In any movie, the “self-destruct” button is usually the last resort, only opted for in the most dire of circumstances. But for a cell, pulling the plug on yourself can be more than an act of dramatic demise: Death is a sickly cell’s way of protecting the rest of the body from illness. In my […]Continue Reading ...
Mar 14 2019 Dolomite Bio is delighted to announce the launch of the game-changing Nadia single-cell platform, a groundbreaking system set to escalate scRNA-Seq to new heights, offering the fast-growing single-cell research sector an innovative solution for a wide range of potential applications. This novel product family will be on display from the 9th to […]Continue Reading ...
FUJIFILM Irvine Scientific, Inc., a world leader in the optimization and manufacture of cell culture media, today announced the introduction of IS Sf Insect medium. The serum-free, animal component-free, low hydrolysate medium is formulated for scalability for the consistent growth and yields of proteins, viral vectors and viral-like particles using baculovirus expression systems (BEVS), in […]Continue Reading ...
Metabolic changes in cells can occur at the earliest stages of disease. In most cases, knowledge of those signals is limited, since we usually detect disease only after it has done significant damage. Now, a team led by engineers at Tufts University School of Engineering has opened a window into the cell by developing an […]Continue Reading ...
Mar 14 2019 Dolomite Bio, part of the Blacktrace group, is helping to drive forward the single-cell genomics revolution. Single cell analysis promises to transform drug discovery and disease research, enabling scientists to investigate cell diversity and quantify gene expression at the cellular level. This up and coming market sector is forecast to be worth […]Continue Reading ...
In this interview, News-Medical speaks to Dr. Richard Eglen from Corning Life Sciences about the use of organoids in the drug discovery workflow, including the screening of candidate compounds for efficacy, toxicity, and pharmacokinetics. What are organoids and how are they used in drug discovery and preclinical development? Organoids are complex 3D cell structures that […]Continue Reading ...
A network of Setd5-mutant neuronal cultures extracted from the cortex of a mouse cortex. Cell nuclei are blue. Neurons are white. Astrocytes, a type of brain cell, are red. Credit: Alysson Muotri, UC San Diego The causes of autism spectrum disorder (ASD) are diverse and to some extent, unknown. But without doubt, they are complex, […]Continue Reading ...
Mar 8 2019 Researchers on the path to finding a cure for spina bifida have identified specific elements in stem cell secretions as key to protecting neurons and ultimately reducing the lower-limb paralysis associated with the birth defect. Those elements are exosomes — vesicles that transfer molecules from cell to cell — and a small […]Continue Reading ...
The identification of ORP2 as the protein responsible for transporting cholesterol around a cell opens the way to develop drugs that could improve the body’s good cholesterol levels. Credit: Shutterstock Scientists at UNSW Sydney have made a breakthrough discovery about cholesterol transportation in cells that opens the way for new drugs to increase the body’s […]Continue Reading ...
It has been known for decades that cancer cells have an altered metabolism and it is seen in several biochemical pathways and in particular, in the way they get energy for their survival. If healthy cells use the mitochondrial respiratory chain, tumors use aerobic glycolysis, a process that allows them taking energy quickly but depending […]Continue Reading ...
Cytochrome c is a small enzyme that plays an important role in the production of energy by mitochondria. It is also involved in signaling dangerous problems that warrant apoptosis, or programmed cell death. Using solid-state NMR, University of Groningen Associate Professor of Solid-State NMR Spectroscopy Patrick van der Wel and colleagues from the University of […]Continue Reading ...
In a new study, researchers at the University of Copenhagen show that the development of a certain type of immature stem cells – also known as progenitor cells – depends on the quantity of a special protein and interaction with other cells in the body. The new study has just been published in the scientific […]Continue Reading ...
Scientists have shed light on how healthy cells develop by identifying the role of key molecules involved. The components, known as R-loops, are formed during cell development and have been shown to play an important role in the process. The latest finding overturns previous thinking that R-loops, formed from the genetic material that makes up […]Continue Reading ...
Mar 8 2019 In diffuse cutaneous leishmanisis (DCL), a rare form of leishmaniasis, parasites grow uncontrolled in skin lesions across the body. For the first time, researchers reporting in PLOS Neglected Tropical Diseases have now profiled how the human immune system responds to a DCL infection and, in turn, how Leishmania amazonensis adapts to the […]Continue Reading ...
Influenza viruses from bats use an entirely different portal to enter the cell than all previously known types of influenza/human cells also infectable in the lab/publication in Nature Researchers from the Medical Center – University of Freiburg and the University of Zurich have discovered an entirely new infection route for influenza A viruses. While all […]Continue Reading ...
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