Dec 12 2018 The European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group and Protagen AG today announced a collaboration to utilize Protagen’s Cancer Immunotherapy Array to identify autoantibody biomarkers that investigate the immunological profile and immuno-competence of long-term Glioblastoma survivors. Glioblastoma is the most common glial brain tumor with an annual […]Continue Reading ...
Glioblastoma, a deadly brain cancer that has grabbed headlines for claiming the lives of Sens. Edward Kennedy and John McCain, could be “tricked” into sparing more of its victims. A team of University of Arizona researchers who looked for genetic differences between glioblastoma cells from long- and short-term survivors discovered that those who survived longer […]Continue Reading ...
Today, Penn Medicine is announcing the newest Translational Center of Excellence (TCE) in the Abramson Cancer Center, focused on Glioblastoma Multiforme, the most common and lethal form of brain cancer. The team will investigate new immune therapies for glioblastoma and, in particular, design and test new CAR T cell therapies. This involves engineering patients’ T […]Continue Reading ...
Researchers at The University of Texas Medical Branch at Galveston have successfully harnessed a Zika virus vaccine under development to target and kill the brain cancer known as glioblastoma. The findings are currently available in MBio. The Zika virus can cause microcephaly, a condition where the fetal brain doesn’t fully develop when a pregnant woman […]Continue Reading ...
Scientists with the Virginia Tech Carilion Research Institute say a gene involved in the body’s circadian rhythms is a potential target for therapies to help patients with a deadly form of brain cancer known as glioblastoma. This discovery, to be published in the journal Scientific Reports on Tuesday, Sept. 11, points to a subtype of […]Continue Reading ...
The death today of Sen. John McCain (R-Ariz.) sheds a new light on glioblastoma, a form of brain cancer that the American Brain Tumor Association estimated would be diagnosed in nearly 13,000 people this year. “Glioblastoma makes up about 60 percent of what we call primary brain tumors, tumors that start within the brain,” said […]Continue Reading ...
August 2, 2018 A new study by KAIST researchers identified where the mutation causing glioblastoma starts. According to the study, neural stem cells away from the tumor mass are the cells of origin that contain mutation drivers for glioblastoma, one of the most aggressive brain tumor. This breakthrough research, reported in Nature on August 1, […]Continue Reading ...
Electron microscopic image of a single human lymphocyte. Credit: Dr. Triche National Cancer Institute A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy. Paradoxically, the sending cells in this signaling are glioblastoma cells that are undergoing programmed cell death, or apoptosis, […]Continue Reading ...
Glioblastoma is a serious and incurable brain cancer. Patients receiving this diagnosis typically have 11-20 months to live. One of the main difficulties in treating this cancer is that its cells quickly build up a resistance to chemotherapy. In the upcoming issue of Nucleic Acids Research, Professor Rotem Karni and his team at Hebrew University’s […]Continue Reading ...
A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in […]Continue Reading ...
Rush University Medical Center is part of a new clinical trial testing whether an experimental vaccine can help patients’ immune systems stop the spread of glioblastoma — an aggressive form of brain cancer with very few current treatment options. Led by neuro-oncologist Clement Pillainayagam, MD, the phase II clinical trial is testing an investigational vaccine […]Continue Reading ...
An aggressive brain tumor (glioblastoma), illustrated based on magnetic resonance data. Credit: Karl-Heinz Nenning Glioblastoma is a highly aggressive brain cancer that predominantly affects people in their 50s, 60s and 70s. Even under the best available care, half of the patients die within one year after diagnosis, and very few live on for more than […]Continue Reading ...
August 13, 2018 Glioblastoma brain tumors can have an unusual effect on the body’s immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body’s defenses. Where the T-cells go has been unclear, even as immunotherapies are increasingly employed to stimulate the body’s natural ability to fight invasive […]Continue Reading ...
June 30, 2018 The California Institute for Regenerative Medicine (CIRM) board has awarded City of Hope $3.7 million to develop a phase 1 clinical trial for glioblastoma patients that will genetically engineer their stem cells to better tolerate chemotherapy’s side effects, allowing them to receive higher doses of the therapy. Grant funds will be used […]Continue Reading ...
June 22, 2018 A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy. Paradoxically, the sending cells in this signaling are glioblastoma cells that are undergoing programed cell death, or apoptosis, according to research by a team at institutes in the United […]Continue Reading ...
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