Mosaic of retinal pigment epithelial cells, visualized with indocyanine green (ICG) and adaptive optics. Credit: Johnny Tam, Ph.D., National Eye Institute Cells of the retinal pigment epithelium (RPE) form unique patterns that can be used to track changes in this important layer of tissue in the back of the eye, researchers at the National Eye […]Continue Reading ...
Credit: Michal Vitek/Shutterstock For every person in the world who receives a cornea transplant, there are 69 others who still need one. That leaves about 12.5m people with limited sight because there aren’t enough eye donors. But what if we could grow new corneas in the lab? Over the last decade, scientists have been testing […]Continue Reading ...
An international study led from Karolinska Institutet provides new insights into the regulatory T cells’ role in protecting against autoimmune disease. By mapping the targets of the immune system in patients with the rare disease IPEX, they were able to show that regulatory T cells control immunotolerance in the gut. The results are published in […]Continue Reading ...
Folk medicines and herbal products have been used for millennia to combat a whole range of ailments, at times to the chagrin of modern scientists who have struggled to explain their medicinal benefits. However a recent study by researchers at the University of Sydney has determined exactly how a popular ancient remedy, the elderberry fruit, […]Continue Reading ...
University of Alabama at Birmingham researchers will receive $17.8 million in federal funding to attack a key “knowledge gap” in human immunology — how the B cells and antibody-secreting cells that reside in tissues and organs differ from those found in blood. It is an exploration never undertaken in a systematic way, studying many individual […]Continue Reading ...
Scientists from Far Eastern Federal University (FEFU) in cooperation with colleagues from Blokhin Russian Cancer Research Center (Moscow), Switzerland, and Sweden for the first time studied proteins, which constitute WNT signaling pathway of the cancer stem cells of glioblastoma multiforme (GBM CD133+ CSCs), one of the most aggressive brain tumors. Researchers revealed a number of […]Continue Reading ...
Killer T cells surround a cancer cell. Credit: NIH Oral cancer is known for its high mortality rate in developing countries, but an international team of scientists hope its latest discovery will change that. Researchers from the University of Otago and the Indian Statistical Institute (ISI), Kolkata, have discovered epigenetic markers that are distinctly different […]Continue Reading ...
Researchers at the University of Zurich and from IBM Research have investigated the varying composition of cancer and immune cells in over one hundred breast tumors. They’ve found that aggressive tumors are often dominated by a single type of tumor cell. If certain immune cells are present as well, an immune therapy could be successful […]Continue Reading ...
Researchers have defined the roles of various cells in the bone marrow that are thought to control the fate of the nearly half million blood cells that develop there each day. Scientists at NYU School of Medicine behind the new work say little had been known about the fraction of cells examined in the study, […]Continue Reading ...
Credit: stock.adobe.com Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized molecular “clock” within cell populations. Much like human beings have circadian rhythms that affect sleepiness and wakefulness, […]Continue Reading ...
Credit: CC0 Public Domain New research from the University of Pittsburgh School of Medicine and the UPMC Hillman Cancer Center sheds light on how tumors use the body’s regulators of immunity for their own benefit. Published today in Nature Immunology, the findings could be used to develop the next generation of immune therapies to fight […]Continue Reading ...
Sometimes cells need to die. The process of cell death is encoded within the genome of all higher organisms to kill off cancerous cells, and as a normal part of development to shape a mass of embryonic cells into the organism it will become. Now Jefferson researchers show a gene called gasdermin E, which is […]Continue Reading ...
CRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0) In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease. Very rarely, a boy is born with a mutation that renders his […]Continue Reading ...
WEDNESDAY, April 17, 2019 — The death of brain cells may not be as sudden, or as irreversible, as previously believed. Four hours after a pig’s death, Yale scientists restored circulation and revived cellular activity within the dead animal’s brain. The cells of the brain remained viable six hours later, compared with other brains not […]Continue Reading ...
New North Carolina State University research shows that key proteins known for their ability to prevent viral infections by inducing cell death can also block certain bacterial infections without triggering the death of the host cells. Rather than killing host cells infected by Listeria in the gastrointestinal tract, the RIPK3 and MLKL proteins recognize the […]Continue Reading ...
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