Melanoma patients with a history of smoking cigarettes are 40 per cent less likely to survive their skin cancer than people who have never smoked, according to a new report funded by Cancer Research UK. The study of more than 700 melanoma patients mainly from the north of England – and published today in Cancer […]Continue Reading ...
A research team at the University of Louisville has discovered that an immune checkpoint molecule they developed for cancer immunotherapy, also protects against future development of multiple types of cancer when administered by itself. The recombinant protein molecule SA-4-1BBL has been used to enhance the therapeutic efficacy of cancer vaccines with success in pre-clinical animal […]Continue Reading ...
Researchers Professor Graham Lord, from The University of Manchester and colleagues have found that a specific part of the immune system could have the tools that may help in the therapy of some major diseases such as diabetes, cancer, multiple sclerosis, Crohn’s disease and other autoimmune diseases. The results of their findings were published in […]Continue Reading ...
Researchers Subhash Tripathi, Ankitha Shetty and Tommi Välikangas from Turku Centre for Biotechnology celebrate the new publication. The study is part of the dissertation research of Ankitha Shetty and Tommi Välikangas. The research groups of Academy Professor Riitta Lahesmaa and Research Director Laura Elo from Turku Centre for Biotechnology have discovered new proteins that regulate […]Continue Reading ...
Inflammation is the response of our immune system to infection and harmful environmental effects. On one hand, it is beneficial as it defends our body against microbes. On the other hand, excessive inflammation leads to serious diseases. A recent research published in Nature Communications reveals details on inflammation initiation through engagement of protein called NLRP3. […]Continue Reading ...
La Jolla Institute for Immunology (LJI) has been awarded a $22 million contract renewal over seven years from the National Institutes of Health (NIH) to host and expand the Immune Epitope Database (IEDB). The database is the world’s most comprehensive collection of scientific data on how the immune system responds to a wide range of […]Continue Reading ...
If this triggers an excessive reaction of the immune system, the body’s own tissue can be attacked and damaged. The overreaction eventually leads to a life-threatening collapse of the body’s defenses. In Germany alone, more people die of sepsis than of AIDS, colon cancer and breast cancer combined. Researchers around the world are on the […]Continue Reading ...
For the first time ever, researchers are comprehensively sequencing the human immune system, which is billions of times larger than the human genome. In a new study published in Nature from the Human Vaccines Project, scientists have sequenced a key part of this vast and mysterious system — the genes encoding the circulating B cell […]Continue Reading ...
A research team from Tübingen and Göttingen has described in the renowned journal Cell Reports a new mechanism how the Ebola virus escapes the immune system. The virus causes infected cells to release decoys that inactivate neutralizing antibodies and prevent immune cells from releasing important messenger molecules. These findings could lead to the development of […]Continue Reading ...
Researchers at the University of Jena in Germany have discovered how Aspergillus fumigatus suppresses immune defences to enable the infection to become fatal. Shutterstock | woflness72 The fungus produces a potent mycotoxin that inhibits a messenger molecule responsible for recruiting immune cells that gather to fight off the invader. Aspergillus fumigatus occurs virtually everywhere, as […]Continue Reading ...
Research team from the University of Jena (Germany) clarifies the mechanism of gliotoxin, a mycotoxin from the fungus Aspergillus fumigatus. The researchers present their findings in the current issue of the specialist journal Cell Chemical Biology. It is everywhere – and it is extremely dangerous for people with a weakened immune system. The fungus Aspergillus […]Continue Reading ...
Researchers at The University of Texas MD Anderson Cancer Center have discovered an immune regulator that appears to dictate glioblastoma (GBM) progression by shutting down immune surveillance, indicating a potential new area of therapeutic investigation. Findings from the preclinical study led by Shulin Li, Ph.D., professor of Pediatrics, and Amy Heimberger, M.D., professor of Neurosurgery, […]Continue Reading ...
Having ancestors who were frequently exposed to stressors can improve one’s own immune response to stressors, according to Penn State researchers. The results suggest that family history should be considered to predict or understand the health implications of stress. “Prolonged stress typically suppresses immune function within an individual,” said Tracy Langkilde, professor and head of […]Continue Reading ...
CAMBRIDGE, Mass., Jan. 23, 2019—Vedanta Biosciences, a clinical-stage company developing a new category of therapies for immune-mediated diseases based on rationally-defined consortia of human microbiome-derived bacteria, today announced a publication in Nature that revealed a newly discovered mechanism underlying antitumor immunity that involves human microbiota-driven induction of interferon-gamma-producing (IFNy+) CD8+ T cell accumulation in the […]Continue Reading ...
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