Lingering inflammation in the colon is a known risk factor for colorectal cancer and now scientists report one way it resets the stage to enable this common and often deadly cancer. Inflammation is supposed to be a short-term response to an infection or other irritant in the body that is essential to eliminating it. But […]Continue Reading ...
WEDNESDAY, Oct. 31, 2018 — A healthy diet may lower your risk of death from colon cancer, even if you wait until after you’re diagnosed with the disease, new research suggests. The study included more than 2,800 colon cancer patients. Those whose eating habits before their cancer diagnosis most closely matched American Cancer Society dietary […]Continue Reading ...
Pre-operative treatment with a combination of the immune checkpoint inhibitors nivolumab and ipilimumab achieves major pathological responses in 100% of early-stage colon cancers with mismatch repair deficiencies, according to results reported at ESMO 2018 from the first exploratory phase II trial to investigate this approach. Restoring patients’ immune response against cancer cells with checkpoint inhibitors […]Continue Reading ...
“With our study we originally wanted to study the role of bacteria in the intestines in the development of intestinal inflammation,” explains Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Centre of the TUM. “However, the surprising result for us was the discovery that bacteria together with stress in […]Continue Reading ...
By Sally Robertson, BScAugust 15, 2018 Researchers from the Francis Crick Institute have revealed how vegetables such as broccoli, cabbage and kale help to maintain a healthy gut and protect against colon cancer. Image Credit: Chris Schiering / Francis Crick Institute The researchers showed that a diet rich in a chemical called indole-3-carbinol, which is […]Continue Reading ...
July 24, 2018 Patients with colorectal cancer tumors on the right side may have poorer five-year survival rates than those whose tumors are located on the left side. However, a new large-scale retrospective study is the first to demonstrate a potential improvement of these outcomes. Study results show that nearly doubling the benchmark number of […]Continue Reading ...
July 12, 2018 Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine. More than a million people […]Continue Reading ...
May 17, 2018 Researchers from Case Western Reserve University School of Medicine have discovered how unusually long strands of RNA help colon cancer cells avoid death, allowing unregulated growth. Unlike other RNAs, the intriguing strands do not appear to encode proteins and are termed “long non-coding RNAs” or “lincRNAs.”A new study showed some lincRNAs could […]Continue Reading ...
Scientists at the School of Medicine will launch a center to map the mosaic of cells that comprise the human colon. Michael Snyder, PhD, professor and chair of genetics, and Garry Nolan, PhD, professor of microbiology and immunology, will lead the Stanford Tissue Mapping Center, which is being funded by $4.9 million from the National […]Continue Reading ...
THURSDAY, Oct. 11, 2018 — While rates of colon cancer have declined among people 50 and older, they’re on the rise for younger Americans. Now, new research suggests widening waistlines may be one reason why. In the study, women aged 20 to 49 who were overweight or obese had up to twice the risk for […]Continue Reading ...
The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation. A new study carried out by a team led by Professor Heiko […]Continue Reading ...
FRIDAY, July 20, 2018 — A new study suggests that colon cancer patients who regularly drink diet sodas have a much lower risk of their tumor coming back, or of dying from the cancer. In a study funded by the U.S. National Cancer Institute, researchers tracked outcomes for more than 1,000 colon cancer patients. The […]Continue Reading ...
July 18, 2018 Researchers at Boston University School of Medicine (BUSM) have identified a new potential target protein (c-Cbl) they believe can help further the understanding of colon cancer and ultimately survival of patients with the disease. They found colon cancer patients with high levels of c-Cbl lived longer than those with low c-Cbl. Even […]Continue Reading ...
July 11, 2018 Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine. More than a million people […]Continue Reading ...
May 16, 2018 Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed. The study, which will be published May 16 in the Journal of Experimental Medicine, suggests that combination […]Continue Reading ...
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