Researchers report the identification of a novel transcription factor that helps regulate the differentiation of mesenchymal stem cells (MSCs) into bone in mice. Bone cell differentiation is still poorly understood, and MSCs offer a promising source of stem cells for regenerative medicine applications. The new transcription factor, called Osteoblast Inducer (ObI)-1, is described in an […]Continue Reading ...
Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die–a process known as apoptosis. When growth factor levels are too high or too low, or when […]Continue Reading ...
A group of researchers affiliated to the University of São Paulo (USP) – campus Ribeirão Preto, Brazil, used big data tools such as data mining and network analysis to develop a method to help scientists and companies identify technological routes, trends and partnerships in any knowledge area. For this purpose, it collected information from patent […]Continue Reading ...
What are Coagulation Factor Tests? Coagulation factors are proteins in the blood that help control bleeding. You have several different coagulation factors in your blood. When you get a cut or other injury that causes bleeding, your coagulation factors work together to form a blood clot. The clot stops you from losing too much blood. […]Continue Reading ...
Cambridge, Ma. – April 17, 2018 – Shire plc (LSE: SHP, NASDAQ: SHPG), the global biotechnology leader in rare disease, today announced the U.S. Food and Drug Administration (FDA) has approved Vonvendi [von Willebrand factor (recombinant)], a recombinant von Willebrand factor (rVWF) treatment for perioperative management of bleeding in adults (age 18 and older) with […]Continue Reading ...
New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women. The genetic factor, located on chromosome 6, increases the risk of developing spontaneous coronary artery dissection (SCAD). […]Continue Reading ...
June 30, 2018 A research team found a novel function of fibroblast growth factor 2 (FGF2), a self-renewal factor for spermatogonial stem cell (SSC) which is the origin of the sperm production. Although it has demonstrated that both FGF2 and glial cell line-derived neurotrophic factor (GDNF) is indispensable for SSC self-renewal and survival in vitro, […]Continue Reading ...
FDA Approves Portola Pharmaceuticals’ Andexxa, First and Only Antidote for the Reversal of Factor Xa Inhibitors SOUTH SAN FRANCISCO, Calif., May 03, 2018 (GLOBE NEWSWIRE) — Portola Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved Andexxa [coagulation factor Xa (recombinant), inactivated-zhzo], the first and only antidote indicated for patients […]Continue Reading ...
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