Nov 16 2018 Their ambitious attempt to improve the diagnosis of malaria in developing countries, has clinched them the runner-up spot in the international James Dyson Award 2018 Over 212 million cases of malaria are reported annually, with the majority of incidences occuring in Sub-Saharan Africa. However, a lack of medical resources means blood sample […]Continue Reading ...
It is already known that dogs with their sharp noses can sniff out a host of human diseases including cancers. A new study has now shown that dogs could possibly detect and diagnose a person suffering from malaria. Clues from this technology is now helping scientists to develop an accurate diagnostic technology that can detect […]Continue Reading ...
A breakthrough in monkey malaria research by University of Otago scientists encouraged the Bill & Melinda Gates Foundation to fund a special meeting in Dunedin recently. A rare form of monkey malaria has been recently implicated in a spate of malaria cases in Malaysia. Professor Bruce Russell from the Department of Microbiology and Immunology at […]Continue Reading ...
Scientists from Massachusetts Institute of Technology (MIT), Singapore-MIT Alliance for Research and Technology (SMART) and Nanyang Technological University, Singapore (NTU Singapore) have discovered a potential treatment that could be effective against severe malaria and even drug-resistant malaria. The joint research team discovered a new molecular pathway (a new series of interactions among molecules in a […]Continue Reading ...
The team from Imperial College London were able to crash caged populations of the malaria vector mosquito Anopheles gambiae in only 7-11 generations. This is the first time experiments have been able to completely block the reproductive capacity of a complex organism in the laboratory using a designer molecular approach. The technique, called gene drive, […]Continue Reading ...
After decades a new drug against malaria has been developed and first clinical trials of this new investigational drug is soon to begin. Enrolment for the same has already started. This study is to be sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health (NIH). It is […]Continue Reading ...
A new mathematical model for malaria shows how competition between parasite strains within a human host reduces the odds of drug resistance developing in a high-transmission setting. But if a drug-resistant strain does become established, that same competition drives the spread of resistance faster, under strong selection from antimalarial drug use. “It’s basically a numbers […]Continue Reading ...
A woman in Cambodia being tested for malaria. Photo: USAID/Richard Nyberg. CC BY-NC 2.0 The first-line treatment for malaria in no longer effective in Cambodia, and a new report from researchers at Columbia University Vagelos College of Physicians and Surgeons has identified the likely culprit—a mutated gene in the malaria parasite. Why the study is […]Continue Reading ...
Scientists investigating how the human immune system defends against malaria have uncovered a rare phenomenon: antibodies working together to bind to a vulnerable spot on the parasite. The new research, published recently in Science Advances, shows that antibodies working together can result in a protein on the parasite’s cell surface locking it into a spiral […]Continue Reading ...
For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans. This unique approach — in which immunized humans transfer anti-malarial proteins to mosquitoes when bitten — is called a transmission-blocking vaccine (TBV). A few malarial TBVs have shown promise but they have not been widely tested due […]Continue Reading ...
Malaria parasites have evolved to be most infectious at the time of day when mosquitoes feed, to maximize the chance of being spread, research shows. The finding explains why people with the disease experience regular bouts of fever. These occur as the parasites that cause malaria replicate in the bloodstream of infected people or animals, […]Continue Reading ...
FRIDAY, Sept. 21, 2018 — Malaria is transmitted by mosquitoes carrying malaria parasites, but scientists report they have discovered compounds that might keep mosquitoes from spreading the sometimes deadly disease. “Current anti-malarial drugs can cure a person of the disease, but that person is still infectious to mosquitoes, and can therefore still cause someone else […]Continue Reading ...
A new study published in the Lancet journal EClinicalMedicine suggests that more mosquito nets are likely needed between mass campaigns to keep malaria cases in check. Writing in an accompanying commentary, Johns Hopkins Center for Communication Programs’ Hannah Koenker, PhD, says the paper shows that the loss of treated bed nets between mass campaigns may […]Continue Reading ...
There are more clinical phenotypes of severe malaria than those defined by the World Health Organization (WHO), according to a study led by ISGlobal, an institution supported by “la Caixa” Foundation. The results indicate that heart failure can be a pathogenic mechanism of disease, which has implications in the clinical management of these patients. Despite […]Continue Reading ...
Credit: CC0 Public Domain A new type of bed net could prevent millions of cases of malaria, according to new research published in The Lancet today. The two-year clinical trial in Burkina Faso, West Africa involving 2,000 children showed that the number of cases of clinical malaria was reduced by 12 per cent with the […]Continue Reading ...
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