The elderly suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long known that a weakened immune system is to blame but the exact mechanisms behind this lagging immunity have remained largely unknown. Now research led by investigators at Harvard Medical School suggests that weakened metabolism of […]Continue Reading ...
The Allen Institute today announced the launch of the Allen Institute for Immunology, a new division of the Institute that is dedicated to studying the human immune system. Seeded by a generous commitment of $125 million by Allen Institute founder, the late Paul G. Allen, the new Institute will work to understand the dynamic balancing […]Continue Reading ...
The Allen Institute today announced the launch of the Allen Institute for Immunology, a new division of the Institute that is dedicated to studying the human immune system. The new Institute will work directly with the University of Colorado Anschutz Medical Campus and other leading research organizations to understand the dynamic balancing act of the […]Continue Reading ...
Researchers at the Norwegian University of Science and Technology (NTNU) have made an important new discovery about how the immune system handles infection. Rost9 | Shutterstock The finding could improve understanding of a range of diseases and lead to the development of more effective treatment approaches. Professor Egil Lien (NTNU Centre of Molecular Inflammation Research) […]Continue Reading ...
For the first time, researchers have identified that an immune cell subset called gamma delta T cells that may be causing and/or perpetuating the systemic inflammation found in normal aging in the general geriatric population and in HIV-infected people who are responding well to drugs (anti-retrovirals). Even with effective viral control, HIV-infected individuals are at […]Continue Reading ...
A team from the Research Institute of the McGill University Health Centre (RI-MUHC) led by Dr. Donald Vinh, the RI’s so-called “Dr. House” because of his research into rare diseases, has discovered a new human disease and the gene responsible for it, paving the way for the proper diagnosis of patients globally and the development […]Continue Reading ...
With a new crew arriving at the International Space Station, astronauts will be relieved to know that they won’t have to worry about a major aspect of their immune system being compromised. While researchers know a lot about astronauts’ skeletal and muscular health during spaceflight and when they return to Earth, much less is known […]Continue Reading ...
Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis (MS), shows that they might have a significant role in the […]Continue Reading ...
A team of researchers at the Australian National University have made an important discovery that could help save patients with bacterial infections, particularly those suffering from food poisoning. Australian University | Shutterstock One of the most common causes of food poisoning is a bacterium called Bacillus cereus, which secretes the toxins that cause vomiting and […]Continue Reading ...
Lack of Foxp1 leads to inflammation of the large intestine (colitis). (Left) In healthy conditions, iTreg cells (blue) with sufficient Foxp1 keep a check over other immune cells (T-cells, orange, green and purple) in the large intestine. (Right) If Foxp1 is absent, iTreg cells are dramatically reduced and therefore can’t control the activity of other […]Continue Reading ...
A new study by investigators from Brigham and Women’s Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 (hTIM-3). Understanding the atomic structure of hTIM-3 provides new insights for targeting this protein for numerous cancer and autoimmune therapeutics currently under clinical development. […]Continue Reading ...
Microglia. Credit: nei.nih.gov Using an animal model of chronic stress, researchers at The Ohio State University have shown that the immune cells of the brain, called microglia, hold unique signatures of chronic stress that leave the animal more sensitive to future stressful experiences, evident by increased anxiety and immune responses. Eliminating microglia so that these […]Continue Reading ...
Credit: CC0 Public Domain New research reveals how a single protein interferes with the immune system when exposed to the bacterium that causes Legionnaires’ disease, findings that could have broad implications for development of medicines to fight disease and infection. “Our immune system protects us from deadly infections, but successful pathogens have evolved many effective […]Continue Reading ...
Together with colleagues from Sweden and Luxembourg, scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have observed that, during a natural vaginal birth, specific bacteria from the mother’s gut are passed on to the baby and stimulate the baby’s immune responses. This transmission is impacted in children born by […]Continue Reading ...
Researchers at the Mainz University Medical Center discovered a new signal pathway employed by skin cancer cells to avoid attack by the immune system. In an animal model and through analysis of human tissue samples, Dr. Toszka Bohn, Dr. Steffen Rapp and Professor Tobias Bopp were able to demonstrate the significant role played by a […]Continue Reading ...
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