Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Scientists have gained clues into how a Parkinson’s disease treatment, called deep brain stimulation, helps tackle symptoms. The early-stage study, by researchers at Imperial College London, suggests the treatment boosts the number and strength of […]Continue Reading ...
In response to continuous optogenetic stimulation to their striatal output neurons, mice turned in one direction, as is typical of mouse models of Parkinson’s disease. When exposed to pulsed stimulation, the animal’s brain activity normalized and they turned the opposite direction. Credit: Okinawa Institute of Science and Technology The tell-tale tremors of Parkinson’s disease emerge […]Continue Reading ...
Credit: CC0 Public Domain The amygdala—a region of the brain known to be involved in emotions and social behaviors—has been found to play a critical role in the regulation of parenting behavior, according to a new study by UCLA researchers. Differences in this brain region between males and females help to explain why the two […]Continue Reading ...
Mar 12 2019 Discarding information from the brain is associated with more mental effort than keeping it, finds a human neuroimaging study published in JNeurosci. These results suggest moderately reactivating the memory of an unwanted experience may be required to forget it. Although the human brain automatically remembers and forgets information, these processes can also […]Continue Reading ...
Major depressive disorder is a debilitating illness that affects more than 350 million people around the world. The most common treatments for depression are Selective Serotonin Reuptake Inhibitors (SSRIs), drugs such as Prozac that increase serotonin levels in some regions of the brain. About half of the patients who take the pills, however, do not […]Continue Reading ...
It’s been estimated that the human brain contains roughly 100 billion neurons, together completing countless tasks through countless connections. So how do we make sense of the roles each of these neurons play? As part of the United States BRAIN Initiative, scientists from Cold Spring Harbor Laboratory (CSHL) have outlined a way to classify neurons […]Continue Reading ...
In a study published today in the Journal of Experimental Medicine, researchers successfully used a new approach that significantly minimized brain damage caused by stroke in mouse models. The new approach works by targeting hemichannels—pathways that allow for the flow of chemical ions and small molecules—that are expressed by astrocytes, cells that play a protective […]Continue Reading ...
What are concussion tests? Concussion tests can help find out if you or your child has suffered a concussion. A concussion is a type of brain injury caused by a bump, blow, or jolt to the head. Young children are at a higher risk of concussions because they are more active and because their brains […]Continue Reading ...
Elderly people with high blood pressure, or hypertension, who took medicine to keep their 24-hour systolic blood pressure around 130 mm Hg for three years showed significantly less accumulation of harmful brain lesions compared with those taking medicine to maintain a systolic blood pressure around 145 mm Hg, according to research presented at the American […]Continue Reading ...
The hippocampus of a female mouse that has been genetically engineered to overproduce TIA1 protein. (The green color indicates neurons that produce excess TIA1, while the blue color lights up the nucleus of each cell to permit easier visualization of cells within the tissue). Increased levels of TIA1 protein lead to heightened activity of immune […]Continue Reading ...
Some electrical engineers design the giant dynamos and transmission lines that power society. Others apply their prowess to electronics in cars and televisions, or — still smaller — the microprocessors in phones and watches. Montana State University’s Anja Kunze, assistant professor in the Department of Electrical and Computer Engineering, studies the tiny electrochemical signals that […]Continue Reading ...
The drugs statins, which are used to prevent cardiovascular diseases, also guard against brain hemorrhages. This is the conclusion of most extensive study ever carried out, which thus also rebuffs suspicions of the opposite being true. As well as lowering blood cholesterol, the medication statin also acts to guard against hemorrhages. This is shown by […]Continue Reading ...
Choosing to forget something might take more mental effort than trying to remember it, researchers at The University of Texas at Austin discovered through neuroimaging. These findings, published in the Journal of Neuroscience, suggest that in order to forget an unwanted experience, more attention should be focused on it. This surprising result extends prior research […]Continue Reading ...
Concussion researchers have long suggested that damage to the corpus callosum, a thick bundle of nerves that connects the brain’s two halves, could result in some common side effects of concussion, like dizziness or vision problems. The assumption is straightforward – that damage to the corpus callosum could affect coordination between the two halves – […]Continue Reading ...
Brain cells, or gray matter, can be seen wrapping around the folds of the brain like a thin sheet. White matter, composing a large part of this image, connects brain cells and allows them to communicate. Credit: Children’s Hospital Los Angeles One in 59 children are diagnosed with an Autism Spectrum Disorder (ASD), a wide […]Continue Reading ...
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