Genetics determines some proteins in HDL, but others are picked up by chance Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over […]Continue Reading ...
Feb 12 2019 Using puzzle pieces from four different DNA analyses, researchers at Karolinska Institutet in Sweden have been able to map three extremely complex chromosome aberrations. This has given families answers about the cause of their children’s serious symptoms. The study was published in the scientific journal PLOS Genetics and the goal is to […]Continue Reading ...
A team of Vanderbilt University Medical Center researchers, working with the U.S. Department of Veteran’s Affairs (VA), has discovered genetic associations with blood pressure that could guide future treatments for patients with hypertension. The study, an international effort using data from sources including the VA Million Veteran Program (MVP) and United Kingdom (UK) Biobank, is […]Continue Reading ...
Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team led by Adrian […]Continue Reading ...
A recent study from Uppsala University has found that whether you store your fat around the trunk or in other parts of your body is highly influenced by genetic factors and that this effect is present predominantly in women and to a much lower extent in men. In the study, which is published in Nature […]Continue Reading ...
It’s no surprise to scientists that variety is the very essence of biology, not just the seasoning, but most previous studies of key brain cells have found little variability in a common cell process that involves how genetic information is read and acted on. The process, called epigenetics, involves chemical or structural “tweaks” to gene […]Continue Reading ...
A growing number of genomic studies have generated important discoveries regarding human health and behavior, but new research from the University of Oxford suggests that scientific advancement is limited by a lack of diversity. They show that the people studied in genetic discovery research continue to be overwhelmingly of European descent, but also for the […]Continue Reading ...
New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women. The genetic factor, located on chromosome 6, increases the risk of developing spontaneous coronary artery dissection (SCAD). […]Continue Reading ...
Credit: CC0 Public Domain Genetic testing improves the diagnoses of abnormalities in developing babies that are picked up during ultrasound scans, scientists report today (31 January) in The Lancet. Scientists from the Wellcome Sanger Institute, University of Cambridge, University of Birmingham, Great Ormond Street Hospital (GOSH) and their collaborators used genome sequencing to improve the […]Continue Reading ...
There is only scant scientific evidence available on whether the genetic risk for developing specific psychiatric disorders or cognitive traits is manifest in brain structure from childhood and, to date, studies have focused primarily on adult populations. The question remains unanswered. New evidence has now been provided by a study led by a researcher from […]Continue Reading ...
Credit: CC0 Public Domain In the largest genetic study of osteoarthritis to date, scientists have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the disabling condition. Scientists at the Wellcome Sanger Institute, GSK and their collaborators analysed the genomes of over 77,000 people with osteoarthritis. […]Continue Reading ...
Jan 14 2019 As part of an international research project, a group of scientists from the University of Zurich found genetic variants associated with risk tolerance and risky behaviors. It is one of the first studies to link genetic variants with behavioral outcomes, which are relevant to social science research. If we compare two people’s […]Continue Reading ...
Credit: CC0 Public Domain Disorders of the autistic spectrum have been associated with hundreds of genetic variations, which have helped in identifying disturbed intracellular signalling pathways and molecular mechanisms typical to autism. Many gene mutations related to the autism spectrum disorders reside in a gene that produces a protein relevant to synapses, or is important […]Continue Reading ...
Almost half of all Americans take a vitamin supplement, and yet many large-scale, placebo-controlled clinical trials of various supplements have found little or no benefit. A new study led by investigators from Brigham and Women’s Hospital suggests an intriguing reason for this: genetic variation may be influencing these effects, increasing risk in some individuals while […]Continue Reading ...
Newer genetic tests introduce more ambiguity, but a new study finds patients are not overreacting to uncertain results As genetic testing for breast cancer has become more complex, evaluating a panel of multiple genes, it introduces more uncertainty about the results. But a new study finds that newer, more extensive tests are not causing patients […]Continue Reading ...
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