Illustration showing tightening of gut barrier cells and reduced inflammation due to UroA Credit: Praveen Kumar Vemula, Ph.D., Institute for Stem Cell Biology and Regenerative Medicine, India, and Venkatakrishna Jala, Ph.D., UofL Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, […]Continue Reading ...
Millions of people suffer from inflammatory bowel disease (IBD) worldwide, either in the form of ulcerative colitis or Crohn’s disease, and few effective long-term treatments are available. Chronic intestinal inflammation is a hallmark of IBD. The gut barrier is a single-cell epithelial layer that provides protection against antigens and toxins present in the gut. Gut […]Continue Reading ...
In the human brain, nerve cells – so-called neurons – care for the transmission of electrical signals. They form the functional component responsible for sensations, stimuli and memories. In the presence of dementia, there is an adsorption of proteins outside the neurons, which then leads to the death of the neuronal cells. How to prevent […]Continue Reading ...
In this March 23, 2017 photo provided by the Sunnybrook Health Sciences Centre, patient Rick Karr is prepared for treatment at the facility in Toronto, Canada. Karr was the first Alzheimer’s patient treated with focused ultrasound to open the blood-brain barrier. Scientists are using ultrasound waves to temporarily jiggle an opening in the brain’s protective […]Continue Reading ...
August 15, 2018 The blood-brain barrier is a specialized network of vascular and brain cells that acts as the brain’s security system, helping to safeguard the brain and regulate the flow of substances into and out of it. While this network protects the brain, it also limits doctors’ ability to deliver effective doses of disease-fighting […]Continue Reading ...
August 1, 2018 More than one in 10 babies worldwide are born prematurely, according to the World Health Organization. Now scientists report in ACS Biomaterials Science & Engineering that they have developed an organ-on-a-chip that could help explain why. The device, which replicates the functions of a key membrane in the placenta, could lead to […]Continue Reading ...
New findings from the University of Kentucky published in the Journal of Neuroscience demonstrate that there may be ways to address blood-brain barrier dysfunction in epilepsy. Epilepsy is one of the most common neurological disorders and around one-third of epilepsy patients do not respond well to anti-seizure drugs. Until now, it was believed that the […]Continue Reading ...
September 19, 2017 Scientists have helped supply a approach to higher know the way to permit medication to go into the mind and the way most cancers cells make it previous the blood mind barrier. The mind is safe by way of the near-impermeable blood mind barrier, a citadel which protects the mind however which […]Continue Reading ...
The first study investigating the mechanism of how a disease develops using human organ-on-a-chip technology has been successfully completed by engineers at The University of Texas at Austin. Researchers from the Cockrell School of Engineering were able to shed light on a part of the human body – the digestive system — where many questions […]Continue Reading ...
Credit: CC0 Public Domain Similar to patients with Crohn’s disease, elderly people with stomach problems have a intestinal barrier that is not functioning optimally. However, fibre can strengthen the intestinal barrier and thus, counteract gastrointestinal problems. This is shown in John-Peter Ganda Mall’s thesis in biomedicine at Örebro University. The function of the intestinal barrier […]Continue Reading ...
Similar to patients with Crohn’s disease, elderly people with stomach problems have a intestinal barrier that is not functioning optimally. However, fiber can strengthen the intestinal barrier and thus, counteract gastrointestinal problems. This is shown in John-Peter Ganda Mall’s thesis in biomedicine at örebro University. The function of the intestinal barrier can be compared to […]Continue Reading ...
August 10, 2018 In the first such clinical trial in the United States, physician-scientists with the University of Maryland School of Medicine (UMSOM) are investigating the use of MRI-guided focused ultrasound to open the blood-brain barrier. The trial will be conducted with patients undergoing brain cancer surgery at the University of Maryland Medical Center (UMMC). […]Continue Reading ...
May 30, 2018 Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have developed a 3D brain organoid that could have potential applications in drug discovery and disease modeling. This is the first engineered tissue equivalent to closely resemble normal human brain anatomy, containing all six major cell types found in normal organs including, neurons and […]Continue Reading ...
September 22, 2017 Exhausting water damages our protecting pores and skin barrier and may give a contribution to the improvement of eczema, a brand new find out about has proven. Researchers from the College of Sheffield and King’s Faculty London have came upon that exposing the surface to laborious water damages the surface barrier – […]Continue Reading ...
Empa’s multicellular type, which is mimicking the placental barrier: a core of connective tissue cells, surrounded via trophoblast cells. Credit score: Empa An Empa group has succeeded in creating a brand new 3-dimensional cellular type of the human placental barrier. The “type organ” can briefly and reliably ship new data at the consumption of gear, […]Continue Reading ...
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