Mar 22 2019 In an article published today in Lancet Planetary Health, a team from the Ifakara Health Institute (IHI) and Liverpool School of Tropical Medicine (LSTM), provides evidence that even window screens with no insecticide suppressed mosquito populations and dramatically reduced malaria prevalence in the Tanzanian city of Dar es Salaam. The study team […]Continue Reading ...
New research suggests an earlier emergence of malaria in Africa. Credit: Institut Pasteur Malaria claims hundreds of thousands of lives each year—mainly children, and especially in Africa. It is one of the leading causes of death by an infectious agent, the Plasmodium falciparum parasite. In research on malaria, the genetic mutation that causes sickle cell […]Continue Reading ...
This photomicrograph of a blood smear contains a macro- and microgametocyte of the Plasmodium falciparum parasite. Credit: Wikipedia. Mosquitoes that landed on surfaces coated with the anti-malarial compound atovaquone were completely blocked from developing Plasmodium falciparum (P. falciparum), the parasite that causes malaria, according to new research led by Harvard T.H. Chan School of Public […]Continue Reading ...
The anopheline mosquitoes that carry malaria were present 100 million years ago, new research shows, potentially shedding fresh light on the history of a disease that continues to kill more than 400,000 people annually. “Mosquitoes could have been vectoring malaria at that time, but it’s still an open question,” said the study’s corresponding author, George […]Continue Reading ...
Early research on a new approach to protecting against malaria is offering promising, potentially long-lasting results against the persistent parasite that sickens hundreds of millions people each year. The approach uses a cytomegalovirus-based platform that’s already being used in vaccines being developed to battle HIV and tuberculosis. This new vaccine reduced the malaria-causing parasite’s release […]Continue Reading ...
Vivax malaria is a serious illness with high fever that, if untreated, can keep people bed-ridden for weeks or even months. But even after successful treatment, it’s tricky: although the current, commonly-used drugs successfully treat the blood stage of vivax malaria, they are unable to prevent malaria parasites from invading the liver (liver stage) and […]Continue Reading ...
A team at LSTM with their collaborators in Malawi and Denmark have provided, for the first time, evidence which links the ability of red blood cells infected with the malaria parasite to bind to the cells lining the blood vessels of the brain, with the clinical syndrome cerebral malaria. Cerebral malaria is a life-threatening complication […]Continue Reading ...
A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite’s metabolic function leading to parasite death. Despite concerted efforts for malaria elimination, this deadly disease remains a major health threat to the developing world. The causative agent […]Continue Reading ...
For decades, one of the strongest weapons against malaria has been a one-two punch: low-tech mosquito bed nets to physically block biting, treated with deadly insecticides to kill the mosquitoes. With widespread use of this combination, malaria deaths have dropped significantly — though nearly 445,000 people died from the disease in 2016 alone. But now […]Continue Reading ...
“Spit here, please.” Will this become the instruction we receive upon entering clinics, schools, apothecaries and ports of entry throughout the globe? One of the main factors enabling the continued transmission of malaria are individuals who are free from symptoms but carry the malaria parasite in their blood. However, the parasite numbers in the blood […]Continue Reading ...
Scientists at the Institute of Genome Sciences (IGS) at the University of Maryland School of Medicine (UMSOM) have developed a novel way with genome sequences to study and better understand transmission, treat and ultimately eradicate Plasmodium vivax, the most widespread form of malaria. P. vivax is a single-celled transmitted by mosquitoes. It is the most […]Continue Reading ...
After major global successes in the battle against malaria, the positive trend stalled around 2015 – apart from in Zanzibar in East Africa, where only a fraction of the disease remains. In a new study published in BMC Medicine, researchers at Karolinska Institutet in Sweden explain why this was and show that new strategies are […]Continue Reading ...
A type of mosquito that transmits malaria has been detected in Ethiopia for the first time, and the discovery has implications for putting more people at risk for malaria in new regions, according to a study led by a Baylor University researcher. The mosquito, Anopheles stephensi, normally is found in the Middle East, Indian Subcontinent […]Continue Reading ...
ERADA Technology Alliance Ltd (ERADA), pioneers of innovative, rapid diagnostic solutions for early detection of infectious diseases, have announced the imminent launch of a world first diagnostic saliva test for malaria. The saliva-based diagnostic tool, to be marketed by ERADA as a Saliva-based Malaria Asymptomatic and Asexual Rapid Test (SMAART) for subclinical infection, is set […]Continue Reading ...
Electron microscope images of malaria parasite (blue; courtesy Dr Eric Hanssen) and a chemical structure of artemisinin (stick structure) which explodes inside the parasites. Credit: University of Melbourne Scientists have found a way to boost the efficacy of the world’s most powerful antimalarial drug with the help of chemotherapy medicines, according to new research published […]Continue Reading ...
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