
March 20, 2018 In a recent paper published in Cell Reports, Saint Louis University researchers have uncovered new answers about why cells rapidly age in children with a rare and fatal disease. The data points to cellular replication stress and a mistaken innate immune response as culprits, and the team found success in the laboratory […]Continue Reading ...
The C/EBPß-LIP gene regulator is involved in the aging process. If LIP is missing, the lifespan of mice increases and physical fitness is maintained during aging; without a calorie restriction. Credit: Kerstin Wagner / FLI Aging is a major risk factor for physical frailty and the development of age-related diseases such as cancer, cardiovascular diseases, […]Continue Reading ...
April 28, 2018 Insilico Medicine, a Baltimore-based company specializing in the application of next-generation artificial intelligence for drug discovery, biomarker development and aging research, announces the presentation of its CEO, Alex Zhavoronkov, at the Pioneers 18 Conference, May 25, 2018, Vienna, Austria. Dr. Zhavoronkov’s session “Artificial Intelligence for Aging Research” will be devoted to the […]Continue Reading ...
April 5, 2018 Conflict, a death in the family, financial hardship and serious medical crises are all associated with accelerated physical aging. In a new study, researchers at the University of California San Diego School of Medicine found that such negative fateful life events — or FLEs — appear to also specifically accelerate aging in […]Continue Reading ...
March 29, 2018 Researchers from UT Southwestern’s Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Internal Medicine’s Division of Nephrology recently published work in Nature that reveals the molecular structure of the so-called “anti-aging” protein alpha Klotho (a-Klotho) and how it transmits a hormonal signal that controls a variety of biologic […]Continue Reading ...
Coronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of human brain indicating The lab of Shelley Berger, PhD, Perelman School of Medicine, University of Pennsylvania Although certain genetic variants increase the risk of Alzheimer’s disease (AD), age is the strongest known risk factor. But […]Continue Reading ...
By Dr Ananya Mandal, MDMarch 23, 2018 According to a new study from the researchers at Harvard Medical School and the University of New South Wales, the actually cellular processes that cause aging of the blood vessels have been understood. Dr. David Sinclair senior investigator, a professor and co-director of the Paul F. Glenn Center […]Continue Reading ...
March 16, 2018 Americans may be aging more slowly than they were two decades ago. A new study by University of Southern California and Yale University researchers suggests that at least part of the gains in life expectancy over recent decades may be due to a change in the rate of biological aging, rather than […]Continue Reading ...
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