Only cells expressing the HaloTag receptor can bind to the AMPA-repressing drug, ensuring virtually perfect cell-type specificity. Credit: Duke Research Blog The brain is the body’s most complex organ, and consequently the least understood. In fact, researchers like Michael Tadross, MD, PhD, wonder if the current research methods employed by neuroscientists are telling us as […]Continue Reading ...
Researchers at Carnegie Mellon University have found a new and efficient way to characterize cell types following single-cell RNA sequencing (scRNA-seq). ktsdesign | Shutterstock The new method involves the use of neural networks and supervised machine learning techniques rather than marker genes, which are not available for all cell types. Using this new, automated technique, […]Continue Reading ...
Researchers have developed a new technique to analyze cell membrane proteins in situ which could revolutionize the way in which we study diseases, such as cancer, metabolic and heart diseases. The discovery was made as part of an international research collaboration, led by Oxford University, alongside peers including Imperial College London. The technique could dramatically […]Continue Reading ...
The number of critically endangered animals has been increasing in recent years. According to data from the International Union for the Conservation of Nature (IUCN), 1375 avian species are categorized as being endangered animals, and around 12% of the endangered species are avian. The conservation of endangered species is an important task for our next […]Continue Reading ...
AMSBIO has expanded its range of high quality FFPE cancer cell line controls for immunohistochemistry (IHC), in situ hybridization (ISH) and Next Generation Sequencing (NGS) applications. Variations in FFPE tissue sample quality and experimental setup can lead to misleading results without reliable controls. Traditional cell or tissue-based control specimens often present intra specimen variation, lot-to-lot […]Continue Reading ...
Researchers have provided new insight on the mechanisms behind the development of clear cell Renal Cell Carcinoma (ccRCC), according to new findings published in eLife. The study in human cells and mice could have implications for how we understand and treat ccRCC – a major subtype of human kidney cancer. Kidney cancer is one of […]Continue Reading ...
Long thought to suppress cancer by slowing cellular metabolism, the protein complex AMPK also seemed to help some tumors grow, confounding researchers. Now, Salk Institute researchers have solved the long-standing mystery around why AMPK can both hinder and help cancer. The lab of Salk Professor Reuben Shaw showed that late-stage cancers can trigger AMPK’s cellular […]Continue Reading ...
A new immunotherapy screening prototype developed by University of California, Irvine researchers can quickly create individualized cancer treatments that will allow physicians to effectively target tumors without the side effects of standard cancer drugs. UCI’s Weian Zhao and Nobel laureate David Baltimore with Caltech led the research team that developed a tracking and screening system […]Continue Reading ...
UCLA biologists have discovered how head injuries adversely affect individual cells and genes that can lead to serious brain disorders. The life scientists provide the first cell “atlas” of the hippocampus — the part of the brain that helps regulate learning and memory — when it is affected by traumatic brain injury. The team also […]Continue Reading ...
BOTHELL, Wash.–(BUSINESS WIRE)–Nov. 16, 2018– Seattle Genetics, Inc. (Nasdaq:SGEN) today announced a new approval for Adcetris (brentuximab vedotin) in combination with CHP chemotherapy (cyclophosphamide, doxorubicin, prednisone) from the U.S. Food and Drug Administration (FDA) for adults with previously untreated systemic anaplastic large cell lymphoma (sALCL) or other CD30-expressing peripheral T-cell lymphomas (PTCL), including angioimmunoblastic T-cell […]Continue Reading ...
Scientists at the National Synchrotron Light Source II (NSLS-II)–a U.S. Department of Energy (DOE) Office of Science User Facility at DOE’s Brookhaven National Laboratory–have used ultrabright x-rays to image single bacteria with higher spatial resolution than ever before. Their work, published in Scientific Reports, demonstrates an x-ray imaging technique, called x-ray fluorescence microscopy (XRF), as […]Continue Reading ...
Researchers at Osaka University reveal the importance of a pathway in controlling the segregation of chromosomes when cells divide, which could be useful for treating a range of diseases associated with abnormal cell division When a cell divides—a process known as mitosis—its chromosomes need to be separated and evenly distributed into the newly created daughter […]Continue Reading ...
All vertebrates need muscles to function; they are the most abundant tissue in the human body and are integral to movement. In a recent article published in Nature Communications, an international team of researchers discovered two proteins essential to the development of skeletal muscle. This research, led by Jean-François Côté, a professor at the Montreal […]Continue Reading ...
Cell division is integral to understanding development, growth and disease states such as cancer. It has long been known that for replication, a complete new set of DNA and the formation of a septum, dividing the two cells, are necessary. New research changes perspectives of how these two processes influence the timing of cell division. […]Continue Reading ...
Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer’s and Parkinson’s diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries. Stem cell transplantation, which shows promise as a treatment for central nervous system diseases, has been hampered by low cell survival rates, […]Continue Reading ...
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