A study by researchers at University of Colorado Cancer Center and Oregon Health & Science University published today in the Journal of the American Medical Association Network shows that breast cancers diagnosed in young women within 10 years of giving birth are more likely to metastasize, and thus more likely to cause death, than breast […]Continue Reading ...
A multicenter study from SWOG Cancer Research Network found that infections with hepatitis B and C are common in new cancer patients, but few of these patients are screened for the viruses.Continue Reading ...
Cancers most commonly arise because of a series of two to five mutations in different genes that combine to cause a tumor. Evidence from a growing number of experiments focused on truncal mutations–the first mutations in a given sequence–suggests a new direction in understanding the origins of cancer. In a paper published today in Cancer […]Continue Reading ...
Researchers at the University of Toronto have discovered mutational signatures of tumor hypoxia (low oxygen) in 19 cancer types. The results could be used to help clinicians identify patients who would benefit from higher treatment doses. m63085 | Shutterstock In a landmark pan-cancer study analyzing more than 8,000 tumors across 19 different cancer types, researchers […]Continue Reading ...
Skin cancer is on the rise in the United States. Squamous cell carcinoma, the second most common form of cancer in the U.S., has the highest mortality rate of all non-melanoma skin cancers. In roughly two to five percent of patients, the disease will metastasize and spread throughout the body, making it difficult to treat. […]Continue Reading ...
Two new mouse models of uterine cancer shed light on how this disease – the most common gynecological cancer in the U.S. – happens. Led by researchers at Baylor College of Medicine, the team of scientists found that the Transforming Growth Factor beta (TGF-beta) signaling pathway in uterine cells protects against the disease by suppressing […]Continue Reading ...
For cancer to spread, it needs a hospitable environment in distant organs. This fertile “soil” can provide a home to circulating malignant cells. Recent research has shown that cancer cells from the primary tumor can help ready this soil by sending out small vesicles. These vesicles contain a cocktail of molecules that “educate” healthy cells […]Continue Reading ...
ALAMEDA, Calif.–(BUSINESS WIRE)–Jan. 14, 2019– Exelixis, Inc. (NASDAQ:EXEL) today announced that the U.S. Food and Drug Administration (FDA) approved Cabometyx (cabozantinib) tablets for patients with hepatocellular carcinoma (HCC) who have been previously treated with sorafenib. HCC is the most common form of liver cancer and the fastest-rising cause of cancer-related death in the U.S.1 “This […]Continue Reading ...
A new report published today in JAMA Oncology describes alarmingly high rates of undiagnosed acute and chronic hepatitis B and hepatitis C in patients with cancer. These diseases could be seriously detrimental to treatment outcomes. vitstudio | Shutterstock Hepatitis B and hepatitis C are serious but treatable viral infections, which can have life-threatening complications. These […]Continue Reading ...
In the first effort to predict the future burden of colorectal cancer mortality globally, researchers note that colon and rectal cancer mortality rates are projected to decrease in most countries apart from some Latin American and Caribbean countries, but increases are predicted for several countries from Europe, North America and Oceania. The findings are published […]Continue Reading ...
A new study from a Massachusetts General Hospital (MGH) research team has found that the hypertension drug losartan, which targets the angiotensin signaling pathway, may improve the effectiveness of chemotherapy agents used to treat ovarian cancer. Previous research from the same team identified a similar effect for losartan in animal models of breast and pancreatic […]Continue Reading ...
Jan 16 2019 As cancer cells respond to cues in their microenvironment, they can enter a highly plastic state in which they are susceptible to transdifferentiation into a different type of cell. Researchers at the University of Basel in Switzerland exploited this critical phase, known as an epithelial-mesenchymal transition (EMT), to coax breast cancer cells […]Continue Reading ...
The University of Texas MD Anderson Cancer Center and Dragonfly Therapeutics, Inc., today announced a strategic collaboration to bring Dragonfly’s TriNKET™ (tri-specific natural killer cell engager therapy) immunotherapy drug candidates to patients in clinical trials beginning in 2019. Dragonfly committed more than $10 million to launch the studies, which will be available for patients with […]Continue Reading ...
Following up on a groundbreaking 2018 study in which BIDMC’s Dipak Panigrahy, MD, demonstrated that dead and dying cancer cells killed by conventional cancer treatments paradoxically trigger inflammation that promotes tumor growth and metastasis, a new study led by Allison Gartung, PhD, describes a novel approach to suppressing chemotherapy-induced tumor growth in an ovarian cancer […]Continue Reading ...
Scientists have created the most comprehensive method yet to predict a woman’s risk of breast cancer, according to a study by Cancer Research UK published in Genetics in Medicine. They have a developed a way of calculating the risk of developing the disease by combining information on family history and genetics with other factors such […]Continue Reading ...
- Breast cancers more likely to metastasize in young women within 10 years of giving birth
- Blood vessels can now be created perfectly in a petri dish
- Young-Onset Type 2 Diabetes Tied to Increased Hospitalization Risk
- For-profit nursing schools associated with lower performance on nurse licensure test
- Considering the culture of consent in medicine
- Researchers identify comprehensive guidelines for managing severe atopic dermatitis
- Analyzing proteins in blister fluid may classify burn severity more accurately
- Study finds higher suicide rates among youth who were Medicaid enrollees
- Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons
- New biodegradable wound dressing material accelerates healing
- Life in Space May Take Toll on Spinal Muscles
- Bulldogs’ screw tails linked to human genetic disease
- Immunotherapy target identified for pediatric cancers
- Financial stress may increase heart disease risk in African Americans
- Scientists solve another piece of Ebola virus puzzle
- New project finds how endocrine disruptors interfere with thyroid functions
- Research finds decline in ketone body utilization when coronary circulation is reduced
- Let’s map our DNA and save billions each year in health costs
- AI demonstrates potential to identify irregular heart rhythms as well as humans
- Study shows link between air pollution and increased risk of sleep apnea